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Optimal designs are usually model-dependent and likely to be sub-optimal if the postulated model is not correctly specified. In practice, it is common that a researcher has a list of candidate models at hand and a design has to be found…

Statistics Theory · Mathematics 2023-03-29 Mingyao Ai , Holger Dette , Zhengfu Liu , Jun Yu

The doubly-robust (DR) estimator is popular for evaluating causal effects in observational studies and is often perceived as more desirable than inverse probability weighting (IPW) or outcome modeling alone because it provides extra…

Methodology · Statistics 2026-02-03 Chengxin Yang , Laine E. Thomas , Fan Li

In personalized medicine, the ability to predict and optimize treatment outcomes across various time frames is essential. Additionally, the ability to select cost-effective treatments within specific budget constraints is critical. Despite…

Machine Learning · Computer Science 2024-10-14 Thomas Schwarz , Cecilia Casolo , Niki Kilbertus

We develop a probabilistic framework for deep learning based on the Deep Rendering Mixture Model (DRMM), a new generative probabilistic model that explicitly capture variations in data due to latent task nuisance variables. We demonstrate…

Machine Learning · Statistics 2016-12-07 Ankit B. Patel , Tan Nguyen , Richard G. Baraniuk

Body Dysmorphic Disorder (BDD) is a highly prevalent and frequently underdiagnosed condition characterized by persistent, intrusive preoccupations with perceived defects in physical appearance. In this extended analysis, we employ multiple…

Machine Learning · Computer Science 2025-03-17 Omar Costilla-Reyes , Morgan Talbot

Interactive Recommendation (IR) has gained significant attention recently for its capability to quickly capture dynamic interest and optimize both short and long term objectives. IR agents are typically implemented through Deep…

Information Retrieval · Computer Science 2025-06-17 Jingyu Li , Zhiyong Feng , Dongxiao He , Hongqi Chen , Qinghang Gao , Guoli Wu

Precision medicine has the potential to tailor treatment decisions to individual patients using machine learning (ML) and artificial intelligence (AI), but it faces significant challenges due to complex biases in clinical observational data…

Machine Learning · Computer Science 2024-11-26 Michael Vollenweider , Manuel Schürch , Chiara Rohrer , Gabriele Gut , Michael Krauthammer , Andreas Wicki

We consider design issues for toxicology studies when we have a continuous response and the true mean response is only known to be a member of a class of nested models. This class of non-linear models was proposed by toxicologists who were…

Statistics Theory · Mathematics 2010-11-29 Holger Dette , Andrey Pepelyshev , Piter Shpilev , Weng Kee Wong

Click-through rate (CTR) prediction is a critical problem in web search, recommendation systems and online advertisement displaying. Learning good feature interactions is essential to reflect user's preferences to items. Many CTR prediction…

Information Retrieval · Computer Science 2021-05-13 Yuan Cheng , Yanbo Xue

Dynamic regressor selection (DRS) systems work by selecting the most competent regressors from an ensemble to estimate the target value of a given test pattern. This competence is usually quantified using the performance of the regressors…

Machine Learning · Computer Science 2019-08-27 Thiago J. M. Moura , George D. C. Cavalcanti , Luiz S. Oliveira

Evaluation of predictive deep learning (DL) models beyond conventional performance metrics has become increasingly important for applications in sensitive environments like healthcare. Such models might have the capability to encode and…

This paper investigates a specific class of nonsmooth nonconvex optimization problems in the face of data uncertainty, namely, robust optimization problems, where the given objective function can be expressed as a difference of two…

Optimization and Control · Mathematics 2026-02-20 Feryal Mashkoorzadeh , Nooshin Movahedian

Interpretability of AI models allows for user safety checks to build trust in these models. In particular, decision trees (DTs) provide a global view on the learned model and clearly outlines the role of the features that are critical to…

Machine Learning · Computer Science 2023-04-13 Hector Kohler , Riad Akrour , Philippe Preux

We consider the recently introduced application of the Deck of Cards Method (DCM) to ordinal regression proposing two extensions related to two main research trends in Multiple Criteria Decision Aiding, namely scaling and ordinal regression…

Optimization and Control · Mathematics 2025-03-19 Salvatore Corrente , Salvatore Greco , Silvano Zappalá

In modern advertising and recommender systems, multi-task learning (MTL) paradigm has been widely employed to jointly predict diverse user feedbacks (e.g. click and purchase). While, existing MTL approaches are either rigid to adapt to…

Information Retrieval · Computer Science 2023-02-07 Zihan Lin , Xuanhua Yang , Xiaoyu Peng , Wayne Xin Zhao , Shaoguo Liu , Liang Wang , Bo Zheng

Natural language understanding (NLU) models often rely on dataset biases rather than intended task-relevant features to achieve high performance on specific datasets. As a result, these models perform poorly on datasets outside the training…

Computation and Language · Computer Science 2023-01-05 Yougang Lyu , Piji Li , Yechang Yang , Maarten de Rijke , Pengjie Ren , Yukun Zhao , Dawei Yin , Zhaochun Ren

Although neural networks (especially deep neural networks) have achieved \textit{better-than-human} performance in many fields, their real-world deployment is still questionable due to the lack of awareness about the limitation in their…

Machine Learning · Computer Science 2023-04-12 Mehedi Hasan , Moloud Abdar , Abbas Khosravi , Uwe Aickelin , Pietro Lio' , Ibrahim Hossain , Ashikur Rahman , Saeid Nahavandi

Predicting clinical outcomes to anti-cancer drugs on a personalized basis is challenging in cancer treatment due to the heterogeneity of tumors. Traditional computational efforts have been made to model the effect of drug response on…

Machine Learning · Computer Science 2022-07-12 Jie Gao , Jing Hu , Wanqing Sun , Yili Shen , Xiaonan Zhang , Xiaomin Fang , Fan Wang , Guodong Zhao

Previous deep learning approaches for survival analysis have primarily relied on ranking losses to improve discrimination performance, which often comes at the expense of calibration performance. To address such an issue, we propose a novel…

Machine Learning · Computer Science 2024-11-22 Dongjoon Lee , Hyeryn Park , Changhee Lee

The dramatically growing availability of observational data is being witnessed in various domains of science and technology, which facilitates the study of causal inference. However, estimating treatment effects from observational data is…

Machine Learning · Statistics 2021-06-08 Zhixuan Chu , Stephen L. Rathbun , Sheng Li