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Accurately grounding regions of interest (ROIs) is critical for diagnosis and treatment planning in medical imaging. While multimodal large language models (MLLMs) combine visual perception with natural language, current medical-grounding…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Zhonghao Yan , Muxi Diao , Yuxuan Yang , Ruoyan Jing , Jiayuan Xu , Kaizhou Zhang , Lele Yang , Yanxi Liu , Kongming Liang , Zhanyu Ma

Large Language Models (LLMs) have demonstrated remarkable capabilities in challenging, knowledge-intensive reasoning tasks. However, extending LLMs to perceive and reason over a new modality (e.g., vision), often requires costly development…

Computation and Language · Computer Science 2025-11-25 James Y. Huang , Sheng Zhang , Qianchu Liu , Guanghui Qin , Tinghui Zhu , Tristan Naumann , Muhao Chen , Hoifung Poon

Automated mental health prediction using textual data has shown promising results with deep learning and large language models. However, deploying these models in high-stakes real-world settings remains challenging, as existing approaches…

Computation and Language · Computer Science 2026-05-07 Yucheng Ruan , Ling Huang , Qika Lin , Kai He , Mengling Feng

Vision--Language Models (VLMs) show significant promise for Medical Visual Question Answering (VQA), yet their deployment in clinical settings is hindered by severe vulnerability to adversarial attacks. Standard adversarial training, while…

Artificial Intelligence · Computer Science 2025-12-23 A. A. Gde Yogi Pramana , Jason Ray , Anthony Jaya , Michael Wijaya

Rare diseases affect hundreds of millions worldwide, yet diagnosis often spans years. Convectional pipelines decouple noisy evidence extraction from downstream inferential diagnosis, and general/medical large language models (LLMs) face…

Multimodal Large Language Models (MLLMs) often struggle to accurately perceive fine-grained visual details, especially when targets are tiny or visually subtle. This challenge can be addressed through semantic-visual information fusion,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Yuxiang Shen , Hailong Huang , Zhenkun Gao , Xueheng Li , Man Zhou , Chengjun Xie , Haoxuan Che , Xuanhua He , Jie Zhang

Healthcare decision-making represents one of the most challenging domains for Artificial Intelligence (AI), requiring the integration of diverse knowledge sources, complex reasoning, and various external analytical tools. Current AI systems…

Computation and Language · Computer Science 2025-06-03 Yexiao He , Ang Li , Boyi Liu , Zhewei Yao , Yuxiong He

In medical visual question answering (Med-VQA), achieving accurate responses relies on three critical steps: precise perception of medical imaging data, logical reasoning grounded in visual input and textual questions, and coherent answer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Songtao Jiang , Yuan Wang , Ruizhe Chen , Yan Zhang , Ruilin Luo , Bohan Lei , Sibo Song , Yang Feng , Jimeng Sun , Jian Wu , Zuozhu Liu

While large language models show promise in medical applications, achieving expert-level clinical reasoning remains challenging due to the need for both accurate answers and transparent reasoning processes. To address this challenge, we…

Machine Learning · Computer Science 2025-09-22 Chi Liu , Derek Li , Yan Shu , Robin Chen , Derek Duan , Teng Fang , Bryan Dai

Vision-language models have demonstrated impressive capabilities in general medical visual question answering, yet due to limited interpretability, it remains unclear whether their predictions reflect evidence-grounded clinical reasoning or…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Wen Ma , Fucheng Niu , Zhiting Fan , Zikai Xiao , Jiaxiang Liu , Zuozhu Liu

Bias in medical artificial intelligence is conventionally viewed as a defect requiring elimination. However, human reasoning inherently incorporates biases shaped by education, culture, and experience, suggesting their presence may be…

Artificial Intelligence · Computer Science 2026-03-05 Farhad Abtahi , Mehdi Astaraki , Fernando Seoane

While chain-of-thought (CoT) reasoning has substantially improved multimodal large language models (MLLMs) on complex reasoning tasks, existing approaches largely rely on long textual reasoning trajectories and provide limited mechanisms…

Artificial Intelligence · Computer Science 2026-02-10 Siqu Ou , Tianrui Wan , Zhiyuan Zhao , Junyu Gao , Xuelong Li

Large vision-language models (LVLMs) have witnessed significant progress on visual understanding tasks. However, they often prioritize language knowledge over image information on visual reasoning tasks, incurring performance degradation.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Jingqi Zhou , Sheng Wang , Jingwei Dong , Kai Liu , Lei Li , Jiahui Gao , Jiyue Jiang , Lingpeng Kong , Chuan Wu

Timely and personalized treatment decisions are essential across a wide range of healthcare settings where patient responses can vary significantly and evolve over time. Clinical data used to support these treatment decisions are often…

Machine Learning · Computer Science 2025-12-03 Qianyi Xu , Gousia Habib , Feng Wu , Dilruk Perera , Mengling Feng

Current deep learning models are mostly task specific and lack a user-friendly interface to operate. We present Meta-EyeFM, a multi-function foundation model that integrates a large language model (LLM) with vision foundation models (VFMs)…

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

The evolution of Remote Sensing Vision-Language Models(RS-VLMs) emphasizes the importance of transitioning from perception-centric recognition toward high-level deductive reasoning to enhance cognitive reliability in complex spatial tasks.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Wenshuai Li , Xiantai Xiang , Zixiao Wen , Guangyao Zhou , Ben Niu , Feng Wang , Lijia Huang , Qiantong Wang , Yuxin Hu

Large vision-language models have achieved remarkable progress in visual reasoning, yet most existing systems rely on single-step or text-only reasoning, limiting their ability to iteratively refine understanding across multiple visual…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Wenfang Sun , Hao Chen , Yingjun Du , Yefeng Zheng , Cees G. M. Snoek

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

Machine Learning · Computer Science 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe

Vision--language models (VLMs) process images as visual tokens, yet their intermediate reasoning is often carried out in text, which can be suboptimal for visually grounded radiology tasks. Radiologists instead diagnose via sequential…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Yiwei Li , Zihao Wu , Yanjun Lv , Hanqi Jiang , Weihang You , Zhengliang Liu , Dajiang Zhu , Xiang Li , Quanzheng Li , Tianming Liu , Lin Zhao