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Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…
Large multimodal models (LMMs) have demonstrated significant potential as generalists in vision-language (VL) tasks. However, adoption of LMMs in real-world tasks is hindered by their poor performance in tasks that require a combination of…
Deep learning based automated pathological diagnosis has markedly improved diagnostic efficiency and reduced variability between observers, yet its clinical adoption remains limited by opaque model decisions and a lack of traceable…
Multimodal large language models (MLLMs) have demonstrated strong capabilities in visual understanding, yet they remain limited in complex, multi-step reasoning that requires deep searching and integrating visual evidence with external…
Vision-threatening eye diseases pose a major global health burden, with timely diagnosis limited by workforce shortages and restricted access to specialized care. While multimodal large language models (MLLMs) show promise for medical image…
Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…
Recent advances in Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities. However, evaluating their capacity for human-like understanding in One-Image Guides remains insufficiently explored. One-Image Guides are…
In emergency departments, rural hospitals, or clinics in less developed regions, clinicians often lack fast image analysis by trained radiologists, which can have a detrimental effect on patients' healthcare. Large Language Models (LLMs)…
Multimodal large language models (MLLMs) represent an evolutionary expansion in the capabilities of traditional large language models, enabling them to tackle challenges that surpass the scope of purely text-based applications. It leverages…
The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods. In this paper, we propose MDNet to establish a direct multimodal…
Multimodal large language models (MLLMs) are designed to process and integrate information from multiple sources, such as text, speech, images, and videos. Despite its success in language understanding, it is critical to evaluate the…
The emergence of Multimodal Large Language Models (MLLMs) has revolutionized image understanding by bridging textual and visual modalities. However, these models often struggle with capturing fine-grained semantic information, such as the…
The deep neural network is a research hotspot for histopathological image analysis, which can improve the efficiency and accuracy of diagnosis for pathologists or be used for disease screening. The whole slide pathological image can reach…
Large-scale Artificial General Intelligence (AGI) models, including Large Language Models (LLMs) such as ChatGPT/GPT-4, have achieved unprecedented success in a variety of general domain tasks. Yet, when applied directly to specialized…
Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…
Frontier large language models (LLMs), such as GPT-5, Claude 4.5, Gemini 3, Llama 4, and DeepSeek-R1, represent a transformative class of AI tools capable of revolutionizing various aspects of healthcare by generating human-like responses…
Multimodal Large Language Models (MLLMs) promise advanced vision language capabilities, yet their effectiveness in visually presented mathematics remains underexplored. This paper analyzes the development and evaluation of MLLMs for…
Combining Large Language Models (LLMs) with external specialized tools (LLMs+tools) is a recent paradigm to solve multimodal tasks such as Visual Question Answering (VQA). While this approach was demonstrated to work well when optimized and…
Deep convolutional neural networks (CNNs) are the current state-of-the-art for digital analysis of histopathological images. The large size of whole-slide microscopy images (WSIs) requires advanced memory handling to read, display and…
Recent work has shown promising performance of frontier large language models (LLMs) and their multimodal counterparts in medical quizzes and diagnostic tasks, highlighting their potential for broad clinical utility given their accessible,…