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Large Language Models (LLMs) have significantly advanced medical question-answering by leveraging extensive clinical data and medical literature. However, the rapid evolution of medical knowledge and the labor-intensive process of manually…

Computation and Language · Computer Science 2025-07-01 Mohammad Reza Rezaei , Reza Saadati Fard , Jayson L. Parker , Rahul G. Krishnan , Milad Lankarany

Large language models (LLMs), such as GPT3.5, GPT4 and LLAMA2 perform surprisingly well and outperform human experts on many tasks. However, in many domain-specific evaluations, these LLMs often suffer from hallucination problems due to…

Computation and Language · Computer Science 2024-04-19 Yuqi Wang , Boran Jiang , Yi Luo , Dawei He , Peng Cheng , Liangcai Gao

Electronic Health Records (EHR)-based disease prediction models have demonstrated significant clinical value in promoting precision medicine and enabling early intervention. However, existing large language models face two major challenges:…

Computation and Language · Computer Science 2025-06-19 Junke Wang , Hongshun Ling , Li Zhang , Longqian Zhang , Fang Wang , Yuan Gao , Zhi Li

Medical diagnosis prediction plays a critical role in disease detection and personalized healthcare. While machine learning (ML) models have been widely adopted for this task, their reliance on supervised training limits their ability to…

Artificial Intelligence · Computer Science 2025-07-08 Yuzhang Xie , Hejie Cui , Ziyang Zhang , Jiaying Lu , Kai Shu , Fadi Nahab , Xiao Hu , Carl Yang

Large language models (LLMs) typically improve performance by either retrieving semantically similar information, or enhancing reasoning abilities through structured prompts like chain-of-thought. While both strategies are considered…

Computation and Language · Computer Science 2024-10-16 Yejin Kim , Eojin Kang , Juae Kim , H. Howie Huang

Clinicians are increasingly looking towards machine learning to gain insights about patient evolutions. We propose a novel approach named Multi-Modal UMLS Graph Learning (MMUGL) for learning meaningful representations of medical concepts…

Machine Learning · Computer Science 2024-02-07 Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Predicting diseases solely from patient-side information, such as demographics and self-reported symptoms, has attracted significant research attention due to its potential to enhance patient awareness, facilitate early healthcare…

Artificial Intelligence · Computer Science 2025-12-10 Yibowen Zhao , Yinan Zhang , Zhixiang Su , Lizhen Cui , Chunyan Miao

Large language models (LLMs) have made remarkable strides in various natural language processing tasks, but their performance on complex reasoning problems remains hindered by a lack of explainability and trustworthiness. This issue, often…

Computation and Language · Computer Science 2025-10-21 Rong Wu , Pinlong Cai , Jianbiao Mei , Licheng Wen , Tao Hu , Xuemeng Yang , Daocheng Fu , Botian Shi

Recently, Knowledge Graphs (KGs) have been successfully coupled with Large Language Models (LLMs) to mitigate their hallucinations and enhance their reasoning capability, such as in KG-based retrieval-augmented frameworks. However, current…

Artificial Intelligence · Computer Science 2024-10-22 Bo Ni , Yu Wang , Lu Cheng , Erik Blasch , Tyler Derr

In this paper, we propose a novel graph neural network-based recommendation model called KGLN, which leverages Knowledge Graph (KG) information to enhance the accuracy and effectiveness of personalized recommendations. We first use a…

Information Retrieval · Computer Science 2024-02-06 Chaoyang Zhang , Yanan Li , Shen Chen , Siwei Fan , Wei Li

Knowledge Graphs (KGs), as structured knowledge bases that organize relational information across diverse domains, provide a unified semantic foundation for cross-domain recommendation (CDR). By integrating symbolic knowledge with user-item…

Information Retrieval · Computer Science 2025-11-05 Yuhan Wang , Qing Xie , Zhifeng Bao , Mengzi Tang , Lin Li , Yongjian Liu

Incorporating factual knowledge into pre-trained language models (PLM) such as BERT is an emerging trend in recent NLP studies. However, most of the existing methods combine the external knowledge integration module with a modified…

Computation and Language · Computer Science 2022-05-06 Yinquan Lu , Haonan Lu , Guirong Fu , Qun Liu

Biomedical knowledge graphs underwrite drug repurposing and clinical decision support, yet the upstream ontologies they depend on update on independent cycles that add millions of edges and deprecate hundreds of thousands more between…

Artificial Intelligence · Computer Science 2026-05-12 Yousef A. Radwan , Yao Li , Qing Qing , Ziqi Xu , Xingtong Yu , Jiaxing Huang , Renqiang Luo , Xikun Zhang

Constructing domain-specific knowledge graphs from unstructured text remains challenging due to heterogeneous entity mentions, long-tail relation distributions, and the absence of standardized schemas. We present LEC-KG, a bidirectional…

Computation and Language · Computer Science 2026-03-02 Yikai Zeng , Yingchao Piao , Changhua Pei , Jianhui Li

Large language models (LLMs) like Claude, Mistral IA, and GPT-4 excel in NLP but lack structured knowledge, leading to factual inconsistencies. We address this by integrating Knowledge Graphs (KGs) via KG-BERT to enhance grounding and…

Computation and Language · Computer Science 2025-12-12 Nour El Houda Ben Chaabene , Hamza Hammami

Multimodal electronic health record (EHR) data is useful for disease risk prediction based on medical domain knowledge. However, general medical knowledge must be adapted to specific healthcare settings and patient populations to achieve…

Artificial Intelligence · Computer Science 2025-09-29 Mbithe Nzomo , Deshendran Moodley

Retrieval-augmented generation (RAG) has improved large language models (LLMs) by using knowledge retrieval to overcome knowledge deficiencies. However, current RAG methods often fall short of ensuring the depth and completeness of…

Computation and Language · Computer Science 2025-02-11 Shengjie Ma , Chengjin Xu , Xuhui Jiang , Muzhi Li , Huaren Qu , Cehao Yang , Jiaxin Mao , Jian Guo

Knowledge Graph (KG), as a side-information, tends to be utilized to supplement the collaborative filtering (CF) based recommendation model. By mapping items with the entities in KGs, prior studies mostly extract the knowledge information…

Information Retrieval · Computer Science 2022-12-21 Yinwei Wei , Xiang Wang , Liqiang Nie , Shaoyu Li , Dingxian Wang , Tat-Seng Chua

Knowledge Graphs have been one of the fundamental methods for integrating heterogeneous data sources. Integrating heterogeneous data sources is crucial, especially in the biomedical domain, where central data-driven tasks such as drug…

Machine Learning · Computer Science 2020-12-22 Islam Akef Ebeid , Majdi Hassan , Tingyi Wanyan , Jack Roper , Abhik Seal , Ying Ding

Knowledge Graph (KG) contains entities and the relations between entities. Due to its representation ability, KG has been successfully applied to support many medical/healthcare tasks. However, in the medical domain, knowledge holds under…

Databases · Computer Science 2019-08-20 Yang Deng , Yaliang Li , Ying Shen , Nan Du , Wei Fan , Min Yang , Kai Lei