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Large language models (LLMs) have shown growing promise in biomedical research, particularly for knowledge-driven interpretation tasks. However, their ability to reliably reason from gene-level knowledge to functional understanding, a core…

Genomics · Quantitative Biology 2026-05-25 Xiaohan Huang , Meng Xiao , Chuan Qin , Qingqing Long , Jinmiao Chen , Yuanchun Zhou , Hengshu Zhu

LLM watermarking, which embeds imperceptible yet algorithmically detectable signals in model outputs to identify LLM-generated text, has become crucial in mitigating the potential misuse of large language models. However, the abundance of…

Cryptography and Security · Computer Science 2024-10-29 Leyi Pan , Aiwei Liu , Zhiwei He , Zitian Gao , Xuandong Zhao , Yijian Lu , Binglin Zhou , Shuliang Liu , Xuming Hu , Lijie Wen , Irwin King , Philip S. Yu

While Large Language Models (LLMs) have demonstrated proficiency in Deep Research or Wide Search, their capacity to solve highly complex questions-those requiring long-horizon planning, massive evidence gathering, and synthesis across…

Computation and Language · Computer Science 2026-03-04 Yubo Dong , Nianhao You , Yuxuan Hou , Zixun Sun , Yue Zhang , Liang Zhang , Siyuan Zhao , Hehe Fan

Ontology learning in complex domains, such as life sciences, poses significant challenges for current Large Language Models (LLMs). Existing LLMs struggle to generate ontologies with multiple hierarchical levels, rich interconnections, and…

Artificial Intelligence · Computer Science 2024-12-04 Nadeen Fathallah , Steffen Staab , Alsayed Algergawy

The performance of Large Language Models (LLMs) is fundamentally determined by the contextual information provided during inference. This survey introduces Context Engineering, a formal discipline that transcends simple prompt design to…

The remarkable achievements of Artificial Intelligence (AI) algorithms, particularly in Machine Learning (ML) and Deep Learning (DL), have fueled their extensive deployment across multiple sectors, including Software Engineering (SE).…

Software Engineering · Computer Science 2025-02-06 Sicong Cao , Xiaobing Sun , Ratnadira Widyasari , David Lo , Xiaoxue Wu , Lili Bo , Jiale Zhang , Bin Li , Wei Liu , Di Wu , Yixin Chen

Predictive analysis is a cornerstone of modern decision-making, with applications in various domains. Large Language Models (LLMs) have emerged as powerful tools in enabling nuanced, knowledge-intensive conversations, thus aiding in complex…

Computation and Language · Computer Science 2025-05-26 Qin Chen , Yuanyi Ren , Xiaojun Ma , Yuyang Shi

Large language models (LLMs) have revolutionized natural language processing with their exceptional understanding, synthesizing, and reasoning capabilities. However, deploying LLMs on resource-constrained edge devices presents significant…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-25 Yue Zheng , Yuhao Chen , Bin Qian , Xiufang Shi , Yuanchao Shu , Jiming Chen

Large Language Models (LLMs) have achieved remarkable success across diverse applications, yet their deployment remains challenging due to substantial computational costs, memory requirements, and energy consumption. Recent empirical…

Machine Learning · Computer Science 2026-03-24 Kaito Tanaka , Masato Ito , Yuji Nishimura , Keisuke Matsuda , Aya Nakayama

In recent years, large language models (LLMs) have demonstrated strong performance on multilingual tasks. Given its wide range of applications, cross-cultural understanding capability is a crucial competency. However, existing benchmarks…

Computation and Language · Computer Science 2025-12-09 Shiwei Guo , Sihang Jiang , Qianxi He , Yanghua Xiao , Jiaqing Liang , Bi Yude , Minggui He , Shimin Tao , Li Zhang

The rapid growth of Large Language Models (LLMs) has been a driving force in transforming various domains, reshaping the artificial general intelligence landscape. However, the increasing computational and memory demands of these models…

Computation and Language · Computer Science 2024-04-22 Tianyu Ding , Tianyi Chen , Haidong Zhu , Jiachen Jiang , Yiqi Zhong , Jinxin Zhou , Guangzhi Wang , Zhihui Zhu , Ilya Zharkov , Luming Liang

Requirements engineering is a knowledge intensive process and crucial for the success of engineering projects. The field of knowledge-based requirements engineering (KBRE) aims to support engineers by providing knowledge to assist in the…

Software Engineering · Computer Science 2024-11-19 Lasse M. Reinpold , Marvin Schieseck , Lukas P. Wagner , Felix Gehlhoff , Alexander Fay

Recently, the remarkable success of large language models (LLMs) has achieved a profound impact on the field of artificial intelligence. Numerous advanced works based on LLMs have been proposed and applied in various scenarios. Among them,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Xizhe Xue , Yang Zhou , Dawei Yan , Lijie Tao , Junjie Li , Ying Li , Haokui Zhang , Rong Xiao

Large language models (LLMs) have demonstrated remarkable capabilities across a wide range of tasks in various domains. Despite their impressive performance, they can be unreliable due to factual errors in their generations. Assessing their…

Computation and Language · Computer Science 2024-03-26 Jiahui Geng , Fengyu Cai , Yuxia Wang , Heinz Koeppl , Preslav Nakov , Iryna Gurevych

This work presents an ontology-integrated large language model (LLM) framework for chemical engineering that unites structured domain knowledge with generative reasoning. The proposed pipeline aligns model training and inference with the…

Machine Learning · Computer Science 2025-12-15 Crystal Su , Kuai Yu , Jingrui Zhang , Mingyuan Shao , Daniel Bauer

As large language models (LLMs) are increasingly applied to scientific reasoning, the complexity of answer formats and the diversity of equivalent expressions make answer verification a critical yet challenging task. Existing verification…

Artificial Intelligence · Computer Science 2025-09-30 Shenghe Zheng , Chenyu Huang , Fangchen Yu , Junchi Yao , Jingqi Ye , Tao Chen , Yun Luo , Ning Ding , LEI BAI , Ganqu Cui , Peng Ye

Current benchmarks for evaluating the chemical reasoning capabilities of Large Language Models (LLMs) are limited by oversimplified tasks, lack of process-level evaluation, and misalignment with expert-level chemistry skills. To address…

The rapid expansion of English technical terminology presents a significant challenge to traditional expert-based standardization, particularly in rapidly developing areas such as artificial intelligence and quantum computing. Manual…

Computation and Language · Computer Science 2025-06-12 Li Weigang , Pedro Carvalho Brom

Context. Large language models (LLMs) are increasingly applied to code-generating tasks (CGTs) in software engineering. While reported results are promising, the broader effects of such application and their integration into real-world…

Software Engineering · Computer Science 2026-05-26 Muslim Chochlov , Michael English , Jim Buckley

Despite recent advances in large language models (LLMs) for materials science, there is a lack of benchmarks for evaluating their domain-specific knowledge and complex reasoning abilities. To bridge this gap, we introduce MSQA, a…

Artificial Intelligence · Computer Science 2025-06-02 Jerry Junyang Cheung , Shiyao Shen , Yuchen Zhuang , Yinghao Li , Rampi Ramprasad , Chao Zhang