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The last decade has seen significant advances in computer-aided diagnostics for cytological screening, mainly through the improvement and integration of scanning techniques such as whole slide imaging (WSI) and the combination with deep…

Signal Processing · Electrical Eng. & Systems 2026-01-23 Philip Groult , Julia D. Sistermanns , Ellen Emken , Oliver Hayden , Wolfgang Utschick

Despite remarkable efforts been made, the classification of gigapixels whole-slide image (WSI) is severely restrained from either the constrained computing resources for the whole slides, or limited utilizing of the knowledge from different…

Computer Vision and Pattern Recognition · Computer Science 2022-07-13 Ming Feng , Kele Xu , Nanhui Wu , Weiquan Huang , Yan Bai , Changjian Wang , Huaimin Wang

Hallucination remains a key obstacle to the reliable deployment of large language models (LLMs) in real-world question answering tasks. A widely adopted strategy to detect hallucination, known as self-assessment, relies on the model's own…

Artificial Intelligence · Computer Science 2025-06-04 Jinyuan Luo , Zhen Fang , Yixuan Li , Seongheon Park , Ling Chen

Diffusion models are prone to generating structural hallucinations - samples that match the statistical properties of the training data yet defy underlying structural rules, resulting in anomalies like hands with more than five fingers.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Bartlomiej Sobieski , Matthew Tivnan , Dawid Płudowski , Michał Jan Włodarczyk , Pengfei Jin , Przemyslaw Biecek , Quanzheng Li

Whole slide imaging (WSI) has moved digital pathology closer to diagnostic practice in recent years. Due to the inherent tissue topography variability, accurate autofocusing remains a critical challenge for WSI and automated microscopy…

Weakly supervised whole slide image classification is a key task in computational pathology, which involves predicting a slide-level label from a set of image patches constituting the slide. Constructing models to solve this task involves…

Accurate diagnosis of disease often depends on the exhaustive examination of Whole Slide Images (WSI) at microscopic resolution. Efficient handling of these data-intensive images requires lossy compression techniques. This paper…

In lossy image compression, models face the challenge of either hallucinating details or generating out-of-distribution samples due to the information bottleneck. This implies that at times, introducing hallucinations is necessary to…

Image and Video Processing · Electrical Eng. & Systems 2025-03-07 Till Aczel , Roger Wattenhofer

Despite significant progress in the quality of language generated from abstractive summarization models, these models still exhibit the tendency to hallucinate, i.e., output content not supported by the source document. A number of works…

Computation and Language · Computer Science 2022-11-01 Liam van der Poel , Ryan Cotterell , Clara Meister

Image captioning, which generates natural language descriptions of the visual information in an image, is a crucial task in vision-language research. Previous models have typically addressed this task by aligning the generative capabilities…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 Qian Cao , Xu Chen , Ruihua Song , Xiting Wang , Xinting Huang , Yuchen Ren

Visual hallucinations in Large Language Models (LLMs), where the model generates responses that are inconsistent with the visual input, pose a significant challenge to their reliability, particularly in contexts where precise and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Nokimul Hasan Arif , Shadman Rabby , Md Hefzul Hossain Papon , Sabbir Ahmed

Large language models (LLMs) are prone to hallucinations, i.e., statements unsupported by the input or training data, hindering reliable deployment. In parallel, numerous uncertainty estimation (UE) methods have been proposed to quantify…

Computation and Language · Computer Science 2026-05-27 Yedidia Agnimo , Anna Korba , Annabelle Blangero , Nicolas Chesneau , Karteek Alahari

Diagnostic, prognostic and therapeutic decision-making of cancer in pathology clinics can now be carried out based on analysis of multi-gigapixel tissue images, also known as whole-slide images (WSIs). Recently, deep convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-09-08 Quoc Dang Vu , Kashif Rajpoot , Shan E Ahmed Raza , Nasir Rajpoot

Hallucinations in large language models (LLMs) refer to the phenomenon of LLMs producing responses that are coherent yet factually inaccurate. This issue undermines the effectiveness of LLMs in practical applications, necessitating research…

Computation and Language · Computer Science 2024-06-11 Weihang Su , Changyue Wang , Qingyao Ai , Yiran HU , Zhijing Wu , Yujia Zhou , Yiqun Liu

Hallucination has been a major problem for large language models and remains a critical challenge when it comes to multimodality in which vision-language models (VLMs) have to deal with not just textual but also visual inputs. Despite rapid…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Zhecan Wang , Garrett Bingham , Adams Yu , Quoc Le , Thang Luong , Golnaz Ghiasi

Hallucination is often regarded as a major impediment for using large language models (LLMs), especially for knowledge-intensive tasks. Even when the training corpus consists solely of true statements, language models still generate…

Computation and Language · Computer Science 2024-07-12 Yuji Zhang , Sha Li , Jiateng Liu , Pengfei Yu , Yi R. Fung , Jing Li , Manling Li , Heng Ji

Large language models are increasingly being used in patient-facing medical question answering, where hallucinated outputs can vary widely in potential harm. However, existing hallucination standards and evaluation metrics focus primarily…

Computation and Language · Computer Science 2026-03-02 Savan Doshi

During the inversion of discrete linear systems noise in data can be amplified and result in meaningless solutions. To combat this effect, characteristics of solutions that are considered desirable are mathematically implemented during…

Numerical Analysis · Mathematics 2023-02-07 Michael J. Byrne , Rosemary A. Renaut

Neural sequence generation models are known to "hallucinate", by producing outputs that are unrelated to the source text. These hallucinations are potentially harmful, yet it remains unclear in what conditions they arise and how to mitigate…

Computation and Language · Computer Science 2023-02-28 Weijia Xu , Sweta Agrawal , Eleftheria Briakou , Marianna J. Martindale , Marine Carpuat

Joint analysis of multiple biomarker images and tissue morphology is important for disease diagnosis, treatment planning and drug development. It requires cross-staining comparison among Whole Slide Images (WSIs) of immuno-histochemical and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-05 Abubakr Shafique , Morteza Babaie , Mahjabin Sajadi , Adrian Batten , Soma Skdar , H. R. Tizhoosh