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The behaviour of materials under spatial confinement is sensitively dependent on the nature of the confining boundaries. In two dimensions, confinement within a hard circular boundary inhibits the hexagonal ordering observed in bulk systems…

Soft Condensed Matter · Physics 2015-06-17 Ian Williams , Erdal C. Oğuz , Robert L. Jack , Paul Bartlett , Hartmut Löwen , C. Patrick Royall

We demonstrate how concepts of statistical mechanics of interacting particles can have important implications in the choice of interaction potentials to model qualitative properties of cell aggregates in theoretical biology. We illustrate…

Cell Behavior · Quantitative Biology 2017-06-29 J. A. Carrillo , A. Colombi , M. Scianna

Different pathogens spreading in the same host population often generate complex co-circulation dynamics because of the many possible interactions between the pathogens and the host immune system, the host life cycle, and the space…

Populations and Evolution · Quantitative Biology 2014-12-18 Chiara Poletto , Sandro Meloni , Ashleigh Van Metre , Vittoria Colizza , Yamir Moreno , Alessandro Vespignani

We discuss a cellular automata model to study the competition between an emergent better fitted species against an existing majority species. The model implement local fights among small group of individual and a synchronous random walk on…

Disordered Systems and Neural Networks · Physics 2009-11-07 Serge Galam , Bastien Chopard , Michel Droz

The behaviour and fate of tissue cells is controlled by the rigidity and geometry of their adhesive environment, possibly through forces localized to sites of adhesion. We introduce a mechanical model that predicts cellular force…

Cell Behavior · Quantitative Biology 2009-07-24 Ilka B. Bischofs , Sebastian S. Schmidt , Ulrich S. Schwarz

Alignment interactions in active matter are typically modeled as relaxational dynamics toward local consensus. In unbounded systems, this makes alignment effectively decoupled from local density and therefore unable to sustain self-confined…

Soft Condensed Matter · Physics 2026-04-10 Julian Giraldo-Barreto , Viktor Holubec

The problem of competitive nucleation in the framework of Probabilistic Cellular Automata is studied from the dynamical point of view. The dependence of the metastability scenario on the self--interaction is discussed. An intermediate…

Statistical Mechanics · Physics 2015-05-13 Emilio N. M. Cirillo , Cristian Spitoni , Francesca R. Nardi

Biologically inspired pressure actuated cellular structures can alter their shape through pressure variations. Previous work introduced a computational framework for pressure actuated cellular structures which was limited to two cell rows…

Quantitative Methods · Quantitative Biology 2017-04-10 Markus Pagitz , Remco I. Leine

In growing populations, the fate of mutations depends on their competitive ability against the ancestor and their ability to colonize new territory. Here we present a theory that integrates both aspects of mutant fitness by coupling the…

Populations and Evolution · Quantitative Biology 2023-01-19 Daniel W. Swartz , Hyunseok Lee , Mehran Kardar , Kirill S. Korolev

Cancer results from a sequence of genetic and epigenetic changes which lead to a variety of abnormal phenotypes including increased proliferation and survival of somatic cells, and thus, to a selective advantage of pre-cancerous cells. The…

Populations and Evolution · Quantitative Biology 2011-12-05 Erik A. Martens , R. Kostadinov , Carlo C. Maley , Oskar Hallatschek

The problem of natural selection in dispersal-structured populations consisting of individuals characterized by different diffusion coefficients is studied. The competition between the organisms is taken into account through the assumption…

Adaptation and Self-Organizing Systems · Physics 2020-05-01 E. Heinsalu , D. Navidad Maeso , M. Patriarca

Despite their importance in many biological, ecological and physical processes, microorganismal fluid flows under tight confinement have not been investigated experimentally. Strong screening of Stokelets in this geometry suggests that the…

Biological Physics · Physics 2019-12-18 Raphaël Jeanneret , Dmitri O. Pushkin , Marco Polin

Cells coexist together in colonies or as tissues. Their behaviour is controlled by an interplay between intercellular forces and biochemical regulation. We develop a simple model of the cell cycle, the fundamental regulatory network…

Biological Physics · Physics 2021-08-04 Jintao Li , Simon K. Schnyder , Matthew S. Turner , Ryoichi Yamamoto

Nanoscale and microscale confinement of biopolymers naturally occurs in cells and has been recently achieved in artificial structures designed for nanotechnological applications. Here, we present an extensive theoretical investigation of…

Soft Condensed Matter · Physics 2007-06-13 Frederik Wagner , Gianluca Lattanzi , Erwin Frey

Previous research on two-dimensional extensions of Hotelling's location game has argued that spatial competition leads to maximum differentiation in one dimensions and minimum differentiation in the other dimension. We expand on existing…

General Economics · Economics 2021-03-23 Jeffrey D. Michler , Benjamin M. Gramig

The initiation of directional cell motion requires symmetry breaking that can happen both with or without external stimuli. During cell crawling, forces generated by the cytoskeleton and their transmission through mechanosensitive adhesions…

Cell Behavior · Quantitative Biology 2023-06-02 Yuzhu Chen , David Saintillan , Padmini Rangamani

Adhering cells actively probe the mechanical properties of their environment and use the resulting information to position and orient themselves. We show that a large body of experimental observations can be consistently explained from one…

Soft Condensed Matter · Physics 2009-11-10 I. B. Bischofs , U. S. Schwarz

The impact of confinement on self-assembly of particles interacting with short-range attraction and long-range repulsion (SALR) potential is studied for thermodynamic states corresponding to local ordering of clusters or layers in the bulk.…

Soft Condensed Matter · Physics 2014-11-17 Jakub Pękalski , Alina Ciach , Noé G. Almarza

Apparent competition is an indirect interaction between species that share natural resources without any mutual aggression but negatively affect each other if there is a common enemy. The negative results of the apparent competition are…

Populations and Evolution · Quantitative Biology 2022-02-16 J. Menezes , B. Moura

Volumetric brain reconstructions provide an unprecedented opportunity to gain insights into the complex connectivity patterns of neurons in an increasing number of organisms. Here, we model and quantify the complexity of the resulting…

Neurons and Cognition · Quantitative Biology 2024-05-13 Anastasiya Salova , István A. Kovács
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