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Multi-modal Large Language Models (MLLMs) exhibit impressive problem-solving abilities in various domains, but their visual comprehension and abstract reasoning skills remain under-evaluated. To this end, we present PolyMATH, a challenging…

Artificial Intelligence · Computer Science 2026-05-12 Himanshu Gupta , Shreyas Verma , Ujjwala Anantheswaran , Kevin Scaria , Mihir Parmar , Swaroop Mishra , Chitta Baral

The field of computational pathology has been transformed with recent advances in foundation models that encode histopathology region-of-interests (ROIs) into versatile and transferable feature representations via self-supervised learning…

The rapid advancement of large language models (LLMs) has led to a new era marked by the development of autonomous applications in real-world scenarios, which drives innovation in creating advanced web agents. Existing web agents typically…

Computation and Language · Computer Science 2024-06-10 Hongliang He , Wenlin Yao , Kaixin Ma , Wenhao Yu , Yong Dai , Hongming Zhang , Zhenzhong Lan , Dong Yu

Rapid advancements in imaging techniques and analytical methods over the past decade have revolutionized our ability to comprehensively probe the biological world at multiple scales, pinpointing the type, quantity, location, and even…

Artificial Intelligence · Computer Science 2025-10-02 Shanghang Zhang , Gaole Dai , Tiejun Huang , Jianxu Chen

Web-scale visual entity recognition, the task of associating images with their corresponding entities within vast knowledge bases like Wikipedia, presents significant challenges due to the lack of clean, large-scale training data. In this…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Mathilde Caron , Alireza Fathi , Cordelia Schmid , Ahmet Iscen

Large Multimodal Models (LMMs) have achieved strong performance across a range of vision and language tasks. However, their spatial reasoning capabilities are under-investigated. In this paper, we construct a novel VQA dataset, Spatial-MM,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Fatemeh Shiri , Xiao-Yu Guo , Mona Golestan Far , Xin Yu , Gholamreza Haffari , Yuan-Fang Li

Multiple Instance Learning (MIL) methods have succeeded remarkably in histopathology whole slide image (WSI) analysis. However, most MIL models only offer attention-based explanations that do not faithfully capture the model's decision…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Susu Sun , Dominique van Midden , Geert Litjens , Christian F. Baumgartner

Artwork analysis is important and fundamental skill for art appreciation, which could enrich personal aesthetic sensibility and facilitate the critical thinking ability. Understanding artworks is challenging due to its subjective nature,…

Computation and Language · Computer Science 2024-08-02 Yi Bin , Wenhao Shi , Yujuan Ding , Zhiqiang Hu , Zheng Wang , Yang Yang , See-Kiong Ng , Heng Tao Shen

Whole Slide Imaging (WSI) is a cornerstone of digital pathology, offering detailed insights critical for diagnosis and research. Yet, the gigapixel size of WSIs imposes significant computational challenges, limiting their practical utility.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-15 Ravi Kant Gupta , Shounak Das , Amit Sethi

Large Language Models (LLMs) and Large Multimodal Models (LMMs) exhibit impressive problem-solving skills in many tasks and domains, but their ability in mathematical reasoning in visual contexts has not been systematically studied. To…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Pan Lu , Hritik Bansal , Tony Xia , Jiacheng Liu , Chunyuan Li , Hannaneh Hajishirzi , Hao Cheng , Kai-Wei Chang , Michel Galley , Jianfeng Gao

Multimodal large language models (MLLMs), such as GPT-4o, Gemini, LLaVA, and Flamingo, have made significant progress in integrating visual and textual modalities, excelling in tasks like visual question answering (VQA), image captioning,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Junxiao Xue , Quan Deng , Fei Yu , Yanhao Wang , Jun Wang , Yuehua Li

In Recent Years, Digital Technologies Have Made Significant Strides In Augmenting-Human-Health, Cognition, And Perception, Particularly Within The Field Of Computational-Pathology. This Paper Presents A Novel Approach To Enhancing The…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Xiaoqian Hu

Multimodal large language models (LLMs) are increasingly used to generate dermatology diagnostic narratives directly from images. However, reliable evaluation remains the primary bottleneck for responsible clinical deployment. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Yuhao Shen , Jiahe Qian , Shuping Zhang , Zhangtianyi Chen , Tao Lu , Juexiao Zhou

AI-assisted gait analysis holds promise for improving Parkinson's Disease (PD) care, but current clinical dashboards lack transparency and offer no meaningful way for clinicians to interrogate or contest AI decisions. To address this issue,…

Human-Computer Interaction · Computer Science 2025-12-11 Loc Phuc Truong Nguyen , Hung Thanh Do , Hung Truong Thanh Nguyen , Hung Cao

We explore Multimodal Large Language Models (MLLMs), which integrate LLMs like GPT-4 to handle multimodal data, including text, images, audio, and more. MLLMs demonstrate capabilities such as generating image captions and answering…

Computation and Language · Computer Science 2025-01-09 Shezheng Song , Xiaopeng Li , Shasha Li , Shan Zhao , Jie Yu , Jun Ma , Xiaoguang Mao , Weimin Zhang

The histopathology analysis is of great significance for the diagnosis and prognosis of cancers, however, it has great challenges due to the enormous heterogeneity of gigapixel whole slide images (WSIs) and the intricate representation of…

Image and Video Processing · Electrical Eng. & Systems 2024-02-09 Mingxin Liu , Yunzan Liu , Pengbo Xu , Jiquan Ma

Retrieving visual and textual information from medical literature and hospital records can enhance diagnostic accuracy for clinical image interpretation. However, multimodal retrieval-augmented diagnosis is highly challenging. We explore a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nir Mazor , Tom Hope

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi

Large vision-language models (LVLMs) have demonstrated remarkable achievements, yet the generation of non-factual responses remains prevalent in fact-seeking question answering (QA). Current multimodal fact-seeking benchmarks primarily…

Computation and Language · Computer Science 2025-03-11 Yanling Wang , Yihan Zhao , Xiaodong Chen , Shasha Guo , Lixin Liu , Haoyang Li , Yong Xiao , Jing Zhang , Qi Li , Ke Xu

Although Vision Language Models (VLMs) have shown strong generalization in medical imaging, pathology presents unique challenges due to ultra-high resolution, complex tissue structures, and nuanced clinical semantics. These factors make…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Wenchuan Zhang , Jingru Guo , Hengzhe Zhang , Penghao Zhang , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu