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Prediction uncertainty estimation has clinical significance as it can potentially quantify prediction reliability. Clinicians may trust 'blackbox' models more if robust reliability information is available, which may lead to more models…

Machine Learning · Computer Science 2022-10-04 Michael Dohopolski , Kai Wang , Biling Wang , Ti Bai , Dan Nguyen , David Sher , Steve Jiang , Jing Wang

Difference-in-differences is a common method for estimating treatment effects, and the parallel trends condition is its main identifying assumption: the trend in mean untreated outcomes is independent of the observed treatment status. In…

Econometrics · Economics 2023-08-09 Philip Marx , Elie Tamer , Xun Tang

Learning from 3D protein structures has gained wide interest in protein modeling and structural bioinformatics. Unfortunately, the number of available structures is orders of magnitude lower than the training data sizes commonly used in…

Biomolecules · Quantitative Biology 2022-06-01 Pedro Hermosilla , Timo Ropinski

Deep Candidate Generation plays an important role in large-scale recommender systems. It takes user history behaviors as inputs and learns user and item latent embeddings for candidate generation. In the literature, conventional methods…

Information Retrieval · Computer Science 2022-11-24 Ningning Li , Qunwei Li , Xichen Ding , Shaohu Chen , Wenliang Zhong

In the area of urban transportation networks, a growing number of day-to-day (DTD) traffic dynamic theories have been proposed to describe the network flow evolution, and an increasing amount of laboratory experiments have been conducted to…

Physics and Society · Physics 2023-03-08 Hang Qi , Ning Jia , Xiaobo Qu , Zhengbing He

Trajectory following is one of the complicated control problems when its dynamics are nonlinear, stochastic and include a large number of parameters. The problem has significant difficulties including a large number of trials required for…

Robotics · Computer Science 2019-02-14 Ali Lenjani

The \textit{de facto} paradigm for applying dense retrieval (DR) to new tasks involves fine-tuning a pre-trained model for a specific task. However, this paradigm has two significant limitations: (1) It is difficult adapt the DR to a new…

Information Retrieval · Computer Science 2026-02-27 Zhan Su , Fengran Mo , Jinghan Zhang , Yuchen Hui , Jia Ao Sun , Bingbing Wen , Jian-Yun Nie

Survival models are used in various fields, such as the development of cancer treatment protocols. Although many statistical and machine learning models have been proposed to achieve accurate survival predictions, little attention has been…

Machine Learning · Computer Science 2020-03-26 Hrushikesh Loya , Pranav Poduval , Deepak Anand , Neeraj Kumar , Amit Sethi

Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

Although the self-supervised pre-training of transformer models has resulted in the revolutionizing of natural language processing (NLP) applications and the achievement of state-of-the-art results with regard to various benchmarks, this…

Computation and Language · Computer Science 2023-01-26 Xiang Chen , Xin Xie , Zhen Bi , Hongbin Ye , Shumin Deng , Ningyu Zhang , Huajun Chen

Diffusion models exhibit excellent sample quality, but existing guidance methods often require additional model training or are limited to specific tasks. We revisit guidance in diffusion models from the perspective of variational inference…

Machine Learning · Computer Science 2025-05-27 Kushagra Pandey , Farrin Marouf Sofian , Felix Draxler , Theofanis Karaletsos , Stephan Mandt

Interfractional geometric uncertainties can lead to deviations of the actual delivered dose from the prescribed dose distribution. To better handle these uncertainties during treatment, the authors propose a dynamic framework for robust…

Medical Physics · Physics 2019-05-16 Michelle Böck , Kjell Eriksson , Anders Forsgren

Existing observational approaches for learning human preferences, such as inverse reinforcement learning, usually make strong assumptions about the observability of the human's environment. However, in reality, people make many important…

Machine Learning · Statistics 2021-10-29 Cassidy Laidlaw , Stuart Russell

Phase II dose finding studies in clinical drug development are typically conducted to adequately characterize the dose response relationship of a new drug. An important decision is then on the choice of a suitable dose response function to…

Applications · Statistics 2015-08-04 Kirsten Schorning , Björn Bornkamp , Frank Bretz , Holger Dette

When an optimal treatment regime (OTR) is considered, we need to evaluate the OTR in a valid and efficient way. The classical inference applied to the mean outcome under OTR, assuming the OTR is the same as the estimated OTR, might be…

Methodology · Statistics 2026-04-21 Shuoxun Xu , Xinzhou Guo

While open sourced Vision-Language Models (VLMs) have proliferated, selecting the optimal pretrained model for a specific downstream task remains challenging. Exhaustive evaluation is often infeasible due to computational constraints and…

Artificial Intelligence · Computer Science 2026-02-03 Wei Yang , Hong Xie , Tao Tan , Xin Li , Defu Lian , Enhong Chen

In real life, we frequently come across data sets that involve some independent explanatory variable(s) generating a set of ordinal responses. These ordinal responses may correspond to an underlying continuous latent variable, which is…

Methodology · Statistics 2024-01-08 Arijit Pyne , Subhrajyoty Roy , Abhik Ghosh , Ayanendranath Basu

Establishing causality is a fundamental goal in fields like medicine and social sciences. While randomized controlled trials are the gold standard for causal inference, they are not always feasible or ethical. Observational studies can…

Statistics Theory · Mathematics 2024-12-03 Andrew Ying

Deep reinforcement learning (DRL) has emerged as a promising approach for developing more intelligent autonomous vehicles (AVs). A typical DRL application on AVs is to train a neural network-based driving policy. However, the black-box…

Artificial Intelligence · Computer Science 2023-05-15 Weitao Zhou , Zhong Cao , Nanshan Deng , Kun Jiang , Diange Yang

The issue of disagreements amongst human experts is a ubiquitous one in both machine learning and medicine. In medicine, this often corresponds to doctor disagreements on a patient diagnosis. In this work, we show that machine learning…

Machine Learning · Computer Science 2019-05-30 Maithra Raghu , Katy Blumer , Rory Sayres , Ziad Obermeyer , Robert Kleinberg , Sendhil Mullainathan , Jon Kleinberg
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