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Medical coding translates free-text clinical documentation into standardized codes drawn from classification systems that contain tens of thousands of entries and are updated annually. It is central to billing, clinical research, and…

Artificial Intelligence · Computer Science 2026-04-01 Joakim Edin , Andreas Motzfeldt , Simon Flachs , Lars Maaløe

Clinical coding is the task of transforming medical information in a patient's health records into structured codes so that they can be used for statistical analysis. This is a cognitive and time-consuming task that follows a standard…

Computation and Language · Computer Science 2022-10-11 Hang Dong , Matúš Falis , William Whiteley , Beatrice Alex , Joshua Matterson , Shaoxiong Ji , Jiaoyan Chen , Honghan Wu

Clinical reasoning agents based on large language models (LLMs) aim to automate tasks such as intensive care unit (ICU) monitoring and patient state tracking from electronic health records (EHRs). Existing systems typically rely on manually…

Artificial Intelligence · Computer Science 2026-05-12 Timothy Ossowski , Xinchi Liu , Danyal Maqbool , Vaibhav Dhanuka , Sheng Zhang , Hoifung Poon , Majid Afshar , Tyler Bradshaw , Junjie Hu

Modern clinical practice relies on evidence-based guidelines implemented as compact scoring systems composed of a small number of interpretable decision rules. While machine-learning models achieve strong performance, many fail to translate…

Machine Learning · Computer Science 2026-05-25 Silas Ruhrberg Estévez , Christopher Chiu , Mihaela van der Schaar

There are several opportunities for automation in healthcare that can improve clinician throughput. One such example is assistive tools to document diagnosis codes when clinicians write notes. We study the automation of medical code…

Machine Learning · Computer Science 2022-08-05 Weiming Ren , Ruijing Zeng , Tongzi Wu , Tianshu Zhu , Rahul G. Krishnan

Large Language Model (LLM)-based agents have demonstrated strong capabilities across a wide range of tasks, and their application in the medical domain holds particular promise due to the demand for high generalizability and reliance on…

Artificial Intelligence · Computer Science 2025-08-18 Yangyang Zhuang , Wenjia Jiang , Jiayu Zhang , Ze Yang , Joey Tianyi Zhou , Chi Zhang

Vision-language models (VLMs) have shown potential for automated radiology report generation, yet existing approaches rely on global embedding compression of volumetric data, often leading to hallucinated findings and limited anatomical…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Giuseppe A. Orlando , Paolo Papotti , Maria A. Zuluaga , Olivier Humbert , Marco Lorenzi

Clinical coding is crucial for healthcare billing and data analysis. Manual clinical coding is labour-intensive and error-prone, which has motivated research towards full automation of the process. However, our analysis, based on US English…

Computation and Language · Computer Science 2025-06-19 Yidong Gan , Maciej Rybinski , Ben Hachey , Jonathan K. Kummerfeld

Medical coding, the translation of unstructured clinical text into standardized medical codes, is a crucial but time-consuming healthcare practice. Though large language models (LLM) could automate the coding process and improve the…

Computation and Language · Computer Science 2025-03-25 John Wu , David Wu , Jimeng Sun

Clinical data-driven research requires clinical expertise, programming skills, access to patient data, and extensive documentation, creating barriers and slowing the pace for clinicians and external researchers. To address this, we…

Computation and Language · Computer Science 2026-04-22 Taehun Kim , Hyeryun Park , Hyeonhoon Lee , Yushin Lee , Kyungsang Kim , Hyung-Chul Lee

Medical texts, particularly electronic medical records (EMRs), are a cornerstone of modern healthcare, capturing critical information about patient care, diagnoses, and treatments. These texts hold immense potential for advancing clinical…

Computation and Language · Computer Science 2025-11-12 Mucheng Ren , Yucheng Yan , He Chen , Danqing Hu , Jun Xu , Xian Zeng

Automated medical coding, an essential task for healthcare operation and delivery, makes unstructured data manageable by predicting medical codes from clinical documents. Recent advances in deep learning and natural language processing have…

Computation and Language · Computer Science 2024-05-15 Shaoxiong Ji , Wei Sun , Xiaobo Li , Hang Dong , Ara Taalas , Yijia Zhang , Honghan Wu , Esa Pitkänen , Pekka Marttinen

Molecular dynamics (MD) simulations are essential for understanding biomolecular systems but remain challenging to automate. Recent advances in large language models (LLM) have demonstrated success in automating complex scientific tasks…

Artificial Intelligence · Computer Science 2025-02-14 Quintina Campbell , Sam Cox , Jorge Medina , Brittany Watterson , Andrew D. White

Large language model (LLM) agents extend generative models with reasoning, tool use, and persistent memory, thereby enabling the automation of complex tasks. In healthcare, such systems could support documentation, care coordination, and…

Artificial Intelligence · Computer Science 2026-03-24 Wenxian Yang , Hanzheng Qiu , Bangqun Zhang , Chengquan Li , Zhiyong Huang , Xiaobin Feng , Rongshan Yu , Jiahong Dong

The International Classification of Diseases (ICD) is an authoritative medical classification system of different diseases and conditions for clinical and management purposes. ICD indexing assigns a subset of ICD codes to a medical record.…

Computation and Language · Computer Science 2024-05-30 Xindi Wang , Robert E. Mercer , Frank Rudzicz

ICD coding is a process of assigning the International Classification of Disease diagnosis codes to clinical/medical notes documented by health professionals (e.g. clinicians). This process requires significant human resources, and thus is…

Computation and Language · Computer Science 2020-07-14 Thanh Vu , Dat Quoc Nguyen , Anthony Nguyen

Medical imaging benchmarks often evaluate VLMs on pre-selected 2D images, slices, crops, or patches, making evaluation closer to visual recognition. Real clinical workflows impose a different burden: readers must search through complete…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Weixiang Shen , Chengzhi Shen , Yanzhu Hu , Che Liu , Junde Wu , Jiayuan Zhu , Xiao Han , Zongyue Li , Jingpei Wu , Min Xu , Daguang Xu , Yueming Jin , Benedikt Wiestler , Daniel Rueckert , Jiazhen Pan

Medical Vision-Language Models (VLMs) hold immense promise for complex clinical tasks, but their reasoning capabilities are often constrained by text-only paradigms that fail to ground inferences in visual evidence. This limitation not only…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Zheng Jiang , Heng Guo , Chengyu Fang , Changchen Xiao , Xinyang Hu , Lifeng Sun , Minfeng Xu

Bridging clinical diagnostic reasoning with AI remains a central challenge in medical imaging. We introduce MedCLM, an automated pipeline that converts detection datasets into large-scale medical visual question answering (VQA) data with…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Soo Yong Kim , Suin Cho , Vincent-Daniel Yun , Gyeongyeon Hwang

In modern medicine, clinical diagnosis relies on the comprehensive analysis of primarily textual and visual data, drawing on medical expertise to ensure systematic and rigorous reasoning. Recent advances in large Vision-Language Models…

Artificial Intelligence · Computer Science 2025-07-03 Ziyue Wang , Junde Wu , Linghan Cai , Chang Han Low , Xihong Yang , Qiaxuan Li , Yueming Jin
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