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This study compares the efficacy of GPT-4 and clinalytix Medical AI in predicting the clinical risk of delirium development. Findings indicate that GPT-4 exhibited significant deficiencies in identifying positive cases and struggled to…

Computation and Language · Computer Science 2024-09-17 Mohamed Rezk , Patricia Cabanillas Silva , Fried-Michael Dahlweid

When building Large Language Models (LLMs), it is paramount to bear safety in mind and protect them with guardrails. Indeed, LLMs should never generate content promoting or normalizing harmful, illegal, or unethical behavior that may…

Computation and Language · Computer Science 2024-06-25 Simone Tedeschi , Felix Friedrich , Patrick Schramowski , Kristian Kersting , Roberto Navigli , Huu Nguyen , Bo Li

Numerous medical systems powered by Large Language Models (LLMs) have achieved remarkable progress in diverse healthcare tasks. However, research on their medication safety remains limited due to the lack of real world datasets, constrained…

Artificial Intelligence · Computer Science 2025-11-07 Jiahao Zhao , Luxin Xu , Minghuan Tan , Lichao Zhang , Ahmadreza Argha , Hamid Alinejad-Rokny , Min Yang

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Background Large language models (LLMs) are increasingly deployed in medical consultations, yet their safety under realistic user pressures remains understudied. Prior assessments focused on neutral conditions, overlooking vulnerabilities…

Computation and Language · Computer Science 2026-01-16 Vahideh Zolfaghari

While large language models (LLMs) achieve near-perfect scores on medical licensing exams, these evaluations inadequately reflect the complexity and diversity of real-world clinical practice. We introduce MedHELM, an extensible evaluation…

Language model deployments in consumer-facing applications introduce numerous risks. While existing research on harms and hazards of such applications follows top-down approaches derived from regulatory frameworks and theoretical analyses,…

Computers and Society · Computer Science 2025-09-10 Pierre Le Jeune , Jiaen Liu , Luca Rossi , Matteo Dora

As large language models (LLMs) increasingly mediate emotionally sensitive conversations, especially in mental health contexts, their ability to recognize and respond to high-risk situations becomes a matter of public safety. This study…

The medical ecosystem consists of the training of new clinicians and researchers, the practice of clinical medicine, and areas of adjacent research. There are many aspects of these domains that could benefit from the application of task…

Computers and Society · Computer Science 2025-07-29 Elisha D. O. Roberson

Large Language Models (LLMs) have been suggested for use in automated vulnerability repair, but benchmarks showing they can consistently identify security-related bugs are lacking. We thus develop SecLLMHolmes, a fully automated evaluation…

Cryptography and Security · Computer Science 2024-07-25 Saad Ullah , Mingji Han , Saurabh Pujar , Hammond Pearce , Ayse Coskun , Gianluca Stringhini

The integration of large language models (LLMs) into healthcare IoT systems promises faster decisions and improved medical support. LLMs are also deployed as multi-agent teams to assist AI doctors by debating, voting, or advising on…

Cryptography and Security · Computer Science 2025-12-04 Adeela Bashir , The Anh han , Zia Ush Shamszaman

Global healthcare providers are exploring use of large language models (LLMs) to provide medical advice to the public. LLMs now achieve nearly perfect scores on medical licensing exams, but this does not necessarily translate to accurate…

Large Language Models (LLMs) demonstrate complex responses to threat-based manipulations, revealing both vulnerabilities and unexpected performance enhancement opportunities. This study presents a comprehensive analysis of 3,390…

Cryptography and Security · Computer Science 2025-07-30 Atil Samancioglu

Large language models (LLMs) are increasingly used to provide health advice, yet evidence on how their accuracy varies across languages, topics and information sources remains limited. We assess how linguistic and contextual factors affect…

General Economics · Economics 2026-02-25 Prashant Garg , Thiemo Fetzer

Large Language Models (LLMs) are increasingly used to control robotic systems such as drones, but their risks of causing physical threats and harm in real-world applications remain unexplored. Our study addresses the critical gap in…

Machine Learning · Computer Science 2026-02-20 Yung-Chen Tang , Pin-Yu Chen , Tsung-Yi Ho

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

Large Language Models (LLMs) have demonstrated potential in cybersecurity applications but have also caused lower confidence due to problems like hallucinations and a lack of truthfulness. Existing benchmarks provide general evaluations but…

This study addresses categories of harm surrounding Large Language Models (LLMs) in the field of artificial intelligence. It addresses five categories of harms addressed before, during, and after development of AI applications:…

Computers and Society · Computer Science 2026-05-26 Kevin Chen , Saleh Afroogh , Abhejay Murali , David Atkinson , Amit Dhurandhar , Junfeng Jiao