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Background: Computational drug repurposing is a cost- and time-efficient approach that aims to identify new therapeutic targets or diseases (indications) of existing drugs/compounds. It is especially critical for emerging and/or orphan…
Integrated into websites, LLM-powered chatbots offer alternative means of navigation and information retrieval, leading to a shift in how users access information on the web. Yet, predominantly closed-sourced solutions limit proliferation…
Large language models (LLMs) such as ChatGPT and GPT-4 have demonstrated impressive capabilities in various generative tasks. However, their performance is often hampered by limitations in accessing and leveraging long-term memory, leading…
This paper aims to efficiently enable large language models (LLMs) to use external knowledge and goal guidance in conversational recommender system (CRS) tasks. Advanced LLMs (e.g., ChatGPT) are limited in domain-specific CRS tasks for 1)…
Evaluating conversational systems in multi-turn settings remains a fundamental challenge. Conventional pipelines typically rely on manually defined rubrics and fixed conversational context$-$a static approach that limits coverage and fails…
Recent advances in large language models (LLMs) have shown great potential to accelerate drug discovery. However, the specialized nature of biochemical data often necessitates costly domain-specific fine-tuning, posing major challenges.…
The emergence of agent-based systems represents a significant advancement in artificial intelligence, with growing applications in automated data extraction. However, chemical information extraction remains a formidable challenge due to the…
Large Language Models (LLMs) have demonstrated significant potential in medical Question Answering (QA), yet they remain prone to hallucinations and ungrounded reasoning, limiting their reliability in high-stakes clinical scenarios. While…
Dialogue-based language models mark a huge milestone in the field of artificial intelligence, by their impressive ability to interact with users, as well as a series of challenging tasks prompted by customized instructions. However, the…
While modern dialogue systems heavily rely on large language models (LLMs), their implementation often goes beyond pure LLM interaction. Developers integrate multiple LLMs, external tools, and databases. Therefore, assessment of the…
Interactive conversational recommender systems have gained significant attention for their ability to capture user preferences through natural language interactions. However, existing approaches face substantial challenges in handling…
Therapeutic decision-making in clinical medicine constitutes a high-stakes domain in which AI guidance interacts with complex interactions among patient characteristics, disease processes, and pharmacological agents. Tasks such as drug…
We present MEDCOD, a Medically-Accurate, Emotive, Diverse, and Controllable Dialog system with a unique approach to the natural language generator module. MEDCOD has been developed and evaluated specifically for the history taking task. It…
While interacting with chatbots, users may elicit multiple intents in a single dialogue utterance. Instead of training a dedicated multi-intent detection model, we propose DialogUSR, a dialogue utterance splitting and reformulation task…
Innovation in nanophotonics currently relies on human experts who synergize specialized knowledge in photonics and coding with simulation and optimization algorithms, entailing design cycles that are time-consuming, computationally…
Drug-drug interactions (DDIs) are a leading cause of preventable adverse events, often complicating treatment and increasing healthcare costs. At the same time, knowing which drugs do not interact is equally important, as such knowledge…
Perception and understanding are two pillars of computer vision. While multimodal large language models (MLLM) have demonstrated remarkable visual understanding capabilities, they arguably lack accurate perception abilities, e.g. the…
Clinical dialogue represents a complex duality requiring both the empathetic fluency of natural conversation and the rigorous precision of evidence-based medicine. While Large Language Models possess unprecedented linguistic capabilities,…
Drug repurposing has historically been an economically infeasible process for identifying novel uses for abandoned drugs. Modern machine learning has enabled the identification of complex biochemical intricacies in candidate drugs; however,…
Natural language has long enabled human cooperation, but its lossy, ambiguous, and indirect nature limits the potential of collective intelligence. While machines are not subject to these constraints, most LLM-based multi-agent systems…