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How the geometry of nano-sized confinement affects dynamics of biomaterials is interesting yet poorly understood. An elucidation of structural details upon nano-sized confinement may benefit manufacturing pharmaceuticals in biomaterial…

Biological Physics · Physics 2015-05-13 Shao-Qing Zhang , Margaret S. Cheung

In densely-packed two-dimensional systems of growing cells, such as rod-shaped bacteria, a number of experimental and numerical studies report distinct patterns of nematic orientational order in the presence of confinement. So far, these…

Soft Condensed Matter · Physics 2025-06-13 Lukas Hupe , Jonas Isensee , Ramin Golestanian , Philip Bittihn

The coexistence of multiple types of interactions within social, technological and biological networks has moved the focus of the physics of complex systems towards a multiplex description of the interactions between their constituents.…

Physics and Society · Physics 2015-11-09 Jesús Gómez-Gardeñes , Manlio De Domenico , Gerardo Gutiérrez , Alex Arenas , Sergio Gómez

This study investigates the role of spatial segregation, prompted by competition avoidance, as a key mechanism for emergent coexistence within microbial communities. Recognizing these communities as complex adaptive systems, we challenge…

Physics and Society · Physics 2024-03-12 Mattia Mattei , Alex Arenas

Cell size is a fundamental determinant of cellular physiology, influencing processes such as growth, division, and function. In this study, we develop a segmented mathematical framework to investigate how different control mechanisms…

Cell Behavior · Quantitative Biology 2026-02-02 Shuqi Fan , Yuhang Zhang , Jinzhi Lei

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

It has recently been proposed that proteins embedded in lipidic bio-membranes can spontaneously self-organize into stable small clusters, or membrane nano-domains, due to the competition between short-range attractive and longer-range…

Soft Condensed Matter · Physics 2011-06-08 Nicolas Meilhac , Nicolas Destainville

We show that a viscoelastic thin sheet driven out of equilibrium by active structural remodelling develops a rich variety of shapes as a result of a competition between viscous relaxation and activity. In the regime where active processes…

Soft Condensed Matter · Physics 2020-02-26 D. A. Matoz-Fernandez , Fordyce A. Davidson , Nicola R. Stanley-Wall , Rastko Sknepnek

We present a simple model of adaptive radiations in evolution based on species competition. Competition is found to promote species divergence and branching, and to dampen the net species production. In the model simulations, high taxonomic…

Populations and Evolution · Quantitative Biology 2007-05-23 Birgitte Freiesleben De Blasio , Fabio Vittorio De Blasio

Confinement can have a dramatic effect on the behavior of all sorts of particulate systems and it therefore is an important phenomenon in many different areas of physics and technology. Here, we investigate the role played by the softness…

Quality-Diversity is a family of evolutionary algorithms that generate diverse, high-performing solutions through local competition principles inspired by natural evolution. While research has focused on improving specific aspects of…

Neural and Evolutionary Computing · Computer Science 2025-02-04 Ryan Bahlous-Boldi , Maxence Faldor , Luca Grillotti , Hannah Janmohamed , Lisa Coiffard , Lee Spector , Antoine Cully

A fundamental task in developmental biology is to identify the mechanisms which drive morphogenesis. In many cases, pattern formation is driven by the positional information determined by both the gradient of maternal factors and hard-wired…

Molecular Networks · Quantitative Biology 2007-05-23 L. Diambra , Luciano da Fontoura Costa

Habitat fragmentation, often driven by human activities, alters ecological landscapes by disrupting connectivity and reshaping species interactions. In such fragmented environments, habitats can be modeled as networks, where individuals…

Populations and Evolution · Quantitative Biology 2025-11-07 James Austin Orgeron , Malbor Asllani

Motivated by recent experiments on colloidal systems with competing attractive and repulsive interactions, we simulate a two-dimensional system of colloids with competing interactions that can undergo fragmentation. In the absence of any…

Soft Condensed Matter · Physics 2008-11-26 C. J. Olson Reichhardt , C. Reichhardt , A. R. Bishop

The emergence of complex organs is driven by the coordinated proliferation, migration and differentiation of precursor cells. The fate behaviour of these cells is reflected in the time evolution their progeny, termed clones, which serve as…

We use inverse methods of statistical mechanics to explore trade-offs associated with designing interactions to stabilize self-assembled structures against changes in density or temperature. Specifically, we find isotropic,convex-repulsive…

Soft Condensed Matter · Physics 2018-01-10 William D. Piñeros , Michael Baldea , Thomas M. Truskett

The adaptive immune system constantly remodels its lymphocyte repertoire for better protection against future pathogens. Its ability to improve antigen recognition on the fly relies on somatic mutation and selective expansion of B…

Biological Physics · Physics 2022-09-29 Hongda Jiang , Shenshen Wang

We perform molecular dynamics simulations for a simple coarse-grained model of crambin placed inside of a softly repulsive sphere of radius R. The confinement makes folding at the optimal temperature slower and affects the folding…

Biomolecules · Quantitative Biology 2008-12-01 M. Wojciechowski , Marek Cieplak

Resource competition is a fundamental interaction in natural communities.However little is known about competition in spatial environments where organisms are able to regulate resource distributions. Here, we analyze the competition of two…

Populations and Evolution · Quantitative Biology 2011-02-24 Alexei B. Ryabov , Bernd Blasius

Packing under confinement could generate rich ordered structures through entropic effects, which is a fundamental problem in condensed matter, biophysics and material science. The influence of confinement to the anisotropic hard…

Soft Condensed Matter · Physics 2026-05-12 Zhongtian Yuan , Yao Li