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Adaptive deep brain stimulation (aDBS) leverages symptom-related biomarkers to deliver personalized neuromodulation therapy, with the potential to improve treatment efficacy and reduce power consumption compared to conventional DBS.…

Signal Processing · Electrical Eng. & Systems 2026-01-01 Tzu-Chi Liu , Po-Lin Chen , Yi-Chieh Chen , Po-Hsun Tu , Chih-Hua Yeh , Mun-Chun Yeap , Chiung-Chu Chen , Hau-Tieng Wu

Parkinson's disease (PD) affects over ten million people worldwide. Although temporal interference (TI) and deep brain stimulation (DBS) are promising therapies, inter-individual variability limits empirical treatment selection, increasing…

Neurons and Cognition · Quantitative Biology 2026-04-01 Siyuan Du , Siyi Li , Shuwei Bai , Ang Li , Haolin Li , Mingqing Xiao , Yang Pan , Dongsheng Li , Weidi Xie , Yanfeng Wang , Ya Zhang , Chencheng Zhang , Jiangchao Yao

Purpose: This study demonstrated an MR signal multitask learning method for 3D simultaneous segmentation and relaxometry of human brain tissues. Materials and Methods: A 3D inversion-prepared balanced steady-state free precession sequence…

Medical Physics · Physics 2019-12-02 Peng Cao , Jing Liu , Shuyu Tang , Andrew Leynes , Janine M. Lupo , Duan Xu , Peder E. Z. Larson

Drug-Drug Interactions (DDIs) Extraction refers to the efforts to generate hand-made or automatic tools to extract embedded information from text and literature in the biomedical domain. Because of restrictions in hand-made efforts and…

Information Retrieval · Computer Science 2019-08-01 Vahab Mostafapour , Oğuz Dikenelli

Temporal Interference Stimulation (TIS) is a non-invasive neuromodulation technique in which two high-frequency sinusoidal currents with slightly different frequencies generate a low-frequency envelope that can activate deep neural…

Dynamical Systems · Mathematics 2026-05-19 Esteban Paduro , Antoine Chaillet , Mario Sigalotti

Due to the poor illumination and the difficulty in annotating, nighttime conditions pose a significant challenge for autonomous vehicle perception systems. Unsupervised domain adaptation (UDA) has been widely applied to semantic…

Computer Vision and Pattern Recognition · Computer Science 2024-01-03 Fanding Huang , Zihao Yao , Wenhui Zhou

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder. Finding the biomarkers associated with ASD is extremely helpful to understand the underlying roots of the disorder and can lead to earlier diagnosis and more targeted…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Xiaoxiao Li , Nicha C. Dvornek , Juntang Zhuang , Pamela Ventola , James S. Duncan

At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…

Neurons and Cognition · Quantitative Biology 2020-11-12 Lia Papadopoulos , Christopher W. Lynn , Demian Battaglia , Danielle S. Bassett

Background: Brain tumor segmentation has a significant impact on the diagnosis and treatment of brain tumors. Accurate brain tumor segmentation remains challenging due to their irregular shapes, vague boundaries, and high variability.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Zhanyuan Jia , Ni Yao , Danyang Sun , Chuang Han , Yanting Li , Jiaofen Nan , Fubao Zhu , Chen Zhao , Weihua Zhou

Modulating the stiffness of soft actuators is crucial for improving the efficiency of interaction with the environment. However, current stiffness modulation mechanisms are hard to achieve high lateral stiffness and a wide range of bending…

Robotics · Computer Science 2023-12-19 Jianfeng Lin , Ruikang Xiao , Zhao Guo

Objective: To test automated in vivo estimation of active and passive skeletal muscle states using ultrasonic imaging. Background: Current technology (electromyography, dynamometry, shear wave imaging) provides no general, non-invasive…

Image and Video Processing · Electrical Eng. & Systems 2019-07-04 Ryan J. Cunningham , Ian D. Loram

The target theory is the most classical hypothesis explaining radiation-induced cell death, the physical or biological nature of the "target" remains ambiguous. This study hypothesizes that the distribution of DNA double-strand breaks…

Medical Physics · Physics 2025-06-11 Ankang Hu , Wanyi Zhou , Xiyu Luo , Rui Qiu , Junli Li

The activation functions are fundamental to neural networks as they introduce non-linearity into data relationships, thereby enabling deep networks to approximate complex data relations. Existing efforts to enhance neural network…

Machine Learning · Computer Science 2024-09-26 Jiayu Li , Zilong Zhao , Kevin Yee , Uzair Javaid , Biplab Sikdar

This research aimed to develop an intelligent system to evaluate performance and extract behavioral models for children with ASD and neurotypical (TD) children by interacting with a virtual social robot in a music education program using…

Human-Computer Interaction · Computer Science 2026-04-20 Armin Tandiseh , Morteza Memari , Alireza Taheri

Noninvasive brain stimulation (NIBS) by quasistatic electromagnetic means is presently comprised of two methods: Magnetic induction methods (Transcranial magnetic perturbation or TMP) and electrical contact methods (Transcranial electric…

Medical Physics · Physics 2020-06-11 D. J. Sheltraw , B. Inglis , L. Labruna , R. Ivry

Brain tissue segmentation from multimodal MRI is a key building block of many neuroimaging analysis pipelines. Established tissue segmentation approaches have, however, not been developed to cope with large anatomical changes resulting from…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Reuben Dorent , Thomas Booth , Wenqi Li , Carole H. Sudre , Sina Kafiabadi , Jorge Cardoso , Sebastien Ourselin , Tom Vercauteren

CSP is gaining clinical significance owing to its ability to restore a physiological activation sequence in the ventricles. While His bundle pacing (HBP) producing the most physiological activation is preferable, due to implant…

Neuroimaging is essential in brain studies for the diagnosis and identification of disease, structure, and function of the brain in its healthy and disease states. Literature shows that there are advantages of multitasking with some deep…

Image and Video Processing · Electrical Eng. & Systems 2021-06-01 Mohammad Eslami , Solale Tabarestani , Malek Adjouadi

The brain stimulation and its widespread use is one of the most important subjects in studies of neurophysiology. In brain electrical stimulation methods, following the surgery and electrode implantation, electrodes send electrical impulses…

Neurons and Cognition · Quantitative Biology 2019-01-11 Amirmasoud Ahmadi , Sepideh Farakhor Seghinsara , Mohammad Reza Daliri , Vahid Shalchyan

The tight coupling between neuronal activity and the local increase of blood flow termed neurovascular coupling is essential for normal brain function. This mechanism of regulation is compromised in Alzheimer's Disease (AD). In order to…

Neurons and Cognition · Quantitative Biology 2019-05-13 Hélène Geoffroy , Jean Rossier , Armelle Rancillac