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This paper presents a hybrid modeling approach that couples an Agent-Based Model (ABM) with a partial differential equation (PDE) model in an epidemic setting to simulate the spatial spread of infectious diseases using a compartmental…

Multiagent Systems · Computer Science 2026-01-21 Kristina Kehrer , Tim O. F. Conrad

Developing safety policies to protect large groups of individuals working in indoor environments from disease spread is an important and challenging task. To address this issue, we investigate the scenario of workers becoming infected by a…

Computational Engineering, Finance, and Science · Computer Science 2025-01-08 Krzysztof Domino , Arkadiusz Sochan , Jarosław Adam Miszczak

Interaction-driven modeling of diseases over real-world contact data has been shown to promote the understanding of the spread of diseases in communities. This temporal modeling follows the path-preserving order and timing of the contacts,…

Applications · Statistics 2023-07-13 Yanir Marmor , Alex Abbey , Yuval Shahar , Osnat Mokryn

We incorporate local ventilation effects into a spatially dependent generalisation of the Wells--Riley model for airborne disease transmission. Aerosol production and removal through ventilation, biological deactivation, and gravitational…

Quantitative Methods · Quantitative Biology 2025-07-10 Alexander Pretty , Ian M. Griffiths , Zechariah Lau , Katerina Kaouri

Computational models of infectious disease can be broadly categorized into two types: individual-based (Agent-based), or compartmental models. While compartmental models can be structured to separate distinct sectors of a population, they…

Populations and Evolution · Quantitative Biology 2021-12-14 Cameron Zachreson , Sheryl Chang , Nathan Harding , Mikhail Prokopenko

When exposure measurement error (EME), confounder measurement error (CME), or both are present, health effect estimates regarding exposure mixtures and critical exposure time-window may not represent the true effects. For example, in air…

Statistics Theory · Mathematics 2025-05-28 Honghyok Kim

The importance of indoor human mobility in the transmission dynamics of respiratory infectious diseases has been acknowledged. Previous studies have predominantly addressed a single type of mobility behavior such as queueing and a series of…

Computers and Society · Computer Science 2023-11-30 Ziwei Cui , Ming Cai , Zheng Zhu , Gongbo Chen , Yao Xiao

Computational disease modeling plays a crucial role in understanding and controlling the transmission of infectious diseases. While agent-based models (ABMs) provide detailed insights into individual dynamics, accurately replicating human…

Modeling and simulation approaches for infectious disease dynamics have proven to be essential tools for effective control of the spread of epidemics in the population. Among these approaches, it is obvious that compartmental mathematical…

Populations and Evolution · Quantitative Biology 2024-11-08 Selain K. Kasereka

A novel predictive modeling framework for the spread of infectious diseases using high dimensional partial differential equations is developed and implemented. A scalar function representing the infected population is defined on a…

Populations and Evolution · Quantitative Biology 2020-07-06 Sashikumaar Ganesan , Deepak Subramani

Preventive measures to reduce infection are needed to combat the COVID-19 pandemic and prepare for a possible endemic phase. Current prophylactic vaccines are highly effective to prevent disease but lose their ability to reduce viral…

Airborne respiratory diseases such as SARS-CoV-2 (COVID-19) pose significant challenges for public transportation. Several recent outbreaks of SARS-CoV-2 indicate the high risk of transmission among passengers on public buses if special…

Fluid Dynamics · Physics 2021-02-03 Zhihang Zhang , Taehoon Han , Kwang Hee Yoo , Jesse Capecelatro , Andre Boehman , Kevin Maki

Agent-based models (ABMs) have emerged as distinguished tools for epidemic modeling due to their ability to capture detailed human contact patterns and can, thus, support decision-makers in times of outbreaks and epidemics. However, as a…

Physics and Society · Physics 2026-02-04 Sascha Korf , Sophia Johanna Wagner , Gerta Köster , Martin J. Kühn

Airborne diseases can be transmitted by infectious aerosols in the near field, i.e., in close proximity, or in the far field, i.e., by infectious aerosols that are well mixed within the indoor air. Is it possible to say which mode of…

Populations and Evolution · Quantitative Biology 2023-04-25 Bardia Hejazi , Oliver Schlenczek , Birte Thiede , Gholamhossein Bagheri , Eberhard Bodenschatz

This study examined a simulated confined space modelled as a hospital waiting area, where people who could have underlying conditions congregate and mix with potentially infectious individuals. It further investigated the impact of the…

Multiagent Systems · Computer Science 2021-05-24 J. A. Sarumi , E. C. Onwubiko , O. L. A. Ogunjimi

In this work we propose a novel space-dependent multiscale model for the spread of infectious diseases in a two-dimensional spatial context on realistic geographical scenarios. The model couples a system of kinetic transport equations…

Numerical Analysis · Mathematics 2020-12-21 Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi

The transport of virus-laden aerosols from a host to a susceptible person is governed by complex turbulent airflow, and physics related to breathing, coughing and sneezing, mechanical and passive ventilation, thermal buoyancy effects,…

Fluid Dynamics · Physics 2024-06-19 Zhihang Zhang , Jesse Capecelatro , Kevin Maki

The integration of empirical data in computational frameworks to model the spread of infectious diseases poses challenges that are becoming pressing with the increasing availability of high-resolution information on human mobility and…

Populations and Evolution · Quantitative Biology 2013-04-24 Anna Machens , Francesco Gesualdo , Caterina Rizzo , Alberto E Tozzi , Alain Barrat , Ciro Cattuto

The dynamics of infection spread in populations has received popular attention since the outbreak of Covid-19 and many statistical models have been developed. One of the interesting areas of research is short-time dynamics in confined,…

Physics and Society · Physics 2025-01-22 Rahul Sheshanarayana , Prateek K. Jha

Exhaled droplet and aerosol-mediated transmission of respiratory diseases, including SARS-CoV-2, is exacerbated in poorly ventilated environments where body heat-driven airflow prevails. Employing large-scale simulations, we reveal how the…

Fluid Dynamics · Physics 2023-03-24 Chao-Ben Zhao , Jian-Zhao Wu , Bo-Fu Wang , Tienchong Chang , Quan Zhou , Kai Leong Chong