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Protein-protein interaction (PPI) extraction from published scientific literature provides additional support for precision medicine efforts. Meanwhile, knowledge bases (KBs) contain huge amounts of structured information of protein…
Medical image interpretation using deep learning has shown promise but often requires extensive expert-annotated datasets. To reduce this annotation burden, we develop an Image-Graph Contrastive Learning framework that pairs chest X-rays…
Graphs are a powerful tool for representing and analyzing unstructured, non-Euclidean data ubiquitous in the healthcare domain. Two prominent examples are molecule property prediction and brain connectome analysis. Importantly, recent works…
Recent work on predicting patient outcomes in the Intensive Care Unit (ICU) has focused heavily on the physiological time series data, largely ignoring sparse data such as diagnoses and medications. When they are included, they are usually…
Existing research usually utilizes side information such as social network or item attributes to improve the performance of collaborative filtering-based recommender systems. In this paper, the knowledge graph with user perception is used…
Knowledge based dialogue systems have attracted increasing research interest in diverse applications. However, for disease diagnosis, the widely used knowledge graph is hard to represent the symptom-symptom relations and symptom-disease…
Clinical evidence encompasses the associations and impacts between patients, interventions (such as drugs or physiotherapy), problems, and outcomes. The goal of recommending clinical evidence is to provide medical practitioners with…
Here we present a holistic approach for data exploration on dense knowledge graphs as a novel approach with a proof-of-concept in biomedical research. Knowledge graphs are increasingly becoming a vital factor in knowledge mining and…
Predicting molecule-protein interactions (MPIs) is a fundamental task in computational biology, with crucial applications in drug discovery and molecular function annotation. However, existing MPI models face two major challenges. First,…
Recent years have witnessed the fast development of large-scale pre-training frameworks that can extract multi-modal representations in a unified form and achieve promising performances when transferred to downstream tasks. Nevertheless,…
In recent years, knowledge graphs have been integrated into recommender systems as item-side auxiliary information, enhancing recommendation accuracy. However, constructing and integrating structural user-side knowledge remains a…
Imaging-derived phenotypes (IDPs) summarize multi-organ physiology but provide only static snapshots of diseases that evolve over time. In contrast, longitudinal electronic health records encode disease trajectories through temporal…
Generative paradigm, especially powered by Large Language Models (LLMs), has emerged as a new solution to the next point-of-interest (POI) recommendation. Pioneering studies usually adopt a two-stage pipeline, starting with a tokenizer…
In the era of increasingly complex AI models for time series forecasting, progress is often measured by marginal improvements on benchmark leaderboards. However, this approach suffers from a fundamental flaw: standard evaluation metrics…
In this work, we propose a novel goal-oriented dialog task, automatic symptom detection. We build a system that can interact with patients through dialog to detect and collect clinical symptoms automatically, which can save a doctor's time…
Medical text learning has recently emerged as a promising area to improve healthcare due to the wide adoption of electronic health record (EHR) systems. The complexity of the medical text such as diverse length, mixed text types, and full…
Addressing the challenges related to data sparsity, cold-start problems, and diversity in recommendation systems is both crucial and demanding. Many current solutions leverage knowledge graphs to tackle these issues by combining both…
Protein-protein interaction (PPI) extraction from published scientific literature provides additional support for precision medicine efforts. However, many of the current PPI extraction methods need extensive feature engineering and cannot…
While pioneering deep learning methods have made great strides in analyzing electronic health record (EHR) data, they often struggle to fully capture the semantics of diverse medical codes from limited data. The integration of external…
The use of narratives as a means of fusing information from knowledge graphs (KGs) into a coherent line of argumentation has been the subject of recent investigation. Narratives are especially useful in event-centric knowledge graphs in…