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Related papers: COPE: Chain-Of-Thought Prediction Engine for Open-…

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Chain-of-thought (CoT) traces are increasingly used both to improve language model capability and to audit model behavior, implicitly assuming that the visible trace remains synchronized with the computation that determines the answer. We…

Artificial Intelligence · Computer Science 2026-05-13 Wenkai Li , Fan Yang , Ananya Hazarika , Shaunak A. Mehta , Koichi Onoue

Empathetic dialogue is crucial for natural human-computer interaction, allowing the dialogue system to respond in a more personalized and emotionally aware manner, improving user satisfaction and engagement. The emergence of large language…

Computation and Language · Computer Science 2025-01-22 Jingran Xie , Shun Lei , Yue Yu , Yang Xiang , Hui Wang , Xixin Wu , Zhiyong Wu

Large Language Models (LLMs) can achieve inflated scores on multiple-choice tasks by exploiting inherent biases in option positions or labels, rather than demonstrating genuine understanding. This study introduces SCOPE, an evaluation…

Computation and Language · Computer Science 2025-08-05 Wonjun Jeong , Dongseok Kim , Taegkeun Whangbo

Coronary artery disease remains one of the leading causes of mortality globally. Despite advances in revascularization treatments like PCI and CABG, postoperative stroke is inevitable. This study aims to develop and evaluate a sophisticated…

Machine Learning · Computer Science 2025-03-18 Haonan Pan , Shuheng Chen , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

We present Chain of Simulation (CoS), a novel dual-mode reasoning framework that dynamically routes problems to specialized reasoning strategies in Large Language Models (LLMs). Unlike existing uniform prompting approaches, CoS employs…

Artificial Intelligence · Computer Science 2026-02-04 Saeid Sheikhi

The medical adoption of NLP tools requires interpretability by end users, yet traditional explainable AI (XAI) methods are misaligned with clinical reasoning and lack clinician input. We introduce CHiRPE (Clinical High-Risk Prediction with…

Recent advances in large language models (LLMs) have shown that Chain-of-Thought (CoT) reasoning can substantially improve performance on complex reasoning tasks. At the same time, In-Context Learning (ICL) has become an important mechanism…

Computation and Language · Computer Science 2026-05-19 Rui Chu

Chain-of-Thought (CoT) reasoning has proven effective in enhancing large language models by encouraging step-by-step intermediate reasoning, and recent advances have extended this paradigm to Multimodal Large Language Models (MLLMs). In the…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Juntao Jiang , Jiangning Zhang , Yali Bi , Jinsheng Bai , Weixuan Liu , Weiwei Jin , Zhucun Xue , Yong Liu , Xiaobin Hu , Shuicheng Yan

New medical treatment development requires multiple phases of clinical trials. Despite the significant human and financial costs of bringing a drug to market, less than 20% of drugs in testing will make it from the first phase to final…

Computation and Language · Computer Science 2024-08-21 Michael Reinisch , Jianfeng He , Chenxi Liao , Sauleh Ahmad Siddiqui , Bei Xiao

Large Language Models (LLMs) are increasingly deployed in medical settings, yet their sensitivity to prompt formatting remains poorly characterized. We evaluate MedGemma (4B and 27B parameters) on MedMCQA (4,183 questions) and PubMedQA…

Computation and Language · Computer Science 2026-03-30 Binesh Sadanandan , Vahid Behzadan

Postoperative stroke remains a critical complication in elderly surgical intensive care unit (SICU) patients, contributing to prolonged hospitalization, elevated healthcare costs, and increased mortality. Accurate early risk stratification…

Quantitative Methods · Quantitative Biology 2025-06-05 Tinghuan Li , Shuheng Chen , Junyi Fan , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Recent advances in reasoning-focused Large Language Models (LLMs) have introduced Chain-of-Thought (CoT) traces - intermediate reasoning steps generated before a final answer. These traces, as in DeepSeek R1, guide inference and train…

Computation and Language · Computer Science 2026-04-20 Siddhant Bhambri , Upasana Biswas , Subbarao Kambhampati

Large language models show improved downstream task performance when prompted to generate step-by-step reasoning to justify their final answers. These reasoning steps greatly improve model interpretability and verification, but objectively…

Computation and Language · Computer Science 2023-09-13 Olga Golovneva , Moya Chen , Spencer Poff , Martin Corredor , Luke Zettlemoyer , Maryam Fazel-Zarandi , Asli Celikyilmaz

Recently, large language models (LLMs) have demonstrated strong performance, ranging from simple to complex tasks. However, while large models achieve remarkable results across diverse tasks, they often incur substantial monetary inference…

Artificial Intelligence · Computer Science 2026-05-12 Byeongchan Lee , Jonghoon Lee , Dongyoung Kim , Jaehyung Kim , Kyungjoon Park , Dongjun Lee , Jinwoo Shin

Although Chain-of-Thought (CoT) has achieved remarkable success in enhancing the reasoning ability of large language models (LLMs), the mechanism of CoT remains a ``black box''. Even if the correct answers can frequently be obtained,…

Machine Learning · Computer Science 2025-02-26 Jiarun Fu , Lizhong Ding , Hao Li , Pengqi Li , Qiuning Wei , Xu Chen

Objective: Post-traumatic epilepsy (PTE) is a debilitating neurological disorder that develops after traumatic brain injury (TBI). Early prediction of PTE remains challenging due to heterogeneous clinical data, limited positive cases, and…

Machine Learning · Computer Science 2026-04-17 Wenhui Cui , Nicholas Swingle , Anand A. Joshi , Dileep Nair , Richard M. Leahy

Accurate prediction of human behavior is essential for robust and safe human-AI collaboration. However, existing approaches for modeling people are often data-hungry and brittle because they either make unrealistic assumptions about…

Artificial Intelligence · Computer Science 2025-10-03 Kunal Jha , Aydan Yuenan Huang , Eric Ye , Natasha Jaques , Max Kleiman-Weiner

Mental health issues among college students have reached critical levels, significantly impacting academic performance and overall wellbeing. Predicting and understanding mental health status among college students is challenging due to…

Machine Learning · Computer Science 2025-06-11 Meghna Roy Chowdhury , Wei Xuan , Shreyas Sen , Yixue Zhao , Yi Ding

Accurate tumor analysis is central to clinical radiology and precision oncology, where early detection, reliable lesion characterization, and pathology-level risk assessment guide diagnosis and treatment planning. Chain-of-Thought (CoT)…