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Machine Learning with Deep Neural Networks (DNNs) has become a successful tool in solving tasks across various fields of application. However, the complexity of DNNs makes it difficult to understand how they solve their learned task. To…

Machine Learning · Computer Science 2023-06-16 Valerie Krug , Raihan Kabir Ratul , Christopher Olson , Sebastian Stober

Synchronous strategies with data parallelism, such as the Synchronous StochasticGradient Descent (S-SGD) and the model averaging methods, are widely utilizedin distributed training of Deep Neural Networks (DNNs), largely owing to itseasy…

Machine Learning · Computer Science 2022-11-04 Qing Ye , Yuhao Zhou , Mingjia Shi , Yanan Sun , Jiancheng Lv

Background and Objective: Transcranial temporal interference stimulation (tTIS) is a promising non-invasive brain stimulation technique in which interference between electrical current fields extends the possibilities of electrical brain…

Numerical Analysis · Mathematics 2026-02-05 Santtu Söderholm , Maryam Samavaki , Sampsa Pursiainen

GPUs have limited memory and it is difficult to train wide and/or deep models that cause the training process to go out of memory. It is shown in this paper how an open source tool called Large Model Support (LMS) can utilize a high…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-30 Samuel Matzek , Max Grossman , Minsik Cho , Anar Yusifov , Bryant Nelson , Amit Juneja

Histopathological tissue classification is a fundamental task in pathomics cancer research. Precisely differentiating different tissue types is a benefit for the downstream researches, like cancer diagnosis, prognosis and etc. Existing…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Jiatai Lin , Guoqiang Han , Xipeng Pan , Hao Chen , Danyi Li , Xiping Jia , Zhenwei Shi , Zhizhen Wang , Yanfen Cui , Haiming Li , Changhong Liang , Li Liang , Zaiyi Liu , Chu Han

Brain stimulation is a core method in neuroscience. Numerous non-invasive brain stimulation (NIBS) techniques are currently in use in basic and clinical research, and recent advances promise the ability to non-invasively access deep brain…

Neurons and Cognition · Quantitative Biology 2021-11-02 Sebastian J Lehmann , Brian D Corneil

The identification and localisation of pathological tissues in medical images continues to command much attention among deep learning practitioners. When trained on abundant datasets, deep neural networks can match or exceed human…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Jon Middleton , Marko Bauer , Kaining Sheng , Jacob Johansen , Mathias Perslev , Silvia Ingala , Mads Nielsen , Akshay Pai

While several experiments claim that two-level system (TLS) defects in amorphous surfaces/interfaces are responsible for energy relaxation in superconducting resonators and qubits, none can provide quantitative explanation of their data in…

Quantum Physics · Physics 2023-02-03 N. Gorgichuk , T. Junginger , R. de Sousa

We consider the estimation of the average treatment effect in the treated as a function of baseline covariates, where there is a valid (conditional) instrument. We describe two doubly robust (DR) estimators: a locally efficient g-estimator,…

Methodology · Statistics 2019-06-11 Karla DiazOrdaz , Rhian Daniel , Noemi Kreif

The application of Deep Learning (DL) for medical diagnosis is often hampered by two problems. First, the amount of training data may be scarce, as it is limited by the number of patients who have acquired the condition to be diagnosed.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-17 Diyuan Lu , Nenad Polomac , Iskra Gacheva , Elke Hattingen , Jochen Triesch

Accurate brain tumor segmentation is significant for clinical diagnosis and treatment but remains challenging due to tumor heterogeneity. Mamba-based State Space Models have demonstrated promising performance. However, despite their…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Danish Ali , Ajmal Mian , Naveed Akhtar , Ghulam Mubashar Hassan

Double machine learning is a statistical method for leveraging complex black-box models to construct approximately unbiased treatment effect estimates given observational data with high-dimensional covariates, under the assumption of a…

Machine Learning · Statistics 2022-06-03 Nitai Fingerhut , Matteo Sesia , Yaniv Romano

Segmentation of sub-cortical structures from MRI scans is of interest in many neurological diagnosis. Since this is a laborious task machine learning and specifically deep learning (DL) methods have become explored. The structural…

Image and Video Processing · Electrical Eng. & Systems 2021-11-11 Jayanthi Sivaswamy , Alphin J Thottupattu , Mythri V , Raghav Mehta , R Sheelakumari , Chandrasekharan Kesavadas

Background: Drug-drug interactions (DDIs) refer to processes triggered by the administration of two or more drugs leading to side effects beyond those observed when drugs are administered by themselves. Due to the massive number of possible…

Quantitative Methods · Quantitative Biology 2020-12-25 Kyriakos Schwarz , Ahmed Allam , Nicolas Andres Perez Gonzalez , Michael Krauthammer

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

Multi-regional interaction among neuronal populations underlies the brain's processing of rich sensory information in our daily lives. Recent neuroscience and neuroimaging studies have increasingly used naturalistic stimuli and experimental…

Neurons and Cognition · Quantitative Biology 2021-06-08 Yu Takagi , Laurence T. Hunt , Ryu Ohata , Hiroshi Imamizu , Jun-ichiro Hirayama

Objective: A major challenge in designing closed-loop brain-computer interfaces is finding optimal stimulation patterns as a function of ongoing neural activity for different subjects and objectives. Approach: To achieve goal-directed…

Neurons and Cognition · Quantitative Biology 2023-03-22 Matthew J. Bryan , Linxing Preston Jiang , Rajesh P N Rao

Whether transcranial direct current stimulation (tDCS) benefits stroke rehabilitation remains unclear. To investigate how tDCS reorganizes brain circuitry, nineteen post-stroke patients underwent rehabilitation sessions with bi-hemispheric…

Transcranial magnetic stimulation (TMS) is a popular method for the noninvasive stimulation of neurons in the brain. It has become a standard instrument in experimental brain research and is approved for a range of diagnostic and…

Medical Physics · Physics 2023-12-27 Max Koehler , Stefan Goetz

Neural population activity exhibits complex, nonlinear dynamics, varying in time, over trials, and across experimental conditions. Here, we develop Conditionally Linear Dynamical System (CLDS) models as a general-purpose method to…

Neurons and Cognition · Quantitative Biology 2025-10-31 Victor Geadah , Amin Nejatbakhsh , David Lipshutz , Jonathan W. Pillow , Alex H. Williams