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Length of stay (LOS) prediction in acute stroke is critical for improving care planning. Existing machine learning models have shown suboptimal predictive performance, limited generalisability, and have overlooked system-level factors. We…

Machine Learning · Computer Science 2025-06-17 Zhenran Xu

Accurate prediction of functional outcomes after acute ischemic stroke can inform clinical decision-making and resource allocation. Prior work on modified Rankin Scale (mRS) prediction has relied primarily on structured variables (e.g.,…

We developed a voice-driven artificial intelligence (AI) system that guides anyone - from paramedics to family members - through expert-level stroke evaluations using natural conversation, while also enabling smartphone video capture of key…

Mechanical thrombectomy has become the standard of care in patients with stroke due to large vessel occlusion (LVO). However, only 50% of successfully treated patients show a favorable outcome. We developed and evaluated interpretable deep…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Lisa Herzog , Pascal Bühler , Ezequiel de la Rosa , Beate Sick , Susanne Wegener

Clinical trials are essential to drug development but time-consuming, costly, and prone to failure. Accurate trial outcome prediction based on historical trial data promises better trial investment decisions and more trial success. Existing…

Machine Learning · Computer Science 2023-04-12 Zifeng Wang , Cao Xiao , Jimeng Sun

Background: Widespread adoption of electronic health records (EHRs) has enabled secondary use of EHR data for clinical research and healthcare delivery. Natural language processing (NLP) techniques have shown promise in their capability to…

Information Retrieval · Computer Science 2021-06-15 Sijia Liu , Yanshan Wang , Andrew Wen , Liwei Wang , Na Hong , Feichen Shen , Steven Bedrick , William Hersh , Hongfang Liu

Objective: To improve the efficiency of medical question answering (MedQA) with large language models (LLMs) by avoiding unnecessary reasoning while maintaining accuracy. Methods: We propose Selective Chain-of-Thought (Selective CoT), an…

Computation and Language · Computer Science 2026-02-24 Zaifu Zhan , Min Zeng , Shuang Zhou , Yiran Song , Xiaoyi Chen , Yu Hou , Yifan Wu , Yang Ruan , Rui Zhang

Chain-of-Thought (CoT) prompting has marked a significant advancement in enhancing the reasoning capabilities of large language models (LLMs). Previous studies have developed various extensions of CoT, which focus primarily on enhancing…

Computation and Language · Computer Science 2025-05-20 Xin Xu , Shizhe Diao , Can Yang , Yang Wang

Large language models (LLMs) are increasingly being applied to clinical care, a domain where both accuracy and transparent reasoning are critical for safe and trustworthy deployment. Chain-of-thought (CoT) prompting, which elicits…

Computation and Language · Computer Science 2025-12-09 Jiageng Wu , Kevin Xie , Bowen Gu , Nils Krüger , Kueiyu Joshua Lin , Jie Yang

Covariate adjustment is a ubiquitous method used to estimate the average treatment effect (ATE) from observational data. Assuming a known graphical structure of the data generating model, recent results give graphical criteria for optimal…

Statistics Theory · Mathematics 2025-12-08 Alexander Mangulad Christgau , Anton Rask Lundborg , Niels Richard Hansen

Background and Purpose: We aimed to develop and evaluate an automatic acute ischemic stroke-related (AIS) detection system involving a two-stage deep learning model. Methods: We included 238 cases from two different institutions.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Mizuho Nishio , Sho Koyasu , Shunjiro Noguchi , Takao Kiguchi , Kanako Nakatsu , Thai Akasaka , Hiroki Yamada , Kyo Itoh

The Chain-of-Thought (CoT) paradigm has emerged as a critical approach for enhancing the reasoning capabilities of large language models (LLMs). However, despite their widespread adoption and success, CoT methods often exhibit instability…

Artificial Intelligence · Computer Science 2024-09-06 Yu Wang , Shiwan Zhao , Zhihu Wang , Heyuan Huang , Ming Fan , Yubo Zhang , Zhixing Wang , Haijun Wang , Ting Liu

Accurate short-term mobile traffic prediction is important for proactive resource allocation and low-latency network management in fifth generation (5G) and sixth generation (6G). While large language models (LLMs) can perform in-context…

Networking and Internet Architecture · Computer Science 2026-05-12 MohammadMahdi Ghadaksaz , Mohammad Farzanullah , Akram Bin Sediq , Ali Afana , Melike Erol-Kantarci

Creating high-quality clinical Chains-of-Thought (CoTs) is crucial for explainable medical Artificial Intelligence (AI) while constrained by data scarcity. Although Large Language Models (LLMs) can synthesize medical data, their clinical…

Artificial Intelligence · Computer Science 2025-10-21 Dou Liu , Ying Long , Sophia Zuoqiu , Di Liu , Kang Li , Yiting Lin , Hanyi Liu , Rong Yin , Tian Tang

Computed Tomography (CT) is commonly used to image acute ischemic stroke (AIS) patients, but its interpretation by radiologists is time-consuming and subject to inter-observer variability. Deep learning (DL) techniques can provide automated…

Image and Video Processing · Electrical Eng. & Systems 2023-10-02 Alessandro Fontanella , Wenwen Li , Grant Mair , Antreas Antoniou , Eleanor Platt , Paul Armitage , Emanuele Trucco , Joanna Wardlaw , Amos Storkey

Large language models (LLMs) are increasingly used as judges to replace costly human preference labels in pairwise evaluation. Despite their practicality, LLM judges remain prone to miscalibration and systematic biases. This paper proposes…

Computation and Language · Computer Science 2026-02-20 Sher Badshah , Ali Emami , Hassan Sajjad

Patient outcome prediction is critical in management of ischemic stroke. In this paper, a novel machine learning model is proposed for stroke outcome prediction using multimodal Magnetic Resonance Imaging (MRI). The proposed model consists…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Nima Hatami , Laura Mechtouff , David Rousseau , Tae-Hee Cho , Omer Eker , Yves Berthezene , Carole Frindel

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

This work presents a novel and promising approach to the clinical management of acute stroke. Using machine learning techniques, our research has succeeded in developing accurate diagnosis and prediction real-time models from hemodynamic…

Signal Processing · Electrical Eng. & Systems 2023-06-09 Luis García-Terriza , José L. Risco-Martín , Gemma Reig Roselló , José L. Ayala
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