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Brain-computer interfaces (BCIs), is ways for electronic devices to communicate directly with the brain. For most medical-type brain-computer interface tasks, the activity of multiple units of neurons or local field potentials is sufficient…

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Whole slide image (WSI) classification has emerged as a powerful tool in computational pathology, but remains constrained by domain shifts, e.g., due to different organs, diseases, or institution-specific variations. To address this…

Histopathological whole slide images (WSIs) classification has become a foundation task in medical microscopic imaging processing. Prevailing approaches involve learning WSIs as instance-bag representations, emphasizing significant…

Lung cancer remains one of the leading causes of cancer-related mortality worldwide. Conventional computed tomography (CT) imaging, while essential for detection and staging, has limitations in distinguishing benign from malignant lesions…

Prostate cancer grading from whole-slide images (WSIs) remains a challenging task due to the large-scale nature of WSIs, the presence of heterogeneous tissue structures, and difficulty of selecting diagnostically relevant regions. Existing…

Pathology whole-slide images (WSIs) are widely used for cancer survival analysis because of their comprehensive histopathological information at both cellular and tissue levels, enabling quantitative, large-scale, and prognostically rich…

Whole-slide image (WSI) analysis plays a crucial role in cancer diagnosis and treatment. In addressing the demands of this critical task, self-supervised learning (SSL) methods have emerged as a valuable resource, leveraging their…

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

Gastric endoscopic screening is an effective way to decide appropriate gastric cancer (GC) treatment at an early stage, reducing GC-associated mortality rate. Although artificial intelligence (AI) has brought a great promise to assist…

Microsatellite instability (MSI) is associated with several tumor types and its status has become increasingly vital in guiding patient treatment decisions. However, in clinical practice, distinguishing MSI from its counterpart is…

Malignant lymphoma subtype classification directly impacts treatment strategies and patient outcomes, necessitating classification models that achieve both high accuracy and sufficient explainability. This study proposes a novel explainable…

Feature attributions are post-training analysis methods that assess how various input features of a machine learning model contribute to an output prediction. Their interpretation is straightforward when features act independently, but it…

Several deep learning algorithms have been developed to predict survival of cancer patients using whole slide images (WSIs).However, identification of image phenotypes within the WSIs that are relevant to patient survival and disease…

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…

Recent explainable artificial intelligence (XAI) methods for time series primarily estimate point-wise attribution magnitudes, while overlooking the directional impact on predictions, leading to suboptimal identification of significant…

Whole Slide Image (WSI) representation is critical for cancer subtyping, cancer recognition and mutation prediction.Training an end-to-end WSI representation model poses significant challenges, as a standard gigapixel slide can contain tens…

Computational cytology faces two major challenges: i) instance-level labels are unreliable and prohibitively costly to obtain, ii) witness rates are extremely low. We propose SLAM-AGS, a Slide-Label-Aware Multitask pretraining framework…

Integrated Gradients (IG) and PatternAttribution (PA) are two established explainability methods for neural networks. Both methods are theoretically well-founded. However, they were designed to overcome different challenges. In this work,…

X-Ray Phase-Contrast Imaging (PCI) yields absorption, differential phase, and dark-field images. Computed Tomography (CT) of grating-based PCI can in principle provide high-resolution soft-tissue contrast. Recently, grating-based PCI took…