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In order for machine learning to be deployed and trusted in many applications, it is crucial to be able to reliably explain why the machine learning algorithm makes certain predictions. For example, if an algorithm classifies a given…

Machine Learning · Statistics 2018-11-07 Amirata Ghorbani , Abubakar Abid , James Zou

Predictive Process Monitoring (PPM) often uses deep learning models to predict the future behavior of ongoing processes, such as predicting process outcomes. While these models achieve high accuracy, their lack of interpretability…

Artificial Intelligence · Computer Science 2025-06-23 Soobin Chae , Suhwan Lee , Hanna Hauptmann , Hajo A. Reijers , Xixi Lu

Although Deep Neural Networks (DNNs) have great generalization and prediction capabilities, their functioning does not allow a detailed explanation of their behavior. Opaque deep learning models are increasingly used to make important…

Computer Vision and Pattern Recognition · Computer Science 2022-09-30 Adrien Bennetot , Gianni Franchi , Javier Del Ser , Raja Chatila , Natalia Diaz-Rodriguez

The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

Recent brain tumor classification methods often report high accuracy but rely on deep, over-parameterized architectures with limited interpretability, making it difficult to determine whether predictions are driven by tumor-relevant…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Rajan Das Gupta , Md Imrul Hasan Showmick , Lei Wei , Mushfiqur Rahman Abir , Shanjida Akter , Md. Yeasin Rahat , Md. Jakir Hossen

Deep learning models have achieved promising results in breast cancer classification, yet their 'black-box' nature raises interpretability concerns. This research addresses the crucial need to gain insights into the decision-making process…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Ann-Kristin Balve , Peter Hendrix

Explainable Deep Learning has gained significant attention in the field of artificial intelligence (AI), particularly in domains such as medical imaging, where accurate and interpretable machine learning models are crucial for effective…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Subhashis Suara , Aayush Jha , Pratik Sinha , Arif Ahmed Sekh

Although deep neural networks hold the state-of-the-art in several remote sensing tasks, their black-box operation hinders the understanding of their decisions, concealing any bias and other shortcomings in datasets and model performance.…

Machine Learning · Computer Science 2021-09-21 Ioannis Kakogeorgiou , Konstantinos Karantzalos

Explainability is a vital aspect of modern AI for real-world impact and usability. The main objective of this paper is to emphasise the need to understand the predictions of Computer Vision models, specifically Convolutional Neural Network…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Ravidu Suien Rammuni Silva , Jordan J. Bird

The purported "black box" nature of neural networks is a barrier to adoption in applications where interpretability is essential. Here we present DeepLIFT (Deep Learning Important FeaTures), a method for decomposing the output prediction of…

Computer Vision and Pattern Recognition · Computer Science 2019-10-15 Avanti Shrikumar , Peyton Greenside , Anshul Kundaje

There has been a significant surge of interest recently around the concept of explainable artificial intelligence (XAI), where the goal is to produce an interpretation for a decision made by a machine learning algorithm. Of particular…

Machine Learning · Computer Science 2019-10-31 Zhong Qiu Lin , Mohammad Javad Shafiee , Stanislav Bochkarev , Michael St. Jules , Xiao Yu Wang , Alexander Wong

Trustworthy interpretation of deep learning models is critical for neuroimaging applications, yet commonly used Explainable AI (XAI) methods lack rigorous validation, risking misinterpretation. We performed the first large-scale, systematic…

Machine Learning · Computer Science 2025-08-07 Nys Tjade Siegel , James H. Cole , Mohamad Habes , Stefan Haufe , Kerstin Ritter , Marc-André Schulz

Explainable Artificial Intelligence (XAI) is an emerging research topic of machine learning aimed at unboxing how AI systems' black-box choices are made. This research field inspects the measures and models involved in decision-making and…

Artificial Intelligence · Computer Science 2021-02-04 Guang Yang , Qinghao Ye , Jun Xia

The surge in black-box AI models has prompted the need to explain the internal mechanism and justify their reliability, especially in high-stakes applications, such as healthcare and autonomous driving. Due to the lack of a rigorous…

Artificial Intelligence · Computer Science 2024-03-18 Yongjie Wang , Tong Zhang , Xu Guo , Zhiqi Shen

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

Explainable AI (XAI) underwent a recent surge in research on concept extraction, focusing on extracting human-interpretable concepts from Deep Neural Networks. An important challenge facing concept extraction approaches is the difficulty of…

Machine Learning · Computer Science 2023-02-13 Dmitry Kazhdan , Botty Dimanov , Lucie Charlotte Magister , Pietro Barbiero , Mateja Jamnik , Pietro Lio

Explainable AI (XAI) is a research area whose objective is to increase trustworthiness and to enlighten the hidden mechanism of opaque machine learning techniques. This becomes increasingly important in case such models are applied to the…

Machine Learning · Computer Science 2021-04-19 Danilo Numeroso , Davide Bacciu

Explainable Artificial Intelligence (XAI) is increasingly essential as AI systems are deployed in critical fields such as healthcare and finance, offering transparency into AI-driven decisions. Two major XAI paradigms, counterfactual…

Machine Learning · Computer Science 2026-03-17 Jacob Sanderson , Hua Mao , Wai Lok Woo

Convolutional Neural Networks (CNNs) are frequently and successfully used in medical prediction tasks. They are often used in combination with transfer learning, leading to improved performance when training data for the task are scarce.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Marta Oliveira , Rick Wilming , Benedict Clark , Céline Budding , Fabian Eitel , Kerstin Ritter , Stefan Haufe

Deep learning-based AI models have been extensively applied in genomics, achieving remarkable success across diverse applications. As these models gain prominence, there exists an urgent need for interpretability methods to establish…

Genomics · Quantitative Biology 2025-05-16 Chenyu Wang , Chaoying Zuo , Zihan Su , Yuhang Xing , Lu Li , Maojun Wang , Zeyu Zhang