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Inferring adverse events (AEs) of medical products from Spontaneous Reporting Systems (SRS) databases is a core challenge in contemporary pharmacovigilance. Bayesian methods for pharmacovigilance are attractive for their rigorous ability to…

Methodology · Statistics 2025-02-17 Yihao Tan , Marianthi Markatou , Saptarshi Chakraborty

Predicting drug side-effects before they occur is a key task in keeping the number of drug-related hospitalizations low and to improve drug discovery processes. Automatic predictors of side-effects generally are not able to process the…

Machine Learning · Statistics 2022-12-01 Pietro Bongini , Elisa Messori , Niccolò Pancino , Monica Bianchini

Robots and autonomous systems require an understanding of complex events (CEs) from sensor data to interact with their environments and humans effectively. Traditional end-to-end neural architectures, despite processing sensor data…

Artificial Intelligence · Computer Science 2024-03-05 Liying Han , Mani B. Srivastava

Artificial intelligence (AI) tools for radiology are commonly unmonitored once deployed. The lack of real-time case-by-case assessments of AI prediction confidence requires users to independently distinguish between trustworthy and…

Machine learning based malware detectors become obsolete over time due to concept drift in benign and malware applications. Recent methods rely on fully labeled data and use hierarchical contrastive loss (HCL) with active learning to…

Existing approaches for predictive process monitoring are sub-symbolic, meaning that they learn correlations between descriptive features and a target feature fully based on data, e.g., predicting the surgical needs of a patient based on…

Artificial Intelligence · Computer Science 2026-04-01 Fabrizio De Santis , Gyunam Park , Wil M. P. van der Aalst , Francesco Zanichelli

Emergency management urgently requires comprehensive knowledge while having a high possibility to go beyond individuals' cognitive scope. Therefore, artificial intelligence(AI) supported decision-making under that circumstance is of vital…

Computation and Language · Computer Science 2023-11-16 Minze Chen , Zhenxiang Tao , Weitong Tang , Tingxin Qin , Rui Yang , Chunli Zhu

Event detection is a critical task for timely decision-making in graph analytics applications. Despite the recent progress towards deep learning on graphs, event detection on dynamic graphs presents particular challenges to existing…

Machine Learning · Computer Science 2023-02-15 Mert Kosan , Arlei Silva , Sourav Medya , Brian Uzzi , Ambuj Singh

Electronic health records (EHRs) form an invaluable resource for training clinical decision support systems. To leverage the potential of such systems in high-risk applications, we need large, structured tabular datasets on which we can…

Artificial Intelligence · Computer Science 2025-11-24 Paloma Rabaey , Adrick Tench , Stefan Heytens , Thomas Demeester

The analysis of adverse events (AEs) is a key component in the assessment of a drug's safety profile. Inappropriate analysis methods may result in misleading conclusions about a therapy's safety and consequently its benefit-risk ratio. The…

Electroencephalography (EEG) during sleep is used by clinicians to evaluate various neurological disorders. In sleep medicine, it is relevant to detect macro-events (> 10s) such as sleep stages, and micro-events (<2s) such as spindles and…

Signal Processing · Electrical Eng. & Systems 2018-07-17 Stanislas Chambon , Valentin Thorey , Pierrick J. Arnal , Emmanuel Mignot , Alexandre Gramfort

Emotion recognition has significant potential in healthcare and affect-sensitive systems such as brain-computer interfaces (BCIs). However, challenges such as the high cost of labeled data and variability in electroencephalogram (EEG)…

Signal Processing · Electrical Eng. & Systems 2024-11-21 Md Niaz Imtiaz , Naimul Khan

We present an operational component of a real-world patient triage system. Given a specific patient presentation, the system is able to assess the level of medical urgency and issue the most appropriate recommendation in terms of best point…

Computation and Language · Computer Science 2018-10-01 Ivan Girardi , Pengfei Ji , An-phi Nguyen , Nora Hollenstein , Adam Ivankay , Lorenz Kuhn , Chiara Marchiori , Ce Zhang

In clinical practice, physicians refrain from making decisions when patient information is insufficient. This behavior, known as abstention, is a critical safety mechanism preventing potentially harmful misdiagnoses. Recent investigations…

Computation and Language · Computer Science 2025-09-30 Xilin Dang , Kexin Chen , Xiaorui Su , Ayush Noori , Iñaki Arango , Lucas Vittor , Xinyi Long , Yuyang Du , Marinka Zitnik , Pheng Ann Heng

Understanding the factors that trigger or prevent undesirable health outcomes across patient subpopulations is essential for designing targeted interventions. While randomized controlled trials and expert-led patient interviews are standard…

Artificial Intelligence · Computer Science 2026-05-28 Shishir Adhikari , Guido Muscioni , Mark Shapiro , Plamen Petrov , Elena Zheleva

This paper proposes a novel neuro-symbolic approach for sensor signal-based knowledge discovery, focusing on identifying latent subclasses in time series classification tasks. The approach leverages gradient-based saliency maps derived from…

Artificial Intelligence · Computer Science 2025-11-11 Tim Bohne , Anne-Kathrin Patricia Windler , Martin Atzmueller

Social media can be an important source of information facilitating the detection of new safety signals in pharmacovigilance. Various approaches have investigated the analysis of social media data using AI such as NLP techniques for…

Computation and Language · Computer Science 2022-03-08 Valentin Roche , Jean-Philippe Robert , Hanan Salam

Computer-aided diagnosis systems must make critical decisions from medical images that are often noisy, ambiguous, or conflicting, yet today's models are trained on overly simplistic labels that ignore diagnostic uncertainty. One-hot labels…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Ang Nan Gu , Michael Tsang , Hooman Vaseli , Purang Abolmaesumi , Teresa Tsang

Explainability poses a major challenge to artificial intelligence (AI) techniques. Current studies on explainable AI (XAI) lack the efficiency of extracting global knowledge about the learning task, thus suffer deficiencies such as…

Computer Vision and Pattern Recognition · Computer Science 2023-06-14 Ruitao Xie , Jingbang Chen , Limai Jiang , Rui Xiao , Yi Pan , Yunpeng Cai

Electroencephalogram (EEG) signals are effective tools towards seizure analysis where one of the most important challenges is accurate detection of seizure events and brain regions in which seizure happens or initiates. However, all…

Machine Learning · Computer Science 2023-01-18 Thi Kieu Khanh Ho , Narges Armanfard