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The most ubiquitous form of computational aberration correction for microscopy is deconvolution. However, deconvolution relies on the assumption that the point spread function is the same across the entire field-of-view. This assumption is…

Image and Video Processing · Electrical Eng. & Systems 2025-04-30 Amit Kohli , Anastasios N. Angelopoulos , David McAllister , Esther Whang , Sixian You , Kyrollos Yanny , Federico M. Gasparoli , Bo-Jui Chang , Reto Fiolka , Laura Waller

A point-spread function describes the optics of an imaging system and can be used to correct collected images for instrumental effects. The state of the art for deconvolving images with the point-spread function is the Richardson-Lucy…

Instrumentation and Methods for Astrophysics · Physics 2024-05-07 Stefan Johann Hofmeister

We present a semi-blind, spatially-variant deconvolution technique aimed at optical microscopy that combines a local estimation step of the point spread function (PSF) and deconvolution using a spatially variant, regularized Richardson-Lucy…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Adrian Shajkofci , Michael Liebling

Deconvolution is the most commonly used image processing method to remove the blur caused by the point-spread-function (PSF) in optical imaging systems. While this method has been successful in deblurring, it suffers from several…

Image and Video Processing · Electrical Eng. & Systems 2019-10-10 Huangxuan Zhao , Ziwen Ke , Ningbo Chen , Ke Li , Lidai Wang , Xiaojing Gong , Wei Zheng , Liang Song , Zhicheng Liu , Dong Liang , Chengbo Liu

An optical imaging system forms an object image by recollecting light scattered by the object. However, intact optical information of the object delivered through the imaging system is deteriorated by imperfect optical elements and unwanted…

Optics · Physics 2017-03-28 SangYun Lee , Kyeoreh Lee , Seungwoo Shin , YongKeun Park

Microscopy is one of the most essential imaging techniques in life sciences. High-quality images are required in order to solve (potentially life-saving) biomedical research problems. Many microscopy techniques do not achieve sufficient…

Computer Vision and Pattern Recognition · Computer Science 2018-10-24 Joris Roels , Jan Aelterman , Jonas De Vylder , Hiep Luong , Yvan Saeys , Wilfried Philips

Richardson-Lucy deconvolution is widely used to restore images from degradation caused by the broadening effects of a point spread function and corruption by photon shot noise, in order to recover an underlying object. In practice, this is…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Zachary H. Hendrix , Peter T. Brown , Tim Flanagan , Douglas P. Shepherd , Ayush Saurabh , Steve Pressé

The quality of microscopy images often suffers from optical aberrations. These aberrations and their associated point spread functions have to be quantitatively estimated to restore aberrated images. The recent state-of-the-art method…

Image and Video Processing · Electrical Eng. & Systems 2022-11-22 Kira Vinogradova , Eugene W. Myers

The Richardson-Lucy method is the most popular deconvolution method in astronomy because it preserves the number of counts and the non-negativity of the original object. Regularization is, in general, obtained by an early stopping of…

Instrumentation and Methods for Astrophysics · Physics 2012-10-10 M. Prato , R. Cavicchioli , L. Zanni , P. Boccacci , M. Bertero

We investigate possibilities to speed up iterative algorithms for non-blind image deconvolution. We focus on algorithms in which convolution with the point-spread function to be deconvolved is used in each iteration, and aim at accelerating…

Computer Vision and Pattern Recognition · Computer Science 2013-04-29 Martin Welk , Martin Erler

A new method for improving the resolution of astronomical images is presented. It is based on the principle that sampled data cannot be fully deconvolved without violating the sampling theorem. Thus, the sampled image should not be…

Astrophysics · Physics 2009-10-30 P. Magain , F. Courbin , S. Sohy

Methods of three-dimensional deconvolution (3DD) or volumetric deconvolution of optical complex-valued wavefronts diffracted by 3D samples with the 3D point spread function are presented. Particularly, the quantitative correctness of the…

Optics · Physics 2022-01-11 Tatiana Latychevskaia

In this paper, an iterative method for robust deconvolution with positivity constraints is discussed. It is based on the known variational interpretation of the Richardson-Lucy iterative deconvolution as fixed-point iteration for the…

Computer Vision and Pattern Recognition · Computer Science 2017-09-22 Martin Welk

Removing the aberrations introduced by the Point Spread Function (PSF) is a fundamental aspect of astronomical image processing. The presence of noise in observed images makes deconvolution a nontrivial task that necessitates the use of…

Instrumentation and Methods for Astrophysics · Physics 2017-05-03 Samuel Farrens , Jean-Luc Starck , Fred Maurice Ngolè Mboula

We study the problem of deconvolution for light-sheet microscopy, where the data is corrupted by spatially varying blur and a combination of Poisson and Gaussian noise. The spatial variation of the point spread function (PSF) of a…

Images of near-field SAR contains spatial-variant sidelobes and clutter, subduing the image quality. Current image restoration methods are only suitable for small observation angle, due to their assumption of 2D spatial-invariant…

Signal Processing · Electrical Eng. & Systems 2022-10-06 Wensi Zhang , Xiaoling Zhang , Xu Zhan , Yuetonghui Xu , Jun Shi , Shunjun Wei

The miniaturization of optics through the use of two-dimensional metalenses has enabled novel applications in imaging. To date, single-lens imaging remains the most common configuration, in part due to the limited focusing efficiency of…

Methods of three-dimensional deconvolution with a point-spread function as frequently employed in optical microscopy to reconstruct true three-dimensional distribution of objects are extended to holographic reconstructions. Two such schemes…

Optics · Physics 2017-08-09 Tatiana Latychevskaia , Fabian Gehri , Hans-Werner Fink

We explore the impact of different telescope apertures on the image simulation and deconvolution processes within the context of a synthetic star field. Using HCIPy and Python programming, we modelled six telescope apertures namely…

Instrumentation and Methods for Astrophysics · Physics 2024-02-09 Jyotika Roychowdhury , Kevin Derby , Daewook Kim

We investigate efficient algorithmic realisations for robust deconvolution of grey-value images with known space-invariant point-spread function, with emphasis on 1D motion blur scenarios. The goal is to make deconvolution suitable as…

Computer Vision and Pattern Recognition · Computer Science 2017-09-22 Martin Welk , Patrik Raudaschl , Thomas Schwarzbauer , Martin Erler , Martin Läuter
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