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In all but special circumstances, measurements of time-dependent processes reflect internal structures and correlations only indirectly. Building predictive models of such hidden information sources requires discovering, in some way, the…

Probability · Mathematics 2009-11-10 Nihat Ay , James P. Crutchfield

Information processing machines at the nanoscales are unavoidably affected by thermal fluctuations. Efficient design requires understanding how nanomachines can operate at minimal energy dissipation. In this letter we focus on mechanical…

Statistical Mechanics · Physics 2015-03-17 Paolo Muratore-Ginanneschi , Kay Schwieger

Collections of self-propelled particles that move persistently by continuously consuming free energy are a paradigmatic example of active matter. In these systems, unlike Brownian "hot colloids", the breakdown of detailed balance yields a…

Soft Condensed Matter · Physics 2018-09-12 Suraj Shankar , M. Cristina Marchetti

Kinetic proofreading mechanisms explain the extraordinary accuracy observed in central biological events in terms of the enhanced specificity of substrate selection networks under a nonequilibrium environment. The nonequilibrium steady…

Adaptation and Self-Organizing Systems · Physics 2022-06-29 Premashis Kumar , Kinshuk Banerjee , Gautam Gangopadhyay

Physical dynamical systems can be viewed as natural information processors: their systems preserve, transform, and disperse input information. This perspective motivates learning not only from data generated by such systems, but also how to…

Machine Learning · Computer Science 2026-03-05 Felix Köster , Atsushi Uchida

Active matter and driven systems exhibit statistical fluctuations in density and particle positions, providing an indirect indicator of dissipation across multiple length and time scales. Here, we quantitatively relate these measurable…

Statistical Mechanics · Physics 2024-12-19 Aishani Ghosal , Jason R. Green

Observations with distributed sensors are essential in analyzing a series of human and machine activities (referred to as 'events' in this paper) in complex and extensive real-world environments. This is because the information obtained…

Multimedia · Computer Science 2024-04-15 Masahiro Yasuda , Noboru Harada , Yasunori Ohishi , Shoichiro Saito , Akira Nakayama , Nobutaka Ono

In this paper, we wish to investigate the dynamics of information transfer in evolutionary dynamics. We use information theoretic tools to track how much information an evolving population has obtained and managed to retain about different…

Populations and Evolution · Quantitative Biology 2021-04-09 Nicholas Guttenberg

Molecular simulations and biophysical experiments can be used to provide independent and complementary insights into the molecular origin of biological processes. A particularly useful strategy is to use molecular simulations as a modelling…

Chemical Physics · Physics 2019-12-10 Simone Orioli , Andreas Haahr Larsen , Sandro Bottaro , Kresten Lindorff-Larsen

In macroscopic systems behavior is usually reproducible and fluctuations, which are deviations from the typically observed mean values, are small. But almost all inverse problems in the physical and biological sciences are ill-posed and…

Statistical Mechanics · Physics 2017-08-09 Peter Burgholzer

Current developments in molecular electronics, motors and chemical sensors could enable constructing large numbers of devices able to sense, compute and act in micron-scale environments. Such microscopic machines, of sizes comparable to…

Robotics · Computer Science 2023-02-03 Tad Hogg

The influence of dissipation on the fluctuation statistics of the total energy is investigated through both a phenomenological and a stochastic model for dissipative energy-transfer through a cascade of states. In equilibrium the states…

Statistical Mechanics · Physics 2013-06-27 Eric Bertin , Peter C. W. Holdsworth

Directional chemosensing is ubiquitous in cell biology, but some cells such as mating yeast paradoxically degrade the signal they aim to detect. While the data processing inequality suggests that such signal modification cannot increase the…

Biological Physics · Physics 2023-10-04 Ryan LeFebre , Joseph A. Landsittel , David E. Stone , Andrew Mugler

In this article, we describe a new method of extracting information from signals, called functional dissipation, that proves to be very effective for enhancing classification of high resolution, texture-rich data. Our algorithm bypasses to…

Data Analysis, Statistics and Probability · Physics 2012-06-15 D. Napoletani , D. C. Struppa , T. Sauer , V. Morozov , N. Vsevolodov , C. Bailey

Signaling networks are designed to sense an environmental stimulus and adapt to it. We propose and study a minimal model of signaling network that can sense and respond to external stimuli of varying strength in an adaptive manner. The…

Molecular Networks · Quantitative Biology 2010-09-14 Subhadip Raychaudhuri

Environmental fluctuations can shape replicator dynamics, with important consequences for both prebiotic and modern ecosystems. However, it remains unclear how simple replicators can acquire and use information about fluctuating…

Biological Physics · Physics 2026-05-25 Jordi Piñero , Damian R. Sowinski , Gourab Ghoshal , Adam Frank , Artemy Kolchinsky

Quantum information processing relies on precise control of non-classical states in the presence of many uncontrolled environmental degrees of freedom -- requiring careful orchestration of how the relevant degrees of freedom interact with…

Quantum Physics · Physics 2024-02-06 Patrick M. Harrington , Erich Mueller , Kater Murch

Inferring the directionality of interactions between cellular processes is a major challenge in systems biology. Time-lagged correlations allow to discriminate between alternative models, but they still rely on assumed underlying…

Quantitative Methods · Quantitative Biology 2017-11-15 Sourabh Lahiri , Philippe Nghe , Sander J. Tans , Martin Luc Rosinberg , David Lacoste

This paper presents a practical writing/reading scheme in nonvolatile memories, called balanced modulation, for minimizing the asymmetric component of errors. The main idea is to encode data using a balanced error-correcting code. When…

Information Theory · Computer Science 2012-09-05 Hongchao Zhou , Anxiao , Jiang , Jehoshua Bruck

In various biological systems information from many noisy molecular receptors must be integrated into a collective response. A striking example is the thermal imaging organ of pit vipers. Single nerve fibers in the organ reliably respond to…

Biological Physics · Physics 2024-05-31 Isabella R. Graf , Benjamin B. Machta
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