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Related papers: COPE: Chain-Of-Thought Prediction Engine for Open-…

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Objective Structured Clinical Examinations (OSCEs) are widely used to assess medical students' communication skills, but scoring interview-based assessments is time-consuming and potentially subject to human bias. This study explored the…

Computation and Language · Computer Science 2025-05-16 Jadon Geathers , Yann Hicke , Colleen Chan , Niroop Rajashekar , Justin Sewell , Susannah Cornes , Rene F. Kizilcec , Dennis Shung

Addressing the challenge of multimodal data fusion in high-dimensional biomedical informatics, we propose MMCTOP, a MultiModal Clinical-Trial Outcome Prediction framework that integrates heterogeneous biomedical signals spanning (i)…

Machine Learning · Computer Science 2025-12-29 Carolina Aparício , Qi Shi , Bo Wen , Tesfaye Yadete , Qiwei Han

Electronic health records (EHRs) enable strong clinical prediction, but explanations are often coarse and hard to use for patient-level decisions. We propose a knowledge graph (KG)-guided chain-of-thought (CoT) framework for visit-level…

Artificial Intelligence · Computer Science 2026-03-03 Ruiyu Wang , Tuan Vinh , Ran Xu , Yuyin Zhou , Jiaying Lu , Carl Yang , Francisco Pasquel

Few-shot Chain-of-Thought (CoT) prompting has demonstrated strong performance in improving the reasoning capabilities of large language models (LLMs). While theoretical investigations have been conducted to understand CoT, the underlying…

Computation and Language · Computer Science 2024-10-23 Yingqian Cui , Pengfei He , Xianfeng Tang , Qi He , Chen Luo , Jiliang Tang , Yue Xing

As large language models empower healthcare, intelligent clinical decision support has developed rapidly. Longitudinal electronic health records (EHR) provide essential temporal evidence for accurate clinical diagnosis and analysis.…

Computation and Language · Computer Science 2026-05-15 Zihan Deng , Xiaozhen Zhong , Chuanzhi Xu

The objective of this work is to develop an Electronic Medical Record (EMR) data processing tool that confers clinical context to Machine Learning (ML) algorithms for error handling, bias mitigation and interpretability. We present…

Reasoning large language models (LLMs) have demonstrated superior capacities in solving complicated problems by generating long chain-of-thoughts (CoT), but such a lengthy CoT incurs high inference costs. Previous methods on inference-stage…

Computation and Language · Computer Science 2026-05-19 Minjia Mao , Bowen Yin , Yu Zhu , Xiao Fang

Chain-of-thought and more broadly test-time compute are known to augment the expressive capabilities of language models and have led to major innovations in reasoning. Motivated by this success, this paper explores latent chain-of-thought…

Machine Learning · Computer Science 2026-05-20 Carson Dudley , Samet Oymak

As one of the leading causes of mortality and disability worldwide, Acute Ischemic Stroke (AIS) occurs when the blood supply to the brain is suddenly interrupted because of a blocked artery. Within seconds of AIS onset, the brain cells…

Image and Video Processing · Electrical Eng. & Systems 2022-11-17 Mohsen Soltanpour , Muhammad Yousefnezhad , Russ Greiner , Pierre Boulanger , Brian Buck

Prompt optimization has often been framed as a discrete search problem to find high-performing and robust instructions for an LLM. However, the search result might not make it transparent why and where specific prompt changes lead to…

Computation and Language · Computer Science 2026-05-28 Jiahui Li , Yarik Menchaca Resendiz , Sean Papay , Roman Klinger

We study clinical trial table reasoning, where answers are not directly stored in visible cells but must be reasoned from semantic understanding through normalization, classification, extraction, or lightweight domain reasoning. Motivated…

An automatically differentiable, high-order non-oscillatory finite volume shallow water dynamic core has been constructed on a cubed sphere grid. This dynamic core has four advantageous properties: high order accuracy, essential…

Fluid Dynamics · Physics 2025-01-03 Lilong Zhou

Failure is common in clinical trials since the successful failures presented in negative results always indicate the ways that should not be taken. In this paper, we proposed an automated approach to extracting positive and negative…

Information Retrieval · Computer Science 2022-12-08 Xuanyu Shi , Shiyao Xie , Wenjia Wang , Ting Chen , Jian Du

Chain-of-Thought (CoT) prompting has been shown to enhance the multi-step reasoning capabilities of Large Language Models (LLMs). However, debates persist about whether LLMs exhibit abstract generalization or rely on shallow heuristics when…

Computation and Language · Computer Science 2024-10-07 Akshara Prabhakar , Thomas L. Griffiths , R. Thomas McCoy

Chain-of-Thought(CoT) prompting and its variants explore equipping large language models (LLMs) with high-level reasoning abilities by emulating human-like linear cognition and logic. However, the human mind is complicated and mixed with…

Computation and Language · Computer Science 2023-11-16 Yongqi Tong , Yifan Wang , Dawei Li , Sizhe Wang , Zi Lin , Simeng Han , Jingbo Shang

Chain of Thought (CoT) is significant in improving the reasoning abilities of large language models (LLMs). However, the correlation between the effectiveness of CoT and the length of reasoning steps in prompts remains largely unknown. To…

Computation and Language · Computer Science 2024-06-25 Mingyu Jin , Qinkai Yu , Dong Shu , Haiyan Zhao , Wenyue Hua , Yanda Meng , Yongfeng Zhang , Mengnan Du

Intracerebral hemorrhage (ICH) is the second most common and deadliest form of stroke. Despite medical advances, predicting treat ment outcomes for ICH remains a challenge. This paper proposes a novel prognostic model that utilizes both…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Wenao Ma , Cheng Chen , Jill Abrigo , Calvin Hoi-Kwan Mak , Yuqi Gong , Nga Yan Chan , Chu Han , Zaiyi Liu , Qi Dou

This study presents a fully automated methodology for early prediction studies in clinical settings, leveraging information extracted from unstructured discharge reports. The proposed pipeline uses discharge reports to support the three…

Using Large Language Models for complex mathematical reasoning is difficult, primarily due to the complexity of multi-step reasoning. The main challenges of this process include (1) selecting critical intermediate results to advance the…

Artificial Intelligence · Computer Science 2024-02-29 Zilong Zhao , Yao Rong , Dongyang Guo , Emek Gözlüklü , Emir Gülboy , Enkelejda Kasneci

Ischemic stroke is a severe condition caused by the blockage of brain blood vessels, and can lead to the death of brain tissue due to oxygen deprivation. Thrombectomy has become a common treatment choice for ischemic stroke due to its…

Image and Video Processing · Electrical Eng. & Systems 2024-08-05 Caiwen Jiang , Tianyu Wang , Xiaodan Xing , Mianxin Liu , Guang Yang , Zhongxiang Ding , Dinggang Shen