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Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…
Photovoltaic cells are electronic devices that convert light energy to electricity, forming the backbone of solar energy harvesting systems. An essential step in the manufacturing process for photovoltaic cells is visual quality inspection…
Deep neural networks currently deliver promising results for microscopy image cell segmentation, but they require large-scale labelled databases, which is a costly and time-consuming process. In this work, we relax the labelling requirement…
Light sheet fluorescence microscopy (LSM) enables high-resolution, three-dimensional (3D) imaging of biological specimens, providing rich volumetric data for studying cellular organization, pathology, and vascular networks. However, the…
Microscopy images contain rich information about how cells respond to perturbations, making them essential to applications like drug screening. To quantify images, researchers often use representation extraction methods, and recent years…
There has been a lot of recent research on improving the efficiency of fine-tuning foundation models. In this paper, we propose a novel efficient fine-tuning method that allows the input image size of Segment Anything Model (SAM) to be…
It is clinically crucial and potentially very beneficial to be able to analyze and model directly the spatial distributions of cells in histopathology whole slide images (WSI). However, most existing WSI datasets lack cell-level…
Fluorescence microscopy has enabled a dramatic development in modern biology by visualizing biological organisms with micrometer scale resolution. However, due to the diffraction limit, sub-micron/nanometer features are difficult to…
Each woman living in the United States has about 1 in 8 chance of developing invasive breast cancer. The mitotic cell count is one of the most common tests to assess the aggressiveness or grade of breast cancer. In this prognosis,…
Automated image processing approaches are indispensable for many biomedical experiments and help to cope with the increasing amount of microscopy image data in a fast and reproducible way. Especially state-of-the-art deep learning-based…
Semantic segmentation is a crucial task in biomedical image processing, which recent breakthroughs in deep learning have allowed to improve. However, deep learning methods in general are not yet widely used in practice since they require…
Deep learning classifiers for characterization of whole slide tissue morphology require large volumes of annotated data to learn variations across different tissue and cancer types. As is well known, manual generation of digital pathology…
Over the past few years, we have witnessed the success of deep learning in image recognition thanks to the availability of large-scale human-annotated datasets such as PASCAL VOC, ImageNet, and COCO. Although these datasets have covered a…
Extracting single-cell information from microscopy data requires accurate instance-wise segmentations. Obtaining pixel-wise segmentations from microscopy imagery remains a challenging task, especially with the added complexity of…
The electron microscope (EM) remains the predominant technique for elucidating intricate details of the animal nervous system at the nanometer scale. However, accurately reconstructing the complex morphology of axons and myelin sheaths…
The time-consuming task of manual segmentation challenges routine systematic quantification of disease burden. Convolutional neural networks (CNNs) hold significant promise to reliably identify locations and boundaries of tumors from PET…
Cell detection in histopathology images is of great value in clinical practice. \textit{Convolutional neural networks} (CNNs) have been applied to cell detection to improve the detection accuracy, where cell annotations are required for…
The existing crowd counting models require extensive training data, which is time-consuming to annotate. To tackle this issue, we propose a simple yet effective crowd counting method by utilizing the Segment-Everything-Everywhere Model…
The success of large language models has inspired the computer vision community to explore image segmentation foundation model that is able to zero/few-shot generalize through prompt engineering. Segment-Anything(SAM), among others, is the…
Purpose: Recent developments in computational pathology have been driven by advances in Vision Foundation Models, particularly the Segment Anything Model (SAM). This model facilitates nuclei segmentation through two primary methods:…