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Medical image analysis is essential to clinical diagnosis and treatment, which is increasingly supported by multi-modal large language models (MLLMs). However, previous research has primarily focused on 2D medical images, leaving 3D images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Fan Bai , Yuxin Du , Tiejun Huang , Max Q. -H. Meng , Bo Zhao

Vision-threatening eye diseases pose a major global health burden, with timely diagnosis limited by workforce shortages and restricted access to specialized care. While multimodal large language models (MLLMs) show promise for medical image…

In clinical practice, crossmodal information including medical images and tabular data is essential for disease diagnosis. There exists a significant modality gap between these data types, which obstructs advancements in crossmodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Tianling Liu , Hongying Liu , Fanhua Shang , Lequan Yu , Tong Han , Liang Wan

Recent advancements in general-purpose or domain-specific multimodal large language models (LLMs) have witnessed remarkable progress for medical decision-making. However, they are designated for specific classification or generative tasks,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Songtao Jiang , Tuo Zheng , Yan Zhang , Yeying Jin , Li Yuan , Zuozhu Liu

The significant breakthroughs of Medical Multi-Modal Large Language Models (Med-MLLMs) renovate modern healthcare with robust information synthesis and medical decision support. However, these models are often evaluated on benchmarks that…

Computation and Language · Computer Science 2024-12-02 Jie Liu , Wenxuan Wang , Yihang Su , Jingyuan Huan , Wenting Chen , Yudi Zhang , Cheng-Yi Li , Kao-Jung Chang , Xiaohan Xin , Linlin Shen , Michael R. Lyu

Medical image segmentation has achieved remarkable success through the continuous advancement of UNet-based and Transformer-based foundation backbones. However, clinical diagnosis in the real world often requires integrating domain…

Computer Vision and Pattern Recognition · Computer Science 2025-04-11 Siyuan Dai , Kai Ye , Guodong Liu , Haoteng Tang , Liang Zhan

Generalist multimodal large language models (MLLMs) have achieved impressive performance across a wide range of vision-language tasks. However, their performance on medical tasks, particularly in zero-shot settings where generalization is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Guimeng Liu , Tianze Yu , Somayeh Ebrahimkhani , Lin Zhi Zheng Shawn , Kok Pin Ng , Ngai-Man Cheung

Medicine is inherently multimodal and multitask, with diverse data modalities spanning text, imaging. However, most models in medical field are unimodal single tasks and lack good generalizability and explainability. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Lijian Xu , Hao Sun , Ziyu Ni , Hongsheng Li , Shaoting Zhang

Recent vision-language models have achieved tremendous advances. However, their computational costs are also escalating dramatically, making model acceleration exceedingly critical. To pursue more efficient vision-language Transformers,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Dachuan Shi , Chaofan Tao , Anyi Rao , Zhendong Yang , Chun Yuan , Jiaqi Wang

Brain imaging analysis is crucial for diagnosing and treating brain disorders, and multimodal large language models (MLLMs) are increasingly supporting it. However, current brain imaging visual question-answering (VQA) benchmarks either…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Zhihao Peng , Cheng Wang , Shengyuan Liu , Zhiying Liang , Zanting Ye , Minjie Ju , PeterYM Woo , Yixuan Yuan

Multimodal large language models have advanced rapidly, but their adoption in medicine is constrained by limited domain coverage, imperfect modality alignment, and insufficient grounded reasoning. We introduce MedMO, a medical multimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ankan Deria , Komal Kumar , Adinath Madhavrao Dukre , Eran Segal , Salman Khan , Imran Razzak

The practical deployment of medical vision-language models (Med-VLMs) necessitates seamless integration of textual data with diverse visual modalities, including 2D/3D images and videos, yet existing models typically employ separate…

Computation and Language · Computer Science 2025-04-22 Songtao Jiang , Yuan Wang , Sibo Song , Yan Zhang , Zijie Meng , Bohan Lei , Jian Wu , Jimeng Sun , Zuozhu Liu

Large Multimodal Models (LMMs) have shown remarkable progress in medical Visual Question Answering (Med-VQA), achieving high accuracy on existing benchmarks. However, their reliability under robust evaluation is questionable. This study…

Artificial Intelligence · Computer Science 2025-06-12 Qianqi Yan , Xuehai He , Xiang Yue , Xin Eric Wang

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon

Medical Vision-Language Models (Med-VLMs) have achieved expert-level proficiency in interpreting diagnostic imaging. However, current models are predominantly trained on professional literature, limiting their ability to communicate…

Computation and Language · Computer Science 2026-04-08 Han Jang , Junhyeok Lee , Heeseong Eum , Kyu Sung Choi

Despite significant advancements in general AI, its effectiveness in the medical domain is limited by the lack of specialized medical knowledge. To address this, we formulate GMAI-VL-5.5M, a multimodal medical dataset created by converting…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Tianbin Li , Yanzhou Su , Wei Li , Bin Fu , Zhe Chen , Ziyan Huang , Guoan Wang , Chenglong Ma , Ying Chen , Ming Hu , Yanjun Li , Pengcheng Chen , Xiaowei Hu , Zhongying Deng , Yuanfeng Ji , Jin Ye , Yu Qiao , Junjun He

While multimodal large language models (MLLMs) exhibit strong performance on single-video tasks (e.g., video question answering), their capability for spatiotemporal pattern reasoning across multiple videos remains a critical gap in pattern…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Nannan Zhu , Yonghao Dong , Teng Wang , Xueqian Li , Shengjun Deng , Yijia Wang , Zheng Hong , Tiantian Geng , Guo Niu , Hanyan Huang , Xiongfei Yao , Shuaiwei Jiao

Medical visual question answering (VQA) is a challenging multimodal task, where Vision-Language Pre-training (VLP) models can effectively improve the generalization performance. However, most methods in the medical field treat VQA as an…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Jiawei Chen , Dingkang Yang , Yue Jiang , Yuxuan Lei , Lihua Zhang

Visual question answering (VQA) in medical imaging aims to support clinical diagnosis by automatically interpreting complex imaging data in response to natural language queries. Existing studies typically rely on distinct visual and textual…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Yuanhe Tian , Chen Su , Junwen Duan , Yan Song

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…