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Protein-ligand binding is the process by which a small molecule (drug or inhibitor) attaches to a target protein. Binding affinity, which characterizes the strength of biomolecular interactions, is essential for tackling diverse challenges…

Artificial neural networks (ANNs) are at the core of most Deep learning (DL) algorithms that successfully tackle complex problems like image recognition, autonomous driving, and natural language processing. However, unlike biological brains…

Neural and Evolutionary Computing · Computer Science 2024-09-16 Spyridon Chavlis , Panayiota Poirazi

Network reliability assessment is pivotal for ensuring the robustness of modern infrastructure systems, from power grids to communication networks. While exact reliability computation for binary-state networks is NP-hard, existing…

Machine Learning · Computer Science 2025-03-21 Wei-Chang Yeh

The rapid advancement of models based on artificial intelligence demands innovative monitoring techniques which can operate in real time with low computational costs. In machine learning, especially if we consider artificial neural networks…

Methodology · Statistics 2023-11-10 Anna Malinovskaya , Pavlo Mozharovskyi , Philipp Otto

The prediction of near surface wind speed is becoming increasingly vital for the operation of electrical energy grids as the capacity of installed wind power grows. The majority of predictive wind speed modeling has focused on point-based…

Machine Learning · Computer Science 2017-12-15 Jianan Cao , David J. Farnham , Upmanu Lall

Prediction of material properties from first principles is often a computationally expensive task. Recently, artificial neural networks and other machine learning approaches have been successfully employed to obtain accurate models at a low…

Computational Physics · Physics 2020-07-15 Ruggero Lot , Franco Pellegrini , Yusuf Shaidu , Emine Kucukbenli

In Machine Learning, Artificial Neural Networks (ANNs) are a very powerful tool, broadly used in many applications. Often, the selected (deep) architectures include many layers, and therefore a large amount of parameters, which makes…

Machine Learning · Computer Science 2022-06-29 Matteo Cacciola , Antonio Frangioni , Xinlin Li , Andrea Lodi

Artificial neural networks (ANNs) have become the de facto standard for modeling the human visual system, primarily due to their success in predicting neural responses. However, with many models now achieving similar predictive accuracy, we…

Neurons and Cognition · Quantitative Biology 2025-09-30 Nikolas McNeal , N. Apurva Ratan Murty

Artificial neural network (ANN) is a very useful tool in solving learning problems. Boosting the performances of ANN can be mainly concluded from two aspects: optimizing the architecture of ANN and normalizing the raw data for ANN. In this…

Machine Learning · Computer Science 2017-12-27 Qingjiu Zhang , Shiliang Sun

Rutherford Backscattering Spectrometry (RBS) is an important technique providing elemental information of the near surface region of samples with high accuracy and robustness. However, this technique lacks throughput by the limited rate of…

DNA-binding proteins are a class of proteins which have a specific or general affinity to DNA and include three important components: transcription factors; nucleases, and histones. DNA-binding proteins also perform important roles in many…

Computer Vision and Pattern Recognition · Computer Science 2012-07-12 Sokyna Qatawneh , Afaf Alneaimi , Thamer Rawashdeh , Mmohammad Muhairat , Rami Qahwaji , Stan Ipson

Recurrent Neural Networks (RNNs) are powerful models for sequential data that have the potential to learn long-term dependencies. However, they are computationally expensive to train and difficult to parallelize. Recent work has shown that…

Machine Learning · Statistics 2015-10-07 César Laurent , Gabriel Pereyra , Philémon Brakel , Ying Zhang , Yoshua Bengio

Mixed-signal artificial neural networks (ANNs) that employ analog matrix-multiplication accelerators can achieve higher speed and improved power efficiency. Though analog computing is known to be susceptible to noise and device…

Signal Processing · Electrical Eng. & Systems 2021-07-01 Joseph Ulseth , Zheyuan Zhu , Guifang Li , Shuo Pang

The accuracies for many pattern recognition tasks have increased rapidly year by year, achieving or even outperforming human performance. From the perspective of accuracy, pattern recognition seems to be a nearly-solved problem. However,…

Computer Vision and Pattern Recognition · Computer Science 2020-06-15 Xu-Yao Zhang , Cheng-Lin Liu , Ching Y. Suen

Neural networks are regularly employed in adaptive control of nonlinear systems and related methods of reinforcement learning. A common architecture uses a neural network with a single hidden layer (i.e. a shallow network), in which the…

Optimization and Control · Mathematics 2024-04-18 Andrew Lamperski , Tyler Lekang

Convolutional Neural Network(CNN) has been widely used for image recognition with great success. However, there are a number of limitations of the current CNN based image recognition paradigm. First, the receptive field of CNN is generally…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Dong-Qing Zhang

Continual learning entails learning a sequence of tasks and balancing their knowledge appropriately. With limited access to old training samples, much of the current work in deep neural networks has focused on overcoming catastrophic…

Machine Learning · Computer Science 2023-10-16 Yilin Lyu , Liyuan Wang , Xingxing Zhang , Zicheng Sun , Hang Su , Jun Zhu , Liping Jing

Convolutional neural networks (CNNs) work well on large datasets. But labelled data is hard to collect, and in some applications larger amounts of data are not available. The problem then is how to use CNNs with small data -- as CNNs…

Machine Learning · Statistics 2016-01-19 Yarin Gal , Zoubin Ghahramani

Large outliers break down linear and nonlinear regression models. Robust regression methods allow one to filter out the outliers when building a model. By replacing the traditional least squares criterion with the least trimmed squares…

Optimization and Control · Mathematics 2012-06-07 Gleb Beliakov , Andrei Kelarev , John Yearwood

Artificial neural networks (ANNs) are highly flexible predictive models. However, reliably quantifying uncertainty for their predictions is a continuing challenge. There has been much recent work on "recalibration" of predictive…

Methodology · Statistics 2024-03-12 R. Torres , D. J. Nott , S. A. Sisson , T. Rodrigues , J. G. Reis , G. S. Rodrigues