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Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…

Artificial Intelligence · Computer Science 2024-08-22 Yining Hua , Hongbin Na , Zehan Li , Fenglin Liu , Xiao Fang , David Clifton , John Torous

Studying the robustness of Large Language Models (LLMs) to unsafe behaviors is an important topic of research today. Building safety classification models or guard models, which are fine-tuned models for input/output safety classification…

Computation and Language · Computer Science 2025-07-30 Sowmya Vajjala

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Large language models (LLMs) are increasingly deployed in medical contexts, raising critical concerns about safety, alignment, and susceptibility to adversarial manipulation. While prior benchmarks assess model refusal capabilities for…

Computation and Language · Computer Science 2025-05-19 Sijia Chen , Xiaomin Li , Mengxue Zhang , Eric Hanchen Jiang , Qingcheng Zeng , Chen-Hsiang Yu

Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…

Artificial Intelligence · Computer Science 2025-01-27 Arjun R. Malghan

Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

Fine-tuning a general-purpose large language model (LLM) for a specific domain or task has become a routine procedure for ordinary users. However, fine-tuning is known to remove the safety alignment features of the model, even when the…

Computation and Language · Computer Science 2025-06-23 Kathleen C. Fraser , Hillary Dawkins , Isar Nejadgholi , Svetlana Kiritchenko

Large language models are rapidly transforming social science research by enabling the automation of labor-intensive tasks like data annotation and text analysis. However, LLM outputs vary significantly depending on the implementation…

Computation and Language · Computer Science 2025-10-07 Joachim Baumann , Paul Röttger , Aleksandra Urman , Albert Wendsjö , Flor Miriam Plaza-del-Arco , Johannes B. Gruber , Dirk Hovy

Healthcare monitoring is crucial for early detection, timely intervention, and the ongoing management of health conditions, ultimately improving individuals' quality of life. Recent research shows that Large Language Models (LLMs) have…

Computation and Language · Computer Science 2024-10-01 Xin Wang , Ting Dang , Vassilis Kostakos , Hong Jia

Recently, Large Language Models (LLMs) have gained significant traction in medical domain, especially in developing a QA systems to Medical QA systems for enhancing access to healthcare in low-resourced settings. This paper compares five…

Computation and Language · Computer Science 2026-02-17 Shefayat E Shams Adib , Ahmed Alfey Sani , Ekramul Alam Esham , Ajwad Abrar , Tareque Mohmud Chowdhury

The recent success of Large Language Models (LLMs) has had a significant impact on the healthcare field, providing patients with medical advice, diagnostic information, and more. However, due to a lack of professional medical knowledge,…

Computation and Language · Computer Science 2024-06-27 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Xiang Wan , Feng Jiang , Benyou Wang

With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve…

Computation and Language · Computer Science 2024-12-10 Lei Liu , Xiaoyan Yang , Junchi Lei , Yue Shen , Jian Wang , Peng Wei , Zhixuan Chu , Zhan Qin , Kui Ren

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

Large language models (LLMs) have become ubiquitous, thus it is important to understand their risks and limitations. Smaller LLMs can be deployed where compute resources are constrained, such as edge devices, but with different propensity…

Computation and Language · Computer Science 2025-04-22 Berk Atil , Vipul Gupta , Sarkar Snigdha Sarathi Das , Rebecca J. Passonneau

Large Language Models (LLMs) have emerged as powerful candidates to inform clinical decision-making processes. While these models play an increasingly prominent role in shaping the digital landscape, two growing concerns emerge in…

Computation and Language · Computer Science 2024-04-24 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

Training mental health clinicians to conduct standardized clinical assessments is challenging due to a lack of scalable, realistic practice opportunities, which can impact data quality in clinical trials. To address this gap, we introduce a…

Human-Computer Interaction · Computer Science 2025-12-30 Veronica Bossio Botero , Vijay Yadav , Jacob Ouyang , Anzar Abbas , Michelle Worthington

Software engineers in various industrial domains are already using Large Language Models (LLMs) to accelerate the process of implementing parts of software systems. When considering its potential use for ADAS or AD systems in the automotive…

Software Engineering · Computer Science 2025-05-27 Ali Nouri , Beatriz Cabrero-Daniel , Zhennan Fei , Krishna Ronanki , Håkan Sivencrona , Christian Berger

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Clinical notes recorded during a patient's perioperative journey holds immense informational value. Advances in large language models (LLMs) offer opportunities for bridging this gap. Using 84,875 pre-operative notes and its associated…

Computation and Language · Computer Science 2025-04-03 Charles Alba , Bing Xue , Joanna Abraham , Thomas Kannampallil , Chenyang Lu
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