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Glioblastoma is profoundly heterogeneous in microstructure and vasculature, which may lead to tumor regional diversity and distinct treatment response. Although successful in tumor sub-region segmentation and survival prediction, radiomics…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Yifan Li , Chao Li , Stephen Price , Carola-Bibiane Schönlieb , Xi Chen

Accurately predicting early recurrence in brain tumor patients following surgical resection remains a clinical challenge. This study proposes a multi-modal machine learning framework that integrates structural MRI features with clinical…

Machine Learning · Computer Science 2025-09-03 Cheng Cheng , Zeping Chen , Rui Xie , Peiyao Zheng , Xavier Wang

The RSNA-MICCAI brain tumor radiogenomic classification challenge aimed to predict MGMT biomarker status in glioblastoma through binary classification on Multi parameter mpMRI scans: T1w, T1wCE, T2w and FLAIR. The dataset is splitted into…

Image and Video Processing · Electrical Eng. & Systems 2024-01-19 Amr Mohamed , Mahmoud Rabea , Aya Sameh , Ehab Kamal

Glioma is the most common and aggressive brain tumor. Magnetic resonance imaging (MRI) plays a vital role to evaluate tumors for the arrangement of tumor surgery and the treatment of subsequent procedures. However, the manual segmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Wenbo Zhang , Guang Yang , He Huang , Weiji Yang , Xiaomei Xu , Yongkai Liu , Xiaobo Lai

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Machine Learning · Computer Science 2022-07-20 Can Cui , Han Liu , Quan Liu , Ruining Deng , Zuhayr Asad , Yaohong WangShilin Zhao , Haichun Yang , Bennett A. Landman , Yuankai Huo

Survival prediction models can potentially be used to guide treatment of glioblastoma patients. However, currently available MR imaging biomarkers holding prognostic information are often challenging to interpret, have difficulties…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sveinn Pálsson , Stefano Cerri , Hans Skovgaard Poulsen , Thomas Urup , Ian Law , Koen Van Leemput

We proposed a fully automatic workflow for glioblastoma (GBM) survival prediction using deep learning (DL) methods. 285 glioma (210 GBM, 75 low-grade glioma) patients were included. 163 of the GBM patients had overall survival (OS) data.…

Medical Physics · Physics 2021-07-07 Jie Fu , Kamal Singhrao , Xinran Zhong , Yu Gao , Sharon Qi , Yingli Yang , Dan Ruan , John H Lewis

Complete resection of malignant gliomas is hampered by the difficulty in distinguishing tumor cells at the infiltration zone. Fluorescence guidance with 5-ALA assists in reaching this goal. Using hyperspectral imaging, previous work…

Glioblastoma (GBM) is one of the most aggressive and lethal human cancers. Intra-tumoral genetic heterogeneity poses a significant challenge for treatment. Biopsy is invasive, which motivates the development of non-invasive, MRI-based…

Glioblastoma is a highly malignant brain tumor with a life expectancy of only 3 to 6 months without treatment. Detecting and predicting its survival and grade accurately are crucial. This study introduces a novel approach using transfer…

Melanoma, one of most dangerous types of skin cancer, re-sults in a very high mortality rate. Early detection and resection are two key points for a successful cure. Recent research has used artificial intelligence to classify melanoma and…

Computer Vision and Pattern Recognition · Computer Science 2020-08-31 Cong Tri Pham , Mai Chi Luong , Dung Van Hoang , Antoine Doucet

Accurate differentiation of pseudoprogression (PsP) from True Progression (TP) following radiotherapy (RT) in glioblastoma (GBM) patients is crucial for optimal treatment planning. However, this task remains challenging due to the…

Radiomic models have been shown to outperform clinical data for outcome prediction in glioblastoma (GBM). However, clinical implementation is limited by lack of parameters standardization. We aimed to compare nine machine learning…

Segmentation of brain tumor from magnetic resonance imaging (MRI) is a vital process to improve diagnosis, treatment planning and to study the difference between subjects with tumor and healthy subjects. In this paper, we exploit a…

Image and Video Processing · Electrical Eng. & Systems 2021-04-05 Mobarakol Islam , V Jeya Maria Jose , Hongliang Ren

Glioblastoma is a highly aggressive and lethal form of brain cancer. Magnetic resonance imaging (MRI) plays a significant role in the diagnosis, treatment planning, and follow-up of glioblastoma patients due to its non-invasive and…

Quantitative Methods · Quantitative Biology 2023-11-16 Ibrahim Ethem Hamamci

Inspired by the success of Convolutional Neural Networks (CNN), we develop a novel Computer Aided Detection (CADe) system using CNN for Glioblastoma Multiforme (GBM) detection and segmentation from multi channel MRI data. A two-stage…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 Subhasis Banerjee , Sushmita Mitra , Anmol Sharma , B. Uma Shankar

Glioma, the malignant brain tumor, requires immediate treatment to improve the survival of patients. Gliomas heterogeneous nature makes the segmentation difficult, especially for sub-regions like necrosis, enhancing tumor, non-enhancing…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Rupal Agravat , Mehul S Raval

Glioblastoma is a highly aggressive and malignant brain tumor type that requires early diagnosis and prompt intervention. Due to its heterogeneity in appearance, developing automated detection approaches is challenging. To address this…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Ziya Ata Yazıcı , İlkay Öksüz , Hazım Kemal Ekenel

Glioblastoma, a highly aggressive brain tumor, poses major challenges due to its poor prognosis and high morbidity rates. Partial differential equation-based models offer promising potential to enhance therapeutic outcomes by simulating…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Zeineb Haouari , Jonas Weidner , Yeray Martin-Ruisanchez , Ivan Ezhov , Aswathi Varma , Daniel Rueckert , Bjoern Menze , Benedikt Wiestler

Gliomas are brain tumor types that have a high mortality rate which means early and accurate diagnosis is important for therapeutic intervention for the tumors. To address this difficulty, the proposed research will develop a hybrid deep…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Pandiyaraju V , Sreya Mynampati , Abishek Karthik , Poovarasan L , D. Saraswathi