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Traditional neuroimage analysis pipelines involve computationally intensive, time-consuming optimization steps, and thus, do not scale well to large cohort studies with thousands or tens of thousands of individuals. In this work we propose…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Leonie Henschel , Sailesh Conjeti , Santiago Estrada , Kersten Diers , Bruce Fischl , Martin Reuter

Structural alterations of the midsagittal corpus callosum (midCC) have been associated with a wide range of brain disorders. The midCC is visible on most MRI contrasts and in many acquisitions with a limited field-of-view. Here, we present…

The corpus callosum, the largest white matter structure in the brain, plays a critical role in interhemispheric communication. Variations in its morphology are associated with various neurological and psychological conditions, making it a…

Applications · Statistics 2025-03-05 Zhe Gao , Jin Zhu , Yue Hu , Wenliang Pan , Xueqin Wang

The study of neurodegenerative diseases relies on the reconstruction and analysis of the brain cortex from magnetic resonance imaging (MRI). Traditional frameworks for this task like FreeSurfer demand lengthy runtimes, while its accelerated…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Rodrigo Santa Cruz , Leo Lebrat , Pierrick Bourgeat , Clinton Fookes , Jurgen Fripp , Olivier Salvado

The claustrum (Cl) is a thin grey matter structure located in the center of each brain hemisphere. Cl has been hypothesized as a central hub of the brain for multisensory/sensorimotor integration, consciousness, and attention. Accumulating…

Quantitative Methods · Quantitative Biology 2020-10-14 Seung Suk Kang , Joseph Bodenheimer , Tracey Butler

Subcortical segmentation remains challenging despite its important applications in quantitative structural analysis of brain MRI scans. The most accurate method, manual segmentation, is highly labor intensive, so automated tools like…

Image and Video Processing · Electrical Eng. & Systems 2025-10-17 Aaron Cao , Vishwanatha M. Rao , Kejia Liu , Xinrui Liu , Andrew F. Laine , Jia Guo

Structural MRI(S-MRI) is one of the most versatile imaging modality that revolutionized the anatomical study of brain in past decades. The corpus callosum (CC) is the principal white matter fibre tract, enabling all kinds of…

Image and Video Processing · Electrical Eng. & Systems 2023-06-02 Vamshi Krishna Kancharla , Debanjali Bhattacharya , Neelam Sinha , Jitender Saini , Pramod Kumar Pal , Sandhya M

The hypothalamus plays a crucial role in the regulation of a broad range of physiological, behavioural, and cognitive functions. However, despite its importance, only a few small-scale neuroimaging studies have investigated its…

Computer Vision and Pattern Recognition · Computer Science 2023-11-08 Santiago Estrada , David Kügler , Emad Bahrami , Peng Xu , Dilshad Mousa , Monique M. B. Breteler , N. Ahmad Aziz , Martin Reuter

Computer vision and machine learning are the linchpin of field of automation. The medicine industry has adopted numerous methods to discover the root causes of many diseases in order to automate detection process. But, the biomarkers of…

Computer Vision and Pattern Recognition · Computer Science 2021-11-29 Hamza Sharif , Rizwan Ahmed Khan

Accurate fetal brain segmentation is crucial for extracting biomarkers and assessing neurodevelopment, especially in conditions such as corpus callosum dysgenesis (CCD), which can induce drastic anatomical changes. However, the rarity of…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Marina Grifell i Plana , Vladyslav Zalevskyi , Léa Schmidt , Yvan Gomez , Thomas Sanchez , Vincent Dunet , Mériam Koob , Vanessa Siffredi , Meritxell Bach Cuadra

Quantitative, volumetric analysis of Magnetic Resonance Imaging (MRI) is a fundamental way researchers study the brain in a host of neurological conditions including normal maturation and aging. Despite the availability of open-source brain…

Quantitative Methods · Quantitative Biology 2019-11-15 Aakash Kaku , Chaitra V. Hegde , Jeffrey Huang , Sohae Chung , Xiuyuan Wang , Matthew Young , Alireza Radmanesh , Yvonne W. Lui , Narges Razavian

The claustrum is a thin gray matter structure in each brain hemisphere, characterized by exceptionally high connectivity with nearly all brain regions. Despite extensive animal studies on its anatomy and function and growing evidence of…

Neurons and Cognition · Quantitative Biology 2025-05-16 Steven Seung-Suk Kang , Joseph Bodenheimer , Kayley Morris , Tracey Butler

Accurate and reproducible brain morphometry from structural MRI is critical for monitoring neuroanatomical changes across time and across imaging domains. Although deep learning has accelerated segmentation workflows, scanner-induced…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Ekaterina Kondrateva , Sandzhi Barg , Mikhail Vasiliev

Accurate delineation of anatomical structures in volumetric CT scans is crucial for diagnosis and treatment planning. While AI has advanced automated segmentation, current approaches typically target individual structures, creating a…

Many functional and structural neuroimaging studies call for accurate morphometric segmentation of different brain structures starting from image intensity values of MRI scans. Current automatic (multi-) atlas-based segmentation strategies…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Dennis Bontempi , Sergio Benini , Alberto Signoroni , Michele Svanera , Lars Muckli

We present a deep learning segmentation model that can automatically and robustly segment all major anatomical structures in body CT images. In this retrospective study, 1204 CT examinations (from the years 2012, 2016, and 2020) were used…

Determining brain hemodynamics plays a critical role in the diagnosis and treatment of various cerebrovascular diseases. In this work, we put forth a physics-informed deep learning framework that augments sparse clinical measurements with…

Medical Physics · Physics 2021-08-27 Mohammad Sarabian , Hessam Babaee , Kaveh Laksari

Whole brain segmentation and cortical surface parcellation are essential in understanding the anatomical-functional relationships of the brain. Multi-atlas segmentation has been regarded as one of the leading segmentation methods for the…

Computer Vision and Pattern Recognition · Computer Science 2017-12-05 Yuankai Huo , Shunxing Bao , Prasanna Parvathaneni , Bennett A. Landman

Transcranial focused ultrasound (tFUS) is an emerging modality for non-invasive brain stimulation and therapeutic intervention, offering millimeter-scale spatial precision and the ability to target deep brain structures. However, the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Vinkle Srivastav , Juliette Puel , Jonathan Vappou , Elijah Van Houten , Paolo Cabras , Nicolas Padoy

Cardiac ultrasound (US) scanning is a commonly used techniques in cardiology to diagnose the health of the heart and its proper functioning. Therefore, it is necessary to consider ways to automate these tasks and assist medical…

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