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Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

Computation and Language · Computer Science 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman

Recommender systems utilizing explicit feedback have witnessed significant advancements and widespread applications over the past years. However, generating recommendations in few-shot scenarios remains a persistent challenge. Recently,…

Information Retrieval · Computer Science 2023-12-22 Zhoumeng Wang

Large language models (LLMs) are increasingly deployed to support human decision-making. This use of LLMs has concerning implications, especially when their prescriptions affect the welfare of others. To gauge how LLMs make social…

Computers and Society · Computer Science 2026-01-16 Saptarshi Pal , Abhishek Mallela , Christian Hilbe , Lenz Pracher , Chiyu Wei , Feng Fu , Santiago Schnell , Martin A Nowak

Recent research has explored using Large Language Models for recommendation tasks by transforming user interaction histories and item metadata into text prompts, then having the LLM produce rankings or recommendations. A promising approach…

Information Retrieval · Computer Science 2025-10-03 Bo Ma , LuYao Liu , Simon Lau , Chandler Yuan , and XueY Cui , Rosie Zhang

The emergence of advanced reasoning capabilities in Large Language Models (LLMs) marks a transformative development in healthcare applications. Beyond merely expanding functional capabilities, these reasoning mechanisms enhance decision…

Artificial Intelligence · Computer Science 2025-08-27 Armin Berger , Sarthak Khanna , David Berghaus , Rafet Sifa

Large language models (LLMs) achieve strong average performance yet remain unreliable at the instance level, with frequent hallucinations, brittle failures, and poorly calibrated confidence. We study reliability through the lens of…

Artificial Intelligence · Computer Science 2026-01-13 Pranav Kallem

While pioneering deep learning methods have made great strides in analyzing electronic health record (EHR) data, they often struggle to fully capture the semantics of diverse medical codes from limited data. The integration of external…

Machine Learning · Computer Science 2024-08-26 Zhihao Yu , Yujie Jin , Yongxin Xu , Xu Chu , Yasha Wang , Junfeng Zhao

The rapid evolution of artificial intelligence in drug discovery encounters challenges with generalization and extensive training, yet Large Language Models (LLMs) offer promise in reshaping interactions with complex molecular data. Our…

Biomolecules · Quantitative Biology 2024-12-20 He Cao , Zijing Liu , Xingyu Lu , Yuan Yao , Yu Li

Large Language Models (LLMs) increasingly support applications in a wide range of domains, some with potential high societal impact such as biomedicine, yet their reliability in realistic use cases is under-researched. In this work we…

Large language models (LLMs) have achieved a degree of success in generating coherent and contextually relevant text, yet they remain prone to a significant challenge known as hallucination: producing information that is not substantiated…

Computation and Language · Computer Science 2024-10-28 Ray Li , Tanishka Bagade , Kevin Martinez , Flora Yasmin , Grant Ayala , Michael Lam , Kevin Zhu

Large Language Models (LLMs) are transforming healthcare through the development of LLM-based agents that can understand, reason about, and assist with medical tasks. This survey provides a comprehensive review of LLM-based agents in…

Computation and Language · Computer Science 2025-05-27 Wenxuan Wang , Zizhan Ma , Zheng Wang , Chenghan Wu , Jiaming Ji , Wenting Chen , Xiang Li , Yixuan Yuan

The remarkable performance of large language models (LLMs) in content generation, coding, and common-sense reasoning has spurred widespread integration into many facets of society. However, integration of LLMs raises valid questions on…

Computation and Language · Computer Science 2025-07-03 Ola Shorinwa , Zhiting Mei , Justin Lidard , Allen Z. Ren , Anirudha Majumdar

Simulations, although powerful in accurately replicating real-world systems, often remain inaccessible to non-technical users due to their complexity. Conversely, large language models (LLMs) provide intuitive, language-based interactions…

Computation and Language · Computer Science 2025-05-22 Jacob Kleiman , Kevin Frank , Joseph Voyles , Sindy Campagna

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

Human-Computer Interaction · Computer Science 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

In this study, we introduce PharmacyGPT, a novel framework to assess the capabilities of large language models (LLMs) such as ChatGPT and GPT-4 in emulating the role of clinical pharmacists. Our methodology encompasses the utilization of…

Artificial intelligence (AI) technology has advanced rapidly in recent years, with large language models (LLMs) emerging as a significant breakthrough. LLMs are increasingly making an impact across various industries, with the medical field…

Artificial Intelligence · Computer Science 2025-09-24 Zhiyu Kan , Wensheng Gan , Zhenlian Qi , Philip S. Yu

In human society, trust is an essential component of social attitude that helps build and maintain long-term, healthy relationships which creates a strong foundation for cooperation, enabling individuals to work together effectively and…

Human-Computer Interaction · Computer Science 2025-07-30 Anushka Debnath , Stephen Cranefield , Emiliano Lorini , Bastin Tony Roy Savarimuthu

The development of automated experimental facilities and the digitization of experimental data have introduced numerous opportunities to radically advance chemical laboratories. As many laboratory tasks involve predicting and understanding…

Large language models (LLMs) are increasingly used to provide instructions to many agents who interact with one another. Such shared reliance couples agents who appear to act independently: they may in fact be guided by a common model. This…

Computer Science and Game Theory · Computer Science 2026-05-08 Jonathan Shaki , Eden Hartman , Sarit Kraus , Yonatan Aumann