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State-of-the-art medical multi-modal LLMs (med-MLLMs), such as LLaVA-Med and BioMedGPT, primarily depend on scaling model size and data volume, with training driven largely by autoregressive objectives. However, we reveal that this approach…

Recent developments in multimodal methodologies have marked the beginning of an exciting era for models adept at processing diverse data types, encompassing text, audio, and visual content. Models like GPT-4V, which merge computer vision…

Computation and Language · Computer Science 2024-11-15 Xiang Zhang , Senyu Li , Ning Shi , Bradley Hauer , Zijun Wu , Grzegorz Kondrak , Muhammad Abdul-Mageed , Laks V. S. Lakshmanan

Multimodal Large Language Models (MLLMs) have shown success in various general image processing tasks, yet their application in medical imaging is nascent, lacking tailored models. This study investigates the potential of MLLMs in improving…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Ling Yang , Zhanyu Wang , Zhenghao Chen , Xinyu Liang , Luping Zhou

In recent advancements, multimodal large language models (MLLMs) have been fine-tuned on specific medical image datasets to address medical visual question answering (Med-VQA) tasks. However, this common approach of task-specific…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Lai Wei , Wenkai Wang , Xiaoyu Shen , Yu Xie , Zhihao Fan , Xiaojin Zhang , Zhongyu Wei , Wei Chen

While multimodal data integrating diverse imaging and clinical tabular records is crucial for accurate medical diagnosis, the arbitrary absence of specific modalities is prevalent in clinical practice, severely degrading the performance of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Tianling Liu , Lequan Yu , Tong Han , Liang Wan

Medical visual question answering (VQA) is a challenging task that requires answering clinical questions of a given medical image, by taking consider of both visual and language information. However, due to the small scale of training data…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Pengfei Li , Gang Liu , Jinlong He , Zixu Zhao , Shenjun Zhong

Despite significant progress in Multi-modal Large Language Models (MLLMs), their clinical reasoning capacity for multi-modal diagnosis remains largely unexamined. Current benchmarks, mostly single-modality data, can't evaluate progressive…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Gui Wang , Zehao Zhong , YongSong Zhou , Yudong Li , Ende Wu , Wooi Ping Cheah , Rong Qu , Jianfeng Ren , Linlin Shen

Objective: To improve performance of medical entity normalization across many languages, especially when fewer language resources are available compared to English. Materials and Methods: We introduce xMEN, a modular system for…

Computation and Language · Computer Science 2024-12-30 Florian Borchert , Ignacio Llorca , Roland Roller , Bert Arnrich , Matthieu-P. Schapranow

Vision-Language Foundation Models (VLMs), trained on large-scale multimodal datasets, have driven significant advances in Artificial Intelligence (AI) by enabling rich cross-modal reasoning. Despite their success in general domains,…

Medical diagnostic applications require models that can process multimodal medical inputs (images, patient histories, lab results) and generate diverse outputs including both textual reports and visual content (annotations, segmentation…

Medical decision-making requires integrating diverse medical information, from imaging to clinical narratives. These medical modalities are often acquired in a many-to-many manner. However, current medical vision-language pretraining models…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Yuan Gao , Sangwook Kim , Jianzhong You , Chris McIntosh

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

Spatial intelligence requires multimodal large language models (MLLMs) to move beyond single-view perception and reason consistently about objects, visibility, geometry, and interactions across multiple viewpoints. However, progress in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Wei Wang , Yuqian Yuan , Tianwei Lin , Wenqiao Zhang , Siliang Tang , Jun Xiao , Yueting Zhuang

Multi-modal learning has significantly advanced generative AI, especially in vision-language modeling. Innovations like GPT-4V and open-source projects such as LLaVA have enabled robust conversational agents capable of zero-shot task…

Computation and Language · Computer Science 2024-06-17 Zekai Chen , Arda Pekis , Kevin Brown

Cross-lingual cross-modal retrieval has garnered increasing attention recently, which aims to achieve the alignment between vision and target language (V-T) without using any annotated V-T data pairs. Current methods employ machine…

Computer Vision and Pattern Recognition · Computer Science 2024-02-02 Yabing Wang , Fan Wang , Jianfeng Dong , Hao Luo

Visual-language models have advanced the development of universal models, yet their application in medical imaging remains constrained by specific functional requirements and the limited data. Current general-purpose models are typically…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Kaini Wang , Ling Yang , Siping Zhou , Guangquan Zhou , Wentao Zhang , Bin Cui , Shuo Li

This paper extends Cross Modal Generalization (CMG) to open-set environments by proposing the more challenging Open-set Cross Modal Generalization (OSCMG) task. This task evaluates multimodal unified representations in open-set conditions,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Hai Huang , Yan Xia , Shulei Wang , Hanting Wang , Minghui Fang , Shengpeng Ji , Sashuai Zhou , Tao Jin , Zhou Zhao

Multimodal Large Language Models (MLLMs) have tremendous potential to improve the accuracy, availability, and cost-effectiveness of healthcare by providing automated solutions or serving as aids to medical professionals. Despite promising…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Mohammad Shahab Sepehri , Zalan Fabian , Maryam Soltanolkotabi , Mahdi Soltanolkotabi

Medical Visual Question Answering (Med-VQA) represents a critical and challenging subtask within the general VQA domain. Despite significant advancements in general VQA, multimodal large language models (MLLMs) still exhibit substantial…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Hongyu Ge , Longkun Hao , Zihui Xu , Zhenxin Lin , Bin Li , Shoujun Zhou , Hongjin Zhao , Yihang Liu

Multimodal learning leverages complementary information derived from different modalities, thereby enhancing performance in medical image segmentation. However, prevailing multimodal learning methods heavily rely on extensive well-annotated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Xiaogen Zhou , Yiyou Sun , Min Deng , Winnie Chiu Wing Chu , Qi Dou