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Endovascular procedures have revolutionized vascular disease treatment, yet their manual execution is challenged by the demands for high precision, operator fatigue, and radiation exposure. Robotic systems have emerged as transformative…

Providing high quality explanations for AI predictions based on machine learning is a challenging and complex task. To work well it requires, among other factors: selecting a proper level of generality/specificity of the explanation;…

Recent advances in computational pathology have led to the emergence of numerous foundation models. These models typically rely on general-purpose encoders with multi-instance learning for whole slide image (WSI) classification or apply…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Yuxuan Sun , Yixuan Si , Chenglu Zhu , Kai Zhang , Zhongyi Shui , Bowen Ding , Tao Lin , Lin Yang

Multimodal reasoning remains a fundamental challenge in artificial intelligence. Despite substantial advances in text-based reasoning, even state-of-the-art models such as GPT-o3 struggle to maintain strong performance in multimodal…

Computation and Language · Computer Science 2025-09-09 Hao Liang , Ruitao Wu , Bohan Zeng , Junbo Niu , Wentao Zhang , Bin Dong

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

Computation and Language · Computer Science 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

Medical reasoning models remain constrained by parametric knowledge and are thus susceptible to forgetting and hallucinations. DeepResearch (DR) models ground outputs in verifiable evidence from tools and perform strongly in general…

Artificial Intelligence · Computer Science 2026-02-05 Zihan Wang , Hao Wang , Shi Feng , Xiaocui Yang , Daling Wang , Yiqun Zhang , Jinghao Lin , Haihua Yang , Xiaozhong Ji

The benefits of artificial intelligence (AI) human partnerships-evaluating how AI agents enhance expert human performance-are increasingly studied. Though rarely evaluated in healthcare, an inverse approach is possible: AI benefiting from…

With the development of generative artificial intelligence and instruction tuning techniques, multimodal large language models (MLLMs) have made impressive progress on general reasoning tasks. Benefiting from the chain-of-thought (CoT)…

Machine Learning · Computer Science 2025-07-03 Junjie Zhou , Yingli Zuo , Shichang Feng , Peng Wan , Qi Zhu , Daoqiang Zhang , Wei Shao

This study proposes a novel approach combining Multimodal Deep Learning with intrinsic eXplainable Artificial Intelligence techniques to predict pathological response in non-small cell lung cancer patients undergoing neoadjuvant therapy.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Alice Natalina Caragliano , Claudia Tacconi , Carlo Greco , Lorenzo Nibid , Edy Ippolito , Michele Fiore , Giuseppe Perrone , Sara Ramella , Paolo Soda , Valerio Guarrasi

Large language models (LLMs), particularly those with reasoning capabilities, have rapidly advanced in recent years, demonstrating significant potential across a wide range of applications. However, their deployment in healthcare,…

Artificial Intelligence · Computer Science 2025-02-27 Guoxin Wang , Minyu Gao , Shuai Yang , Ya Zhang , Lizhi He , Liang Huang , Hanlin Xiao , Yexuan Zhang , Wanyue Li , Lu Chen , Jintao Fei , Xin Li

Machine learning has emerged as a powerful tool for scientific discovery, enabling researchers to extract meaningful insights from complex datasets. For instance, it has facilitated the identification of disease-predictive genes from gene…

Artificial intelligence has started to transform histopathology impacting clinical diagnostics and biomedical research. However, while many computational pathology approaches have been proposed, most current AI models are limited with…

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Healthcare simulations help learners develop teamwork and clinical skills in a risk-free setting, promoting reflection on real-world practices through structured debriefs. However, despite video's potential, it is hard to use, leaving a gap…

Young people's mental well-being is a global concern, with peer support playing a key role in daily emotional regulation. Conversational agents are increasingly viewed as promising tools for delivering accessible, personalised peer support,…

Human-Computer Interaction · Computer Science 2025-12-01 Ruoyu Wen , Xiaoli Wu , Kunal Gupta , Simon Hoermann , Mark Billinghurst , Alaeddin Nassani , Dwain Allan , Thammathip Piumsomboon

In the dynamic landscape of Industry 4.0, achieving efficiency, precision, and adaptability is essential to optimize manufacturing operations. Industries suffer due to supply chain disruptions caused by anomalies, which are being detected…

Artificial Intelligence · Computer Science 2025-05-13 Chathurangi Shyalika , Renjith Prasad , Alaa Al Ghazo , Darssan Eswaramoorthi , Harleen Kaur , Sara Shree Muthuselvam , Amit Sheth

Manually annotated data is key to developing text-mining and information-extraction algorithms. However, human annotation requires considerable time, effort and expertise. Given the rapid growth of biomedical literature, it is paramount to…

Human-Computer Interaction · Computer Science 2020-04-27 Rezarta Islamaj , Dongseop Kwon , Sun Kim , Zhiyong Lu

Progress in biomedical Named Entity Recognition (NER) and Entity Linking (EL) is currently hindered by a fragmented data landscape, a lack of resources for building explainable models, and the limitations of semantically-blind evaluation…

Computation and Language · Computer Science 2025-11-17 Nishant Mishra , Wilker Aziz , Iacer Calixto

Motivation: Digitization of pathology laboratories through digital slide scanners and advances in deep learning approaches for objective histological assessment have resulted in rapid progress in the field of computational pathology (CPath)…

Machine Learning · Computer Science 2022-01-31 Alex Foote , Amina Asif , Nasir Rajpoot , Fayyaz Minhas

Digital pathology plays a crucial role in the development of artificial intelligence in the medical field. The digital pathology platform can make the pathological resources digital and networked, and realize the permanent storage of visual…

Human-Computer Interaction · Computer Science 2021-11-11 Jialun Wu , Anyu Mao , Xinrui Bao , Haichuan Zhang , Zeyu Gao , Chunbao Wang , Tieliang Gong , Chen Li
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