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Realistic description of patient-specific mechanical properties of clotting dynamics presents a major challenge. Available patient-specific data falls short of robustly characterizing myriads of complex dynamic interactions that happen…

Molecular Networks · Quantitative Biology 2017-05-23 Jayavel Arumugam , Arun Srinivasa

Multiscale dynamics are ubiquitous in applications of modern science. Because of time scale separation between relatively small set of slowly evolving variables and (typically) much larger set of rapidly changing variables, direct numerical…

Dynamical Systems · Mathematics 2016-04-08 Rafail V. Abramov

In this paper we study how all the physical "constants" vary in the framework described by a model in which we have taken into account the generalize conservation principle for its stress-energy tensor. This possibility enable us to take…

General Relativity and Quantum Cosmology · Physics 2009-11-07 José Antonio Belinchón

Modeling and parameter estimation for neuronal dynamics are often challenging because many parameters can range over orders of magnitude and are difficult to measure experimentally. Moreover, selecting a suitable model complexity requires a…

Dynamical Systems · Mathematics 2018-01-31 J. E. Rubin , B. Krauskopf , H. M. Osinga

Simple analytic considerations are applied to recently discovered patterns in a generalized Fisher equation for population dynamics. The generalization consists of the inclusion of non-local competition interactions among individuals. We…

Pattern Formation and Solitons · Physics 2007-05-23 M. A. Fuentes , M. N. Kuperman , V. M. Kenkre

Understanding how the brain learns to compute functions reliably, efficiently and robustly with noisy spiking activity is a fundamental challenge in neuroscience. Most sensory and motor tasks can be described as dynamical systems and could…

Neurons and Cognition · Quantitative Biology 2017-05-24 Sophie Denève , Alireza Alemi , Ralph Bourdoukan

We consider a fully-connected network of leaky integrate-and-fire neurons with spike-timing-dependent plasticity. The plasticity is controlled by a parameter representing the expected weight of a synapse between neurons that are firing…

Neurons and Cognition · Quantitative Biology 2011-09-23 Chun-Chung Chen , David Jasnow

We consider a population dynamics model coupling cell growth to a diffusion in the space of metabolic phenotypes as it can be obtained from realistic constraints-based modelling. In the asymptotic regime of slow diffusion, that coincides…

Populations and Evolution · Quantitative Biology 2017-02-17 Daniele De Martino , Davide Masoero

Asynchrony, overlaps and delays in sensory-motor signals introduce ambiguity as to which stimuli, actions, and rewards are causally related. Only the repetition of reward episodes helps distinguish true cause-effect relationships from…

Neural and Evolutionary Computing · Computer Science 2014-09-10 Andrea Soltoggio

Graphical models are an important tool in exploring relationships between variables in complex, multivariate data. Methods for learning such graphical models are well developed in the case where all variables are either continuous or…

Machine Learning · Statistics 2024-02-15 Konstantin Göbler , Anne Miloschewski , Mathias Drton , Sach Mukherjee

The Cyclic Model attempts to resolve the homogeneity, isotropy, and flatness problems and generate a nearly scale-invariant spectrum of fluctuations during a period of slow contraction that precedes a bounce to an expanding phase. Here we…

Astrophysics · Physics 2009-09-15 Paul J. Steinhardt , Neil Turok

In this paper we study the dynamics of the general case of Owen-Smith metaphysiological model, to explore the effects of seasonality on population fluctuations. The study will include the permanence, herbivore extinction, global asymptotic…

Dynamical Systems · Mathematics 2011-01-11 Mohamed Bakheet , Henri Laurie

We consider a periodically driven system where the high-frequency driving protocol consists of a sequence of potentials switched on and off at different instants within a period. We explore the possibility of introducing an adiabatic…

Quantum Physics · Physics 2025-02-26 Ashwin Murali , Tapomoy Guha Sarkar , Jayendra N. Bandyopadhyay

In randomized clinical trials, adjusting for baseline covariates can improve credibility and efficiency for demonstrating and quantifying treatment effects. This article studies the augmented inverse propensity weighted (AIPW) estimator,…

Methodology · Statistics 2024-03-27 Marlena S. Bannick , Jun Shao , Jingyi Liu , Yu Du , Yanyao Yi , Ting Ye

We extend the theory of weakly coupled oscillators to incorporate slowly varying inputs and parameters. We employ a combination of regular perturbation and an adiabatic approximation to derive equations for the phase-difference between a…

Dynamical Systems · Mathematics 2016-03-09 Youngmin Park , Bard Ermentrout

Realistic networks display heterogeneous transmission delays. We analyze here the limits of large stochastic multi-populations networks with stochastic coupling and random interconnection delays. We show that depending on the nature of the…

Mathematical Physics · Physics 2015-12-15 Jonathan Touboul

We generalize Kato's adiabatic theorem to nonunitary dynamics with an isospectral generator. This enables us to unify two strong-coupling limits: one driven by fast oscillations under a Hamiltonian, and the other driven by strong damping…

Quantum Physics · Physics 2019-06-20 Daniel Burgarth , Paolo Facchi , Hiromichi Nakazato , Saverio Pascazio , Kazuya Yuasa

We consider the behavior of a collective variable in a complex system formed by a finite number of interacting subunits. Each of them is characterized by a degree of freedom with an intrinsic nonlinear bistable stochastic dynamics. The lack…

Statistical Mechanics · Physics 2017-03-16 M. Morillo , J. M. Casado

Copulas, generalized estimating equations, and generalized linear mixed models promote the analysis of grouped data where non-normal responses are correlated. Unfortunately, parameter estimation remains challenging in these three…

Methodology · Statistics 2024-10-16 Sarah S. Ji , Benjamin B. Chu , Hua Zhou , Kenneth Lange

Finding coarse-grained, low-dimensional descriptions is an important task in the analysis of complex, stochastic models of gene regulatory networks. This task involves (a) identifying observables that best describe the state of these…

Quantitative Methods · Quantitative Biology 2015-06-26 Radek Erban , Thomas A. Frewen , Xiao Wang , Timothy C. Elston , Ronald Coifman , Boaz Nadler , Ioannis G. Kevrekidis
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