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This paper presents a weakly supervised image segmentation method that adopts tight bounding box annotations. It proposes generalized multiple instance learning (MIL) and smooth maximum approximation to integrate the bounding box tightness…

Computer Vision and Pattern Recognition · Computer Science 2021-10-25 Juan Wang , Bin Xia

Vision language models (VLM) pre-trained on datasets of histopathological image-caption pairs enabled zero-shot slide-level classification. The ability of VLM image encoders to extract discriminative features also opens the door for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Multiple instance learning is qualified for many pattern recognition tasks with weakly annotated data. The combination of artificial neural network and multiple instance learning offers an end-to-end solution and has been widely utilized.…

Computer Vision and Pattern Recognition · Computer Science 2022-05-30 Jingjun Yi , Beichen Zhou

Multiple instance learning (MIL) aims to learn the mapping between a bag of instances and the bag-level label. In this paper, we propose a new end-to-end graph neural network (GNN) based algorithm for MIL: we treat each bag as a graph and…

Machine Learning · Computer Science 2019-06-13 Ming Tu , Jing Huang , Xiaodong He , Bowen Zhou

In-context learning (ICL) with Large Vision Models (LVMs) presents a promising avenue in medical image segmentation by reducing the reliance on extensive labeling. However, the ICL performance of LVMs highly depends on the choices of visual…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Chenwei Wu , David Restrepo , Zitao Shuai , Zhongming Liu , Liyue Shen

We present Variational Self-Supervised Learning (VSSL), a novel framework that combines variational inference with self-supervised learning to enable efficient, decoder-free representation learning. Unlike traditional VAEs that rely on…

Machine Learning · Computer Science 2025-05-02 Mehmet Can Yavuz , Berrin Yanikoglu

Transformer-based language models display impressive reasoning-like behavior, yet remain brittle on tasks that require stable symbolic manipulation. This paper develops a unified perspective on these phenomena by interpreting self-attention…

Artificial Intelligence · Computer Science 2025-12-18 Sahil Rajesh Dhayalkar

Data scarcity and weak supervision continue to limit the performance of machine learning models in many real-world applications, such as mammography, where Multiple Instance Learning (MIL) often offers the best formulation. While recent…

Machine Learning · Computer Science 2026-04-21 Nikola Jovišić , Milica Škipina , Vanja Švenda

Machine learning (ML) models are constructed by expert ML practitioners using various coding languages, in which they tune and select models hyperparameters and learning algorithms for a given problem domain. They also carefully design an…

Machine Learning · Computer Science 2021-03-16 Subhajit Das , Alex Endert

In this paper, we address the Multi-Instance-Learning (MIL) problem when bag labels are naturally represented as ordinal variables (Multi--Instance--Ordinal Regression). Moreover, we consider the case where bags are temporal sequences of…

Computer Vision and Pattern Recognition · Computer Science 2016-09-07 Adria Ruiz , Ognjen Rudovic , Xavier Binefa , Maja Pantic

When supervising an object detector with weakly labeled data, most existing approaches are prone to trapping in the discriminative object parts, e.g., finding the face of a cat instead of the full body, due to lacking the supervision on the…

Computer Vision and Pattern Recognition · Computer Science 2017-11-28 Siyang Li , Xiangxin Zhu , Qin Huang , Hao Xu , C. -C. Jay Kuo

Multiple instance learning (MIL) has emerged as a powerful framework for weakly supervised whole slide image (WSI) classification, enabling slide-level predictions without requiring detailed patch-level annotations. Despite its success, a…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Bryan Wong , Mun Yong Yi

Hispathological image segmentation algorithms play a critical role in computer aided diagnosis technology. The development of weakly supervised segmentation algorithm alleviates the problem of medical image annotation that it is…

Computer Vision and Pattern Recognition · Computer Science 2022-05-19 Ziniu Qian , Kailu Li , Maode Lai , Eric I-Chao Chang , Bingzheng Wei , Yubo Fan , Yan Xu

In this paper, we present a new multiple instance learning (MIL) method, called MIS-Boost, which learns discriminative instance prototypes by explicit instance selection in a boosting framework. Unlike previous instance selection based MIL…

Machine Learning · Computer Science 2011-09-13 Emre Akbas , Bernard Ghanem , Narendra Ahuja

Both masked image modeling (MIM) and natural language supervision have facilitated the progress of transferable visual pre-training. In this work, we seek the synergy between two paradigms and study the emerging properties when MIM meets…

Computer Vision and Pattern Recognition · Computer Science 2023-03-01 Shusheng Yang , Yixiao Ge , Kun Yi , Dian Li , Ying Shan , Xiaohu Qie , Xinggang Wang

Multiple instance learning (MIL) is a robust paradigm for whole-slide pathological image (WSI) analysis, processing gigapixel-resolution images with slide-level labels. As pioneering efforts, attention-based MIL (ABMIL) and its variants are…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Linghan Cai , Shenjin Huang , Ye Zhang , Jinpeng Lu , Yongbing Zhang

This paper presents a simple unsupervised visual representation learning method with a pretext task of discriminating all images in a dataset using a parametric, instance-level classifier. The overall framework is a replica of a supervised…

Computer Vision and Pattern Recognition · Computer Science 2021-02-10 Yu Liu , Lianghua Huang , Pan Pan , Bin Wang , Yinghui Xu , Rong Jin

State-of-the-art visual recognition and detection systems increasingly rely on large amounts of training data and complex classifiers. Therefore it becomes increasingly expensive both to manually annotate datasets and to keep running times…

Computer Vision and Pattern Recognition · Computer Science 2014-12-02 Stefan Mathe , Cristian Sminchisescu

Symbolic reasoning and neural networks are often considered incompatible approaches. Connectionist models known as Vector Symbolic Architectures (VSAs) can potentially bridge this gap. However, classical VSAs and neural networks are still…

Neural and Evolutionary Computing · Computer Science 2020-09-16 E. Paxon Frady , Denis Kleyko , Friedrich T. Sommer

While multiple instance learning (MIL) has shown to be a promising approach for histopathological whole slide image (WSI) analysis, its reliance on permutation invariance significantly limits its capacity to effectively uncover semantic…

Image and Video Processing · Electrical Eng. & Systems 2025-07-14 Xiwen Chen , Peijie Qiu , Wenhui Zhu , Hao Wang , Huayu Li , Xuanzhao Dong , Xiaotong Sun , Xiaobing Yu , Yalin Wang , Abolfazl Razi , Aristeidis Sotiras