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The studies of large-scale, high-dimensional data in fields such as genomics and neuroscience have injected new insights into science. Yet, despite advances, they are confronting several challenges, often simultaneously: lack of…

Methodology · Statistics 2024-01-01 Julien Bodelet , Guillaume Blanc , Jiajun Shan , Graciela Muniz Terrera , Oliver Y. Chen

Standard deep neural networks (DNNs) are commonly trained in an end-to-end fashion for specific tasks such as object recognition, face identification, or character recognition, among many examples. This specificity often leads to…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Raphaël Achddou , J. Matias di Martino , Guillermo Sapiro

The principal support vector machines method (Li et al., 2011) is a powerful tool for sufficient dimension reduction that replaces original predictors with their low-dimensional linear combinations without loss of information. However, the…

Machine Learning · Statistics 2019-12-02 Jun Jin , Chao Ying , Zhou Yu

Several reduced order models have been developed for nonlinear dynamical systems. To achieve a considerable speed-up, a hyper-reduction step is needed to reduce the computational complexity due to nonlinear terms. Many hyper-reduction…

Numerical Analysis · Computer Science 2020-01-06 Youngsoo Choi , Deshawn Coombs , Robert Anderson

A variable screening procedure via correlation learning was proposed Fan and Lv (2008) to reduce dimensionality in sparse ultra-high dimensional models. Even when the true model is linear, the marginal regression can be highly nonlinear. To…

Methodology · Statistics 2011-01-19 Jianqing Fan , Yang Feng , Rui Song

Cancer is fundamentally a genetic disease characterized by genetic and epigenetic alterations that disrupt normal gene expression, leading to uncontrolled cell growth and metastasis. High-dimensional microarray datasets pose challenges for…

Quantitative Methods · Quantitative Biology 2025-06-03 Sulaiman khan , Muhammad Ahmad , Fida Ullah , Carlos Aguilar Ibañez , José Eduardo Valdez Rodriguez

The growing use of wide angle image capture devices and the need for fast and accurate image analysis in computer visions have enforced the need for dedicated under-representation approaches. Most recent decomposition methods segment an…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Rémi Giraud , Rodrigo Borba Pinheiro , Yannick Berthoumieu

The data torrent unleashed by current and upcoming astronomical surveys demands scalable analysis methods. Many machine learning approaches scale well, but separating the instrument measurement from the physical effects of interest, dealing…

Computation · Statistics 2023-04-19 Johannes Buchner

This paper introduces a novel framework for dynamic classification in high dimensional spaces, addressing the evolving nature of class distributions over time or other index variables. Traditional discriminant analysis techniques are…

Methodology · Statistics 2025-02-18 Wenbo Ouyang , Ruiyang Wu , Ning Hao , Hao Helen Zhang

Spectral dimensionality reduction methods enable linear separations of complex data with high-dimensional features in a reduced space. However, these methods do not always give the desired results due to irregularities or uncertainties of…

Machine Learning · Statistics 2018-05-21 Momo Matsuda , Keiichi Morikuni , Tetsuya Sakurai

Detecting Earth twins remains challenging because their shallow, long-period transits are difficult to distinguish from background noise. Motivated by the challenge, we developed Segmented-Polynomial-fitting Least Squares (SPLS), a new…

Earth and Planetary Astrophysics · Physics 2025-12-03 Shuyue Zheng , Fabo Feng , Yicheng Rui

Microarray studies, in order to identify genes associated with an outcome of interest, usually produce noisy measurements for a large number of gene expression features from a small number of subjects. One common approach to analyzing such…

Methodology · Statistics 2021-04-21 Linh Nghiem , Francis K. C. Hui , Samuel Mueller , A. H. Welsh

The abundance of new cosmological data becoming available means that a wider range of cosmological models are testable than ever before. However, an important distinction must be made between parameter fitting and model selection. While…

Astrophysics · Physics 2009-11-13 Pia Mukherjee , David Parkinson , Andrew R. Liddle

Mass spectrometry provides a high-throughput way to identify proteins in biological samples. In a typical experiment, proteins in a sample are first broken into their constituent peptides. The resulting mixture of peptides is then subjected…

Applications · Statistics 2010-11-10 Qunhua Li , Michael J. MacCoss , Matthew Stephens

Numerical resolution of high-dimensional nonlinear PDEs remains a huge challenge due to the curse of dimensionality. Starting from the weak formulation of the Lawson-Euler scheme, this paper proposes a stochastic particle method (SPM) by…

Numerical Analysis · Mathematics 2025-02-11 Zhengyang Lei , Sihong Shao , Yunfeng Xiong

Bayesian inference methods rely on numerical algorithms for both model selection and parameter inference. In general, these algorithms require a high computational effort to yield reliable estimates. One of the major challenges in…

Quantitative Methods · Quantitative Biology 2018-08-09 Patricio Maturana , Brendon J. Brewer , Steffen Klaere , Remco Bouckaert

Despite the success of existing tensor factorization methods, most of them conduct a multilinear decomposition, and rarely exploit powerful modeling frameworks, like deep neural networks, to capture a variety of complicated interactions in…

Machine Learning · Computer Science 2020-07-16 Shikai Fang , Zheng Wang , Zhimeng Pan , Ji Liu , Shandian Zhe

An important part of breast cancer staging is the assessment of the sentinel axillary node for early signs of tumor spreading. However, this assessment by pathologists is not always easy and retrospective surveys often requalify the status…

Quantitative Methods · Quantitative Biology 2024-04-30 Eric Bonnet

Parameterized partial differential equations (PDEs) underpin the mathematical modeling of complex systems in diverse domains, including engineering, healthcare, and physics. A central challenge in using PDEs for real-world applications is…

Machine Learning · Computer Science 2026-04-07 Xuyang Li , Mahdi Masmoudi , Rami Gharbi , Nizar Lajnef , Vishnu Naresh Boddeti

Many computer vision problems (e.g., camera calibration, image alignment, structure from motion) are solved with nonlinear optimization methods. It is generally accepted that second order descent methods are the most robust, fast, and…

Computer Vision and Pattern Recognition · Computer Science 2014-05-06 Xuehan Xiong , Fernando De la Torre
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