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Medical vision-language models (VLMs) excel at image-text understanding but typically rely on a single-pass reasoning that neglects localized visual cues. In clinical practice, however, human experts iteratively scan, focus, and refine the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Kaitao Chen , Shaohao Rui , Yankai Jiang , Jiamin Wu , Qihao Zheng , Chunfeng Song , Xiaosong Wang , Mu Zhou , Mianxin Liu

Medical diagnosis is not a single prediction from a fully specified vignette. It is a sequential workup: clinicians decide what evidence to obtain, revise a differential diagnosis, and stop when the diagnosis is sufficiently supported. Most…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Jiazhen Pan , Weixiang Shen , Jun Li , Julian Canisius , Felix Bitzer , Paula Roßmüller , Jiancheng Yang , Virginie Kreutzinger , Daniel Rueckert , Benedikt Wiestler

Fundus imaging such as CFP, OCT and UWF is crucial for the early detection of retinal anomalies and diseases. Fundus image understanding, due to its knowledge-intensive nature, poses a challenging vision-language task. An emerging approach…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Yuchuan Deng , Qijie Wei , Kaiheng Qian , Jiazhen Liu , Zijie Xin , Bangxiang Lan , Jingyu Liu , Jianfeng Dong , Xirong Li

Clinical diagnosis guidelines aim at specifying the steps that may lead to a diagnosis. Inspired by guidelines, we aim to learn the optimal sequence of actions to perform in order to obtain a correct diagnosis from electronic health…

Machine Learning · Computer Science 2023-11-16 Lillian Muyama , Antoine Neuraz , Adrien Coulet

Dynamic diagnosis is desirable when medical tests are costly or time-consuming. In this work, we use reinforcement learning (RL) to find a dynamic policy that selects lab test panels sequentially based on previous observations, ensuring…

Machine Learning · Computer Science 2023-03-01 Zheng Yu , Yikuan Li , Joseph Kim , Kaixuan Huang , Yuan Luo , Mengdi Wang

The rapid advancements in Vision Language Models (VLMs) have prompted the development of multi-modal medical assistant systems. Despite this progress, current models still have inherent probabilistic uncertainties, often producing erroneous…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Xiao Liang , Di Wang , Zhicheng Jiao , Ronghan Li , Pengfei Yang , Quan Wang , Tat-Seng Chua

Recent advances in Vision-Language Models (VLMs) have benefited from Reinforcement Learning (RL) for enhanced reasoning. However, existing methods still face critical limitations, including the lack of low-level visual information and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Zhiheng Wu , Tong Wang , Shuning Wang , Naiming Liu , Yumeng Zhang

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

Computation and Language · Computer Science 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

Medical Multimodal Large Language Models (MLLMs) have demonstrated remarkable capabilities across diverse healthcare tasks. However, current post-training strategies, such as supervised fine-tuning and reinforcement learning, heavily depend…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Dunyuan Xu , Xikai Yang , Juzheng Miao , Yaoqian Li , Jinpeng Li , Pheng-Ann Heng

The diagnosis of pathological images is often limited by expert availability and regional disparities, highlighting the importance of automated diagnosis using Vision-Language Models (VLMs). Traditional multimodal models typically emphasize…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Jianyu Wu , Hao Yang , Xinhua Zeng , Guibing He , Zhiyu Chen , Zihui Li , Xiaochuan Zhang , Yangyang Ma , Run Fang , Yang Liu

Cognitive diagnosis is an essential research topic in intelligent education, aimed at assessing the level of mastery of different skills by students. So far, many research works have used deep learning models to explore the complex…

Machine Learning · Computer Science 2025-12-30 Jin Wu , Chanjin Zheng

Medical Question-Answering (QA) encompasses a broad spectrum of tasks, including multiple choice questions (MCQ), open-ended text generation, and complex computational reasoning. Despite this variety, a unified framework for delivering…

Computation and Language · Computer Science 2025-06-23 Xiaotian Zhang , Yuan Wang , Zhaopeng Feng , Ruizhe Chen , Zhijie Zhou , Yan Zhang , Hongxia Xu , Jian Wu , Zuozhu Liu

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Lesion detection, symptom tracking, and visual explainability are central to real-world medical image analysis, yet current medical Vision-Language Models (VLMs) still lack mechanisms that translate their broad knowledge into clinically…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Woohyeon Park , Jaeik Kim , Sunghwan Steve Cho , Pa Hong , Wookyoung Jeong , Yoojin Nam , Namjoon Kim , Ginny Y. Wong , Ka Chun Cheung , Jaeyoung Do

Medical images often contain multiple labels with imbalanced distributions and co-occurrence, leading to bias in multi-label medical image classification. Close collaboration between medical professionals and machine learning practitioners…

Human-Computer Interaction · Computer Science 2025-07-30 Shaohan Shi , Yuheng Shao , Haoran Jiang , Yunjie Yao , Zhijun Zhang , Xu Ding , Quan Li

Large scale vision language models have shown promise in automating chest Xray interpretation, yet their clinical utility remains limited by a gap between model outputs and radiologist reasoning. Most systems optimize for semantic…

Artificial Intelligence · Computer Science 2026-04-17 Kinhei Lee , Peiyuan Jing , Zhenxuan Zhang , Yue Yang , Tao Wang , Dominic C Marshall , Yingying Fang , Guang Yang

Vision-Language Navigation requires agents to act coherently over long horizons by understanding not only local visual context but also how far they have advanced within a multi-step instruction. However, recent Vision-Language-Action…

Self-supervised learning is an efficient pre-training method for medical image analysis. However, current research is mostly confined to specific-modality data pre-training, consuming considerable time and resources without achieving…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Yiwen Ye , Yutong Xie , Jianpeng Zhang , Ziyang Chen , Qi Wu , Yong Xia

Medical dialogue systems have attracted significant attention for their potential to act as medical assistants. Enabling these medical systems to emulate clinicians' diagnostic reasoning process has been the long-standing research focus.…

Computation and Language · Computer Science 2024-06-21 Kaishuai Xu , Yi Cheng , Wenjun Hou , Qiaoyu Tan , Wenjie Li

Clinical diagnosis begins with doctor-patient interaction, during which physicians iteratively gather information, determine examination and refine differential diagnosis through patients' response. This dynamic clinical-reasoning process…

Computation and Language · Computer Science 2025-12-30 Yuqi Tang , Jing Yu , Zichang Su , Kehua Feng , Zhihui Zhu , Libin Wang , Lei Liang , Qiang Zhang , Keyan Ding , Huajun Chen
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