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Understanding the sequence of cognitive operations that underlie decision-making is a fundamental challenge in cognitive neuroscience. Traditional approaches often rely on group-level statistics, which obscure trial-by-trial variations in…

Neurons and Cognition · Quantitative Biology 2025-04-15 Rick den Otter , Gabriel Weindel , Sjoerd Stuit , Leendert van Maanen

When Deep Neural Networks (DNNs) are used in safety-critical systems, engineers should determine the safety risks associated with failures (i.e., erroneous outputs) observed during testing. For DNNs processing images, engineers visually…

Software Engineering · Computer Science 2022-11-09 Hazem Fahmy , Fabrizio Pastore , Lionel Briand , Thomas Stifter

The availability of a large amount of electronic health records (EHR) provides huge opportunities to improve health care service by mining these data. One important application is clinical endpoint prediction, which aims to predict whether…

Artificial Intelligence · Computer Science 2018-11-20 Luchen Liu , Jianhao Shen , Ming Zhang , Zichang Wang , Jian Tang

Retrieval-augmented generation (RAG) is a well-suited technique for retrieving privacy-sensitive Electronic Health Records (EHR). It can serve as a key module of the healthcare copilot, helping reduce misdiagnosis for healthcare…

Computation and Language · Computer Science 2025-06-30 Xuejiao Zhao , Siyan Liu , Su-Yin Yang , Chunyan Miao

Adverse Drug Reaction (ADR) is a significant public health concern world-wide. Numerous graph-based methods have been applied to biomedical graphs for predicting ADRs in pre-marketing phases. ADR detection in post-market surveillance is no…

Machine Learning · Computer Science 2020-04-02 Heeyoung Kwak , Minwoo Lee , Seunghyun Yoon , Jooyoung Chang , Sangmin Park , Kyomin Jung

Medical diagnosis requires the effective synthesis of visual manifestations and clinical metadata. However, existing methods often treat metadata as isolated tags, failing to exploit the rich semantic knowledge embedded in clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Yiqing Wang , Chunming He , Ming-Chen Lu , Mercy Pawar , Leslie Niziol , Maria Woodward , Sina Farsiu

Pharmacovigilance and clinical decision support systems utilize structured drug safety data to guide medical practice. However, existing datasets frequently depend on terminologies such as MedDRA, which limits their semantic reasoning…

Information Retrieval · Computer Science 2026-02-24 Mohammad Ashhad , Olga Mashkova , Ricardo Henao , Robert Hoehndorf

We investigate the application of the factor graph framework for blind joint channel estimation and symbol detection on time-variant linear inter-symbol interference channels. In particular, we consider the expectation maximization (EM)…

Information Theory · Computer Science 2025-02-04 Luca Schmid , Tomer Raviv , Nir Shlezinger , Laurent Schmalen

Advanced Persistent Threats (APTs) are sophisticated, long-term cyberattacks that are difficult to detect because they operate stealthily and often blend into normal system behavior. This paper presents a neuro-symbolic anomaly detection…

Machine Learning · Computer Science 2026-02-17 Asif Tauhid , Sidahmed Benabderrahmane , Mohamad Altrabulsi , Ahamed Foisal , Talal Rahwan

Despite impressive advancements in Autonomous Driving Systems (ADS), navigation in complex road conditions remains a challenging problem. There is considerable evidence that evaluating the subjective risk level of various decisions can…

Computer Vision and Pattern Recognition · Computer Science 2020-09-15 Shih-Yuan Yu , Arnav V. Malawade , Deepan Muthirayan , Pramod P. Khargonekar , Mohammad A. Al Faruque

We develop a hybrid model-based data-driven seizure detection algorithm called Mutual Information-based CNNAided Learned factor graphs (MICAL) for detection of eclectic seizures from EEG signals. Our proposed method contains three main…

Signal Processing · Electrical Eng. & Systems 2023-01-17 Bahareh Salafian , Eyal Fishel Ben-Knaan , Nir Shlezinger , Sandrine de Ribaupierre , Nariman Farsad

Objectives: With accurate estimates of expected safety results, clinical trials could be better designed and monitored. We evaluated methods for predicting serious adverse event (SAE) results in clinical trials using information only from…

Computation and Language · Computer Science 2025-08-12 Qixuan Hu , Xumou Zhang , Jinman Kim , Florence Bourgeois , Adam G. Dunn

In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent…

Quantitative Methods · Quantitative Biology 2024-07-30 Yufeng Li , Wenchao Zhao , Bo Dang , Xu Yan , Weimin Wang , Min Gao , Mingxuan Xiao

Knowledge Graph (KG) contains entities and the relations between entities. Due to its representation ability, KG has been successfully applied to support many medical/healthcare tasks. However, in the medical domain, knowledge holds under…

Databases · Computer Science 2019-08-20 Yang Deng , Yaliang Li , Ying Shen , Nan Du , Wei Fan , Min Yang , Kai Lei

Even when the causal graph underlying our data is unknown, we can use observational data to narrow down the possible values that an average treatment effect (ATE) can take by (1) identifying the graph up to a Markov equivalence class; and…

Machine Learning · Computer Science 2024-04-11 Shantanu Gupta , David Childers , Zachary C. Lipton

Deep Learning (DL) methods have been used for electrocardiogram (ECG) processing in a wide variety of tasks, demonstrating good performance compared with traditional signal processing algorithms. These methods offer an efficient framework…

Signal Processing · Electrical Eng. & Systems 2024-07-31 Adrian Atienza , Jakob Bardram , Sadasivan Puthusserypady

Preventable adverse events as a result of medical errors present a growing concern in the healthcare system. As drug-drug interactions (DDIs) may lead to preventable adverse events, being able to extract DDIs from drug labels into a…

Computation and Language · Computer Science 2019-11-06 Tung Tran , Ramakanth Kavuluru , Halil Kilicoglu

Adverse drug events (ADEs) are a serious health problem that can be life-threatening. While a lot of studies have been performed on detect correlation between a drug and an AE, limited studies have been conducted on personalized ADE risk…

Machine Learning · Computer Science 2021-04-20 Jinhe Shi , Xiangyu Gao , Chenyu Ha , Yage Wang , Guodong Gao , Yi Chen

Many diagnostic errors occur because clinicians cannot easily access relevant information in patient Electronic Health Records (EHRs). In this work we propose a method to use LLMs to identify pieces of evidence in patient EHR data that…

Biomedical events describe complex interactions between various biomedical entities. Event trigger is a word or a phrase which typically signifies the occurrence of an event. Event trigger identification is an important first step in all…

Computation and Language · Computer Science 2017-05-29 Patchigolla V S S Rahul , Sunil Kumar Sahu , Ashish Anand