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Pathological diagnosis remains the definitive standard for identifying tumors. The rise of multimodal large models has simplified the process of integrating image analysis with textual descriptions. Despite this advancement, the substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Xiaomin Wu , Rui Xu , Pengchen Wei , Wenkang Qin , Peixiang Huang , Ziheng Li , Lin Luo

Remarkable success of modern image-based AI methods and the resulting interest in their applications in critical decision-making processes has led to a surge in efforts to make such intelligent systems transparent and explainable. The need…

Artificial Intelligence · Computer Science 2020-11-30 Adriano Lucieri , Muhammad Naseer Bajwa , Andreas Dengel , Sheraz Ahmed

Diagnosing hepatic diseases accurately and interpretably is critical, yet it remains challenging in real-world clinical settings. Existing AI approaches for clinical diagnosis often lack transparency, structured reasoning, and…

Artificial Intelligence · Computer Science 2026-03-06 Zheng Li , Jiayi Xu , Zhikai Hu , Hechang Chen , Lele Cong , Yunyun Wang , Shuchao Pang

The increasing prevalence of retinal diseases poses a significant challenge to the healthcare system, as the demand for ophthalmologists surpasses the available workforce. This imbalance creates a bottleneck in diagnosis and treatment,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Jia-Hong Huang

Artificial intelligence has demonstrated significant potential in clinical decision-making; however, developing models capable of adapting to diverse real-world scenarios and performing complex diagnostic reasoning remains a major…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Ronghao Xu , Zhen Huang , Yangbo Wei , Xiaoqian Zhou , Zikang Xu , Ting Liu , Zihang Jiang , S. Kevin Zhou

Inpatient pathways demand complex clinical decision-making based on comprehensive patient information, posing critical challenges for clinicians. Despite advancements in large language models (LLMs) in medical applications, limited research…

Artificial Intelligence · Computer Science 2025-03-18 Zhen Chen , Zhihao Peng , Xusheng Liang , Cheng Wang , Peigan Liang , Linsheng Zeng , Minjie Ju , Yixuan Yuan

The application of large language models (LLMs) in clinical decision support faces significant challenges of "tunnel vision" and diagnostic hallucinations present in their processing unstructured electronic health records (EHRs). To address…

Artificial Intelligence · Computer Science 2026-04-28 Zhiqi Lv , Duofan Tu , Jun Li , Mingyue Zhao , Heqin Zhu , Wenliang Li , Shaohua Kevin Zhou

Explainable AI aims to render model behavior understandable by humans, which can be seen as an intermediate step in extracting causal relations from correlative patterns. Due to the high risk of possible fatal decisions in image-based…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Lukas Klein , João B. S. Carvalho , Mennatallah El-Assady , Paolo Penna , Joachim M. Buhmann , Paul F. Jaeger

Healthcare requires AI that is predictive, reliable, and data-efficient. However, recent generative models lack physical foundation and temporal reasoning required for clinical decision support. As scaling language models show diminishing…

Machine Learning · Computer Science 2025-11-21 Mohammad Areeb Qazi , Maryam Nadeem , Mohammad Yaqub

Although Vision Language Models (VLMs) have shown strong generalization in medical imaging, pathology presents unique challenges due to ultra-high resolution, complex tissue structures, and nuanced clinical semantics. These factors make…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Wenchuan Zhang , Jingru Guo , Hengzhe Zhang , Penghao Zhang , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu

Misdiagnosis causes significant harm to healthcare systems worldwide, leading to increased costs and patient risks. MedRAG is a smart multimodal healthcare copilot equipped with powerful large language model (LLM) reasoning, designed to…

Artificial Intelligence · Computer Science 2025-06-04 Xuejiao Zhao , Siyan Liu , Su-Yin Yang , Chunyan Miao

Unified multimodal models (UMMs) aim to integrate understanding and generation within a single architecture. However, it remains underexplored how to effectively coordinate these two capabilities for more effective and efficient reasoning.…

Multimedia · Computer Science 2026-05-13 Hayes Bai , Yinyi Luo , Wenwen Wang , Qingsong Wen , Jindong Wang

As advances in large language models (LLMs) and multimodal techniques continue to mature, the development of general-purpose multimodal large language models (MLLMs) has surged, offering significant applications in interpreting natural…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Yuxuan Sun , Chenglu Zhu , Sunyi Zheng , Kai Zhang , Lin Sun , Zhongyi Shui , Yunlong Zhang , Honglin Li , Lin Yang

The Human-Autonomy Teaming paradigm (HAT) has recently emerged to model and design hybrid teams, where a human operator must cooperate with an artificial agent, able to independently evolve in dynamic and uncertain situations. An important…

Human-Computer Interaction · Computer Science 2023-01-18 Philippe Rauffet

Computational pathology demands both visual pattern recognition and dynamic integration of structured domain knowledge, including taxonomy, grading criteria, and clinical evidence. In practice, diagnostic reasoning requires linking…

Artificial Intelligence · Computer Science 2026-05-26 Jinyue Li , Yuci Liang , Qiankun Li , Xinheng Lyu , Jiayu Qian , Huabao Chen , Kun Wang , Zhigang Zeng , Anil Anthony Bharath , Yang Liu

In this paper we propose an advanced approach to integrating artificial intelligence (AI) into healthcare: autonomous decision support. This approach allows the AI algorithm to act autonomously for a subset of patient cases whilst serving a…

Artificial Intelligence · Computer Science 2025-03-25 Yan Jia , Harriet Evans , Zoe Porter , Simon Graham , John McDermid , Tom Lawton , David Snead , Ibrahim Habli

This literature review involves the use of AI communication facilitators to detect mood disorders such as bipolar disorder, a psychiatric condition in which patients experience drastic mood shifts. Due to the ill-defined nature of the…

Human-Computer Interaction · Computer Science 2023-04-18 Trisha Guttal

Effective teamwork is essential across diverse domains. During the team formation stage, a key challenge is forming teams that effectively balance user preferences with task objectives to enhance overall team satisfaction. In the team…

Human-Computer Interaction · Computer Science 2025-06-09 Mohammed Almutairi

Artificial intelligence (AI)-enabled diagnostics in maxillofacial pathology require structured, high-quality multimodal datasets. However, existing resources provide limited ameloblastoma coverage and lack the format consistency needed for…

Artificial Intelligence · Computer Science 2026-02-06 Ajo Babu George , Anna Mariam John , Athul Anoop , Balu Bhasuran

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…