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The landscape of publicly available vision foundation models (VFMs), such as CLIP and Segment Anything Model (SAM), is expanding rapidly. VFMs are endowed with distinct capabilities stemming from their pre-training objectives. For instance,…

We present ENSAM (Equivariant, Normalized, Segment Anything Model), a lightweight and promptable model for universal 3D medical image segmentation. ENSAM combines a SegResNet-based encoder with a prompt encoder and mask decoder in a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Elias Stenhede , Agnar Martin Bjørnstad , Arian Ranjbar

The Segment Anything Model (SAM) is a powerful foundation model for image segmentation, showing robust zero-shot generalization through prompt engineering. However, relying on manual prompts is impractical for real-world applications,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Yi Chen , Mu-Young Son , Chuanbo Hua , Joo-Young Kim

In digital pathology, precise nuclei segmentation is pivotal yet challenged by the diversity of tissue types, staining protocols, and imaging conditions. Recently, the segment anything model (SAM) revealed overwhelming performance in…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Zhen Chen , Qing Xu , Xinyu Liu , Yixuan Yuan

The development of 2D foundation models for image segmentation has been significantly advanced by the Segment Anything Model (SAM). However, achieving similar success in 3D models remains a challenge due to issues such as non-unified data…

Computer Vision and Pattern Recognition · Computer Science 2024-12-04 Yuchen Zhou , Jiayuan Gu , Tung Yen Chiang , Fanbo Xiang , Hao Su

The Segment Anything Model (SAM) is a powerful foundation model that has revolutionised image segmentation. To apply SAM to surgical instrument segmentation, a common approach is to locate precise points or boxes of instruments and then use…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Wenxi Yue , Jing Zhang , Kun Hu , Yong Xia , Jiebo Luo , Zhiyong Wang

The recently introduced Segment Anything Model (SAM), a Visual Foundation Model (VFM), has demonstrated impressive capabilities in zero-shot segmentation tasks across diverse natural image datasets. Despite its success, SAM encounters…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Chunpeng Zhou , Kangjie Ning , Qianqian Shen , Sheng Zhou , Zhi Yu , Haishuai Wang

Segment Anything Model (SAM), a new AI model from Meta AI released in April 2023, is an ambitious tool designed to identify and separate individual objects within a given image through semantic interpretation. The advanced capabilities of…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Gabriel Bellon de Carvalho , Jurandy Almeida

The Segment Anything Model (SAM) has recently emerged as a groundbreaking foundation model for prompt-driven image segmentation tasks. However, both the original SAM and its medical variants require slice-by-slice manual prompting of target…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yichi Zhang , Shiyao Hu , Sijie Ren , Chen Jiang , Yuan Cheng , Yuan Qi

The Foundation model for image segmentation, Segment Anything (SAM), has been actively researched in various fields since its proposal. Various researches have been proposed to adapt SAM to specific domains, with one notable approach…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Joohyeok Kim , Joonhyeon Song , Seohwan Yun , Seongho Yoon , Sangmin Lee

Although the Segment Anything Model (SAM) is highly effective in natural image segmentation, it requires dependencies on prompts, which limits its applicability to medical imaging where manual prompts are often unavailable. Existing efforts…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Mengmeng Zhang , Xingyuan Dai , Yicheng Sun , Jing Wang , Yueyang Yao , Xiaoyan Gong , Fuze Cong , Feiyue Wang , Yisheng Lv

Tracking cells and detecting mitotic events in time-lapse microscopy image sequences is a crucial task in biomedical research. However, it remains highly challenging due to dividing objects, low signal-tonoise ratios, indistinct boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Zhu Chen , Mert Edgü , Er Jin , Johannes Stegmaier

Medical image segmentation models built on Segment Anything Model (SAM) achieve strong performance on clean benchmarks, yet their reliability often degrades under realistic image corruptions such as noise, blur, motion artifacts, and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Jieru Li , Matthew Chen , Micky C. Nnamdi , J. Ben Tamo , Benoit L. Marteau , May D. Wang

Semantic segmentation is a fundamental task in medical image analysis and autonomous driving and has a problem with the high cost of annotating the labels required in training. To address this problem, semantic segmentation methods based on…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Nagito Saito , Shintaro Ito , Koichi Ito , Takafumi Aoki

Segment Anything Model (SAM) represents a large-scale segmentation model that enables powerful zero-shot capabilities with flexible prompts. While SAM can segment any object in zero-shot, it requires user-provided prompts for each target…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Kosuke Sakurai , Ryotaro Shimizu , Masayuki Goto

Leveraging pre-trained models with tailored prompts for in-context learning has proven highly effective in NLP tasks. Building on this success, recent studies have applied a similar approach to the Segment Anything Model (SAM) within a…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Hangyul Yoon , Doohyuk Jang , Jungeun Kim , Eunho Yang

The Segment Anything Model (SAM) is a foundation model for general image segmentation. Although it exhibits impressive performance predominantly on natural images, understanding its robustness against various image perturbations and domains…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Yuqing Wang , Yun Zhao , Linda Petzold

The Segment Anything Model (SAM) has exhibited outstanding performance in various image segmentation tasks. Despite being trained with over a billion masks, SAM faces challenges in mask prediction quality in numerous scenarios, especially…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhaozhi Xie , Bochen Guan , Weihao Jiang , Muyang Yi , Yue Ding , Hongtao Lu , Lei Zhang

The Segment Anything Model (SAM) has recently emerged as a significant breakthrough in foundation models, demonstrating remarkable zero-shot performance in object segmentation tasks. While SAM is designed for generalization, it exhibits…

Computer Vision and Pattern Recognition · Computer Science 2023-12-15 Josh Stein , Maxime Di Folco , Julia A. Schnabel

Promptable segmentation foundation models have emerged as a transformative approach to addressing the diverse needs in medical images, but most existing models require expensive computing, posing a big barrier to their adoption in clinical…