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Recommendation systems in AI-based medical diagnostics and treatment constitute a critical component of AI in healthcare. Although some studies have explored this area and made notable progress, healthcare recommendation systems remain in…

Information Retrieval · Computer Science 2025-05-13 Jianan Li , Yangtao Zhou , Zhifu Zhao , Qinglan Huang , Jian Qi , Xiao He , Hua Chu , Fu Li

Spatial transcriptomics (ST) measures mRNA expression while preserving spatial organization, but multi-slice analysis faces two coupled difficulties: large non-rigid deformations across slices and inter-slice batch effects when alignment…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Bonian Han , Cong Qi , Przemyslaw Musialski , Zhi Wei

Inferring spatially resolved gene expression from histology images offers a cost-effective complement to spatial transcriptomics (ST). However, existing methods reduce this task to a simple morphology-to-expression mapping, where visual…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Junchao Zhu , Ruining Deng , Junlin Guo , Tianyuan Yao , Chongyu Qu , Juming Xiong , Zhengyi Lu , Yanfan Zhu , Marilyn Lionts , Yuechen Yang , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Spatial transcriptomics (ST) technologies have revolutionized the study of gene expression patterns in tissues by providing multimodality data in transcriptomic, spatial, and morphological, offering opportunities for understanding tissue…

Computational Engineering, Finance, and Science · Computer Science 2024-01-17 Zelin Zang , Liangyu Li , Yongjie Xu , Chenrui Duan , Kai Wang , Yang You , Yi Sun , Stan Z. Li

Spatial transcriptomics (ST) has revolutionized biomedical research by enabling high resolution gene expression profiling within tissues. However, the high cost and scarcity of high resolution ST data remain significant challenges. We…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou

The automated analysis of phonocardiograms is vital for the early diagnosis of cardiovascular disease, yet supervised deep learning is often constrained by the scarcity of expert-annotated data. In this paper, we propose the Self-Supervised…

One of the important research topics in image generative models is to disentangle the spatial contents and styles for their separate control. Although StyleGAN can generate content feature vectors from random noises, the resulting spatial…

Computer Vision and Pattern Recognition · Computer Science 2021-07-26 Gihyun Kwon , Jong Chul Ye

Different types of staining highlight different structures in organs, thereby assisting in diagnosis. However, due to the impossibility of repeated staining, we cannot obtain different types of stained slides of the same tissue area.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Zexin Li , Yiyang Lin , Zijie Fang , Shuyan Li , Xiu Li

Computer Vision has proven to be a powerful tool for analyzing Spatial Transcriptomics (ST) data. However, current models that predict spatially resolved gene expression from histopathology images suffer from significant limitations due to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Paula Cárdenas , Leonardo Manrique , Daniela Vega , Daniela Ruiz , Pablo Arbeláez

Spatial transcriptomics (ST) has revolutionised transcriptomics analysis by preserving tissue architecture, allowing researchers to study gene expression in its native spatial context. However, despite its potential, ST still faces…

Quantitative Methods · Quantitative Biology 2025-05-19 Anthony Baptista , Rosamond Nuamah , Ciro Chiappini , Anita Grigoriadis

Heterogeneous domain adaptation (HDA) transfers knowledge across source and target domains that present heterogeneities e.g., distinct domain distributions and difference in feature type or dimension. Most previous HDA methods tackle this…

Computer Vision and Pattern Recognition · Computer Science 2021-05-06 Shuang Li , Binhui Xie , Jiashu Wu , Ying Zhao , Chi Harold Liu , Zhengming Ding

Among various region embedding methods, graph-based region relation learning models stand out, owing to their strong structure representation ability for encoding spatial correlations with graph neural networks. Despite their effectiveness,…

Machine Learning · Computer Science 2023-05-09 Qianru Zhang , Chao Huang , Lianghao Xia , Zheng Wang , Zhonghang Li , Siuming Yiu

Understanding human visual attention is key to preserving cultural heritage We introduce SPGen a novel deep learning model to predict scanpaths the sequence of eye movementswhen viewers observe paintings. Our architecture uses a Fully…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Mohamed Amine Kerkouri , Marouane Tliba , Aladine Chetouani , Alessandro Bruno

Background: Spatial transcriptomics have emerged as a powerful tool in biomedical research because of its ability to capture both the spatial contexts and abundance of the complete RNA transcript profile in organs of interest. However,…

Genomics · Quantitative Biology 2025-04-18 Shuo Shuo Liu , Shikun Wang , Yuxuan Chen , Anil K. Rustgi , Ming Yuan , Jianhua Hu

Accurate and reliable lane detection is vital for the safe performance of lane-keeping assistance and lane departure warning systems. However, under certain challenging circumstances, it is difficult to get satisfactory performance in…

Computer Vision and Pattern Recognition · Computer Science 2022-07-21 Yongqi Dong , Sandeep Patil , Bart van Arem , Haneen Farah

Spatial transcriptomic (ST) clustering employs spatial and transcription information to group spots spatially coherent and transcriptionally similar together into the same spatial domain. Graph convolution network (GCN) and graph attention…

Quantitative Methods · Quantitative Biology 2023-10-24 Chen Zhang , Junhui Gao , Lingxin Kong , Guangshuo cao , Xiangyu Guo , Wei Liu

Knowledge distillation (KD) is a valuable yet challenging approach that enhances a compact student network by learning from a high-performance but cumbersome teacher model. However, previous KD methods for image restoration overlook the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Yunshuai Zhou , Junbo Qiao , Jincheng Liao , Wei Li , Simiao Li , Jiao Xie , Yunhang Shen , Jie Hu , Shaohui Lin

Stain variations often decrease the generalization ability of deep learning based approaches in digital histopathology analysis. Two separate proposals, namely stain normalization (SN) and stain augmentation (SA), have been spotlighted to…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Yiqing Shen , Yulin Luo , Dinggang Shen , Jing Ke

Accurate sleep stage classification across datasets remains challenging due to variability in EEG channel montages, sampling rates, recording environments, and subject populations. Although deep learning has shown considerable promise for…

Machine Learning · Computer Science 2026-05-11 Unaza Tallal , Shruti Kshirsagar , Ankita Shukla

X-ray Photoelectron Spectroscopy (XPS) is a crucial technique for material surface analysis, yet interpreting its spectra is often challenging for both human analysts and automated methods due to the prevalence of variable spectral shifts…

Materials Science · Physics 2026-03-06 Issa Saddiq , Yuxin Fan , Robert G. Palgrave , Mark A. Isaacs , David Morgan , Keith T. Butler
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