Related papers: Aligning LLMs with Biomedical Knowledge using Bala…

Developing models with robust group fairness properties is paramount, particularly in ethically sensitive domains such as medical diagnosis. Recent approaches to achieving fairness in machine learning require a substantial amount of…

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Large language models (LLMs) have achieved remarkable performance on various natural language tasks. However, they are trained on static corpora and their knowledge can become outdated quickly in the fast-changing world. This motivates the…

By pretraining on trillions of tokens, an LLM gains the capability of text generation. However, to enhance its utility and reduce potential harm, SFT and alignment are applied sequentially to the pretrained model. Because SFT and alignment…

The exponential growth of biomedical texts such as biomedical literature and electronic health records (EHRs), poses a significant challenge for clinicians and researchers to access clinical information efficiently. To tackle this…

Explorations in fine-tuning Vision-Language Models (VLMs), such as Low-Rank Adaptation (LoRA) from Parameter Efficient Fine-Tuning (PEFT), have made impressive progress. However, most approaches rely on explicit weight updates, overlooking…

Biomedical literature is a rapidly expanding field of science and technology. Classification of biomedical texts is an essential part of biomedicine research, especially in the field of biology. This work proposes the fine-tuned DistilBERT,…

Length generalization, the ability to solve problems longer than those seen during training, remains a critical challenge for large language models (LLMs). Previous work modifies positional encodings (PEs) and data formats to improve length…

Motivation: A perennial challenge for biomedical researchers and clinical practitioners is to stay abreast with the rapid growth of publications and medical notes. Natural language processing (NLP) has emerged as a promising direction for…

Post-training has demonstrated its importance in enhancing the reasoning capabilities of large language models (LLMs). The primary post-training methods can be categorized into supervised fine-tuning (SFT) and reinforcement fine-tuning…

Large Language Models (LLMs) are increasingly adopted for complex scientific text generation tasks, yet they often suffer from limitations in accuracy, consistency, and hallucination control. This thesis introduces a Parameter-Efficient…

Supervised fine-tuning (SFT) is crucial for adapting Large Language Models (LLMs) to specific tasks. In this work, we demonstrate that the order of training data can lead to significant training imbalances, potentially resulting in…

Recent advances in large language models (LLMs) and biomedical foundation models (BioFMs) have achieved strong results in biological text reasoning, molecular modeling, and single-cell analysis, yet they remain siloed in disjoint embedding…

Existing LLMs-post-training techniques are broadly categorized into supervised fine-tuning (SFT) and reinforcement fine-tuning (RFT). Each paradigm presents a distinct trade-off: (1) SFT excels at mimicking demonstration data, but can lead…

Supervised fine-tuning (SFT) provides the standard approach for teaching LLMs new behaviors from offline expert demonstrations. However, standard SFT uniformly fits all samples -- including those with low likelihood under the base model --…

The rapid advancement of large language models (LLMs) in biological-medical applications has highlighted a gap between their potential and the limited scale and often low quality of available open-source annotated textual datasets. In…

Federated fine-tuning enables Large Language Models (LLMs) to adapt to downstream tasks while preserving data privacy, but its resource-intensive nature limits deployment on edge devices. In this paper, we introduce Developmental Federated…

Existing methods for fine-tuning sparse LLMs often suffer from resource-intensive requirements and high retraining costs. Additionally, many fine-tuning methods often rely on approximations or heuristic optimization strategies, which may…

Large Language Models (LLMs) are typically fine-tuned for reasoning tasks through a two-stage pipeline of Supervised Fine-Tuning (SFT) followed by Reinforcement Learning (RL), a process fraught with catastrophic forgetting and suboptimal…

When using supervised fine-tuning (SFT) to adapt large language models (LLMs) to specific domains, a significant challenge arises: should we use the entire SFT dataset for fine-tuning? Common practice often involves fine-tuning directly on…