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To achieve minimum DNA input and tumor purity requirements for next-generation sequencing (NGS), pathologists visually estimate macrodissection and slide count decisions. Misestimation may cause tissue waste and increased laboratory costs.…

Artificial intelligence (AI) solutions that automatically extract information from digital histology images have shown great promise for improving pathological diagnosis. Prior to routine use, it is important to evaluate their predictive…

Real-time computer-aided diagnosis using artificial intelligence (AI), with images, can help oncologists diagnose cancer with high accuracy and in an early phase. We reviewed real-time AI-based analyzed images for decision-making in…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Leila Bagheriye , Johan Kwisthout

Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for…

Quantitative Methods · Quantitative Biology 2024-12-17 Suchithra Kunhoth , Somaya Al- Maadeed , Younes Akbari , Rafif Al Saady

The importance of rapid and accurate histologic analysis of surgical tissue in the operating room has been recognized for over a century. Our standard-of-care intraoperative pathology workflow is based on light microscopy and H\&E…

Despite the promises of data-driven artificial intelligence (AI), little is known about how we can bridge the gulf between traditional physician-driven diagnosis and a plausible future of medicine automated by AI. Specifically, how can we…

Human-Computer Interaction · Computer Science 2021-02-12 Hongyan Gu , Jingbin Huang , Lauren Hung , Xiang 'Anthony' Chen

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

Recent advances in whole slide imaging (WSI) technology have led to the development of a myriad of computer vision and artificial intelligence (AI) based diagnostic, prognostic, and predictive algorithms. Computational Pathology (CPath)…

The use of artificial intelligence to enable precision medicine and decision support systems through the analysis of pathology images has the potential to revolutionize the diagnosis and treatment of cancer. Such applications will depend on…

Immunohistochemistry (IHC) provides information on protein expression in tissue sections and is commonly used to support pathology diagnosis and disease triage. While AI models for H\&E-stained slides show promise, their applicability to…

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem…

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

Image and Video Processing · Electrical Eng. & Systems 2023-02-10 John-Melle Bokhorst , Iris D. Nagtegaal , Filippo Fraggetta , Simona Vatrano , Wilma Mesker , Michael Vieth , Jeroen van der Laak , Francesco Ciompi

Efficient and effective assessment of acute and chronic wounds can help wound care teams in clinical practice to greatly improve wound diagnosis, optimize treatment plans, ease the workload and achieve health related quality of life to the…

Computers and Society · Computer Science 2021-10-13 D. M. Anisuzzaman , Chuanbo Wang , Behrouz Rostami , Sandeep Gopalakrishnan , Jeffrey Niezgoda , Zeyun Yu

Continual learning is rapidly emerging as a key focus in computer vision, aiming to develop AI systems capable of continuous improvement, thereby enhancing their value and practicality in diverse real-world applications. In healthcare,…

Recent developments in AI have provided assisting tools to support pathologists' diagnoses. However, it remains challenging to incorporate such tools into pathologists' practice; one main concern is AI's insufficient workflow integration…

Advances in AI have introduced several strong models in computational pathology to usher it into the era of multi-modal diagnosis, analysis, and interpretation. However, the current pathology-specific visual language models still lack…

Accurate semantic segmentation for histopathology image is crucial for quantitative tissue analysis and downstream clinical modeling. Recent segmentation foundation models have improved generalization through large-scale pretraining, yet…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Peixian Liang , Songhao Li , Shunsuke Koga , Yutong Li , Zahra Alipour , Yucheng Tang , Daguang Xu , Zhi Huang

Deep learning methods have emerged as powerful tools for analyzing histopathological images, but current methods are often specialized for specific domains and software environments, and few open-source options exist for deploying models in…

Digital pathology plays a vital role across modern medicine, offering critical insights for disease diagnosis, prognosis, and treatment. However, histopathology images often contain artifacts introduced during slide preparation and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Zhenzhen Wang , Zhongliang Zhou , Zhuoyu Wen , Jeong Hwan Kook , John B Wojcik , John Kang

Pathologists diagnose cancer using gigapixel whole-slide images (WSIs), but the current digital workflow is fragmented. These multiscale datasets often exceed 100,000 x 100,000 pixels, yet standard 2D monitors restrict the field of view.…

Human-Computer Interaction · Computer Science 2026-02-27 Jai Prakash Veerla , Partha Sai Guttikonda , Helen H. Shang , Mohammad Sadegh Nasr , Cesar Torres , Jacob M. Luber