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Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…

Medical Physics · Physics 2022-03-14 Zongsheng Hu , Zhenyu Yang , Haozhao Zhang , Eugene Vaios , Kyle Lafata , Fang-Fang Yin , Chunhao Wang

Glioblastoma is one of the most aggressive and deadliest types of brain cancer, with low survival rates compared to other types of cancer. Analysis of Magnetic Resonance Imaging (MRI) scans is one of the most effective methods for the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Huafeng Liu , Benjamin Dowdell , Todd Engelder , Zarah Pulmano , Nicolas Osa , Arko Barman

Precise prognostic modeling of glioblastoma (GBM) under varying treatment interventions is essential for optimizing clinical outcomes. While generative AI has shown promise in simulating GBM evolution, existing methods typically treat…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Chenhui Wang , Boyun Zheng , Liuxin Bao , Zhihao Peng , Peter Y. M. Woo , Hongming Shan , Yixuan Yuan

Background: This research aims to improve glioblastoma survival prediction by integrating MR images, clinical and molecular-pathologic data in a transformer-based deep learning model, addressing data heterogeneity and performance…

Glioblastomas are the most common malignant brain tumors in adults. Approximately 200000 people die each year from Glioblastoma in the world. Glioblastoma patients have a median survival of 12 months with optimal therapy and about 4 months…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Vikram Goddla

In advancing discrete-based computational cancer models towards clinical applications, one faces the dilemma of how to deal with an ever growing amount of biomedical data that ought to be incorporated eventually in one form or another.…

Cell Behavior · Quantitative Biology 2008-06-26 Le Zhang , L. Leon Chen , Thomas S. Deisboeck

Glioblastoma Multiforme (GBM) is a malignant brain cancer forming around 48% of al brain and Central Nervous System (CNS) cancers. It is estimated that annually over 13,000 deaths occur in the US due to GBM, making it crucial to have early…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Sauman Das

GBM (Glioblastoma multiforme) is the most aggressive type of brain tumor in adults that has a short survival rate even after aggressive treatment with surgery and radiation therapy. The changes on magnetic resonance imaging (MRI) for…

Image and Video Processing · Electrical Eng. & Systems 2023-06-07 M. S. Sadique , W. Farzana , A. Temtam , E. Lappinen , A. Vossough , K. M. Iftekharuddin

This study deliberates on the application of advanced AI techniques for brain tumor classification through MRI, wherein the training includes the present best deep learning models to enhance diagnosis accuracy and the potential of usability…

Glioblastoma is one of the most aggressive and common brain tumors, with a median survival of 10-15 months. Predicting Overall Survival (OS) is critical for personalizing treatment strategies and aligning clinical decisions with patient…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Yin Lin , Riccardo Barbieri , Domenico Aquino , Giuseppe Lauria , Marina Grisoli , Elena De Momi , Alberto Redaelli , Simona Ferrante

Glioblastoma Multiforme is a very aggressive type of brain tumor. Due to spatial and temporal intra-tissue inhomogeneity, location and the extent of the cancer tissue, it is difficult to detect and dissect the tumor regions. In this paper,…

Image and Video Processing · Electrical Eng. & Systems 2021-01-27 Snehal Rajput , Rupal Agravat , Mohendra Roy , Mehul S Raval

We propose predictive models that estimate GBM patients' health status of one-year after treatments (Classification task), predict the long-term prognosis of GBM patients at an individual level (Survival task). We used total of 467 GBM…

Machine Learning · Computer Science 2021-09-10 Yeseul Kim , Kyung Hwan Kim , Junyoung Park , Hong In Yoon , Wonmo Sung

Glioblastoma Multiforme is a high grade, very aggressive, brain tumor, with patients having a poor prognosis. Lower grade gliomas are less aggressive, but they can evolve into higher grade tumors over time. Patient management and treatment…

Computer Vision and Pattern Recognition · Computer Science 2018-11-01 Sergio Pereira , Raphael Meier , Victor Alves , Mauricio Reyes , Carlos A. Silva

The paper demonstrates the use of the fully convolutional neural network for glioma segmentation on the BraTS 2019 dataset. Three-layers deep encoder-decoder architecture is used along with dense connection at encoder part to propagate the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-23 Rupal Agravat , Mehul S Raval

Glioblastoma Multiforme (GBM) is a highly aggressive brain tumour with limited therapeutic options and poor prognosis. This study presents a mathematical framework to investigate the efficacy of immunotherapy strategies based on cytotoxic…

Populations and Evolution · Quantitative Biology 2025-12-23 Francesca Ballatore , Lorenzo Scolaris , Chiara Giverso

Glioblastoma multiforme (GBM) is an aggressive form of human brain cancer that is under active study in the field of cancer biology. Its rapid progression and the relative time cost of obtaining molecular data make other readily-available…

Applications · Statistics 2019-11-14 Lorin Crawford , Anthea Monod , Andrew X. Chen , Sayan Mukherjee , Raúl Rabadán

Glioblastomas are the most aggressive type of glioma, having a 5-year survival rate of 6.9%. Treatment typically involves surgery, followed by radiotherapy and chemotherapy, and frequent magnetic resonance imaging (MRI) scans to monitor…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Ana Matoso , Catarina Passarinho , Marta P. Loureiro , José Maria Moreira , Patrícia Figueiredo , Rita G. Nunes

Accurate characterization of glioma is crucial for clinical decision making. A delineation of the tumor is also desirable in the initial decision stages but is a time-consuming task. Leveraging the latest GPU capabilities, we developed a…

Background: Gliomas are the most common brain tumors, which vary from low to high-grade. Despite the improvements in imaging techniques in the last decade, all parts of the tumor are not visible in these images, due to having a threshold of…

Other Quantitative Biology · Quantitative Biology 2023-09-06 Farshad Samadifam , Ehsan Ghafourian
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