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Accurate prediction of treatment outcomes in lung cancer remains challenging due to the sparsity, heterogeneity, and contextual overload of real-world electronic health data. Traditional models often fail to capture semantic information…

In the hospital world there are several complex combinatory problems, and solving these problems is important to increase the degree of patients' satisfaction and the quality of care offered. The problems in the healthcare are complex since…

Artificial Intelligence · Computer Science 2022-08-08 Marco Mochi

Background. In the realm of software engineering, there are widely accepted guidelines for reporting and creating laboratory packages. Unfortunately, the landscape differs considerably in the emerging field of quantum computing. To the best…

Software Engineering · Computer Science 2024-05-08 Enrique Moguel , José Antonio Parejo , Antonio Ruiz-Cortés , Jose Garcia-Alonso , Juan Manuel Murillo

Current clinical decision-making in oncology relies on averages of large patient populations to both assess tumor status and treatment outcomes. However, cancers exhibit an inherent evolving heterogeneity that requires an individual…

The ability to accurately estimate risk of developing breast cancer would be invaluable for clinical decision-making. One promising new approach is to integrate image-based risk models based on deep neural networks. However, one must take…

Image and Video Processing · Electrical Eng. & Systems 2020-09-17 Yue Liu , Hossein Azizpour , Fredrik Strand , Kevin Smith

During the early stages of developing Case-Based Reasoning (CBR) systems the definition of similarity measures is challenging since this task requires transferring implicit knowledge of domain experts into knowledge representations. While…

Human-Computer Interaction · Computer Science 2021-06-10 Kerstin Bach , Paul Jarle Mork

Heterogeneity in the cell population of cancer tissues poses many challenges in cancer diagnosis and treatment. Studying the heterogeneity in cell populations from gene expression measurement data in the context of cancer research is a…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-31 Anik Chaudhuri , Anwoy Mohanty , Manoranjan Satpathy

Empathy is a powerful yet often overlooked element in software engineering (SE), supporting better teamwork, smoother communication, and effective decision-making.This paper introduces 17 actionable empathy guidelines designed to support…

Software Engineering · Computer Science 2026-01-19 Hashini Gunatilake , John Grundy , Rashina Hoda , Ingo Mueller

Gastrointestinal (GI) tract cancers account for a substantial portion of the global cancer burden, where early diagnosis is critical for improved management and patient outcomes. The complex aetiologies and overlapping symptoms across GI…

Computation and Language · Computer Science 2025-03-19 Aniket Deroy , Subhankar Maity

Decision support is a probabilistic and quantitative method designed for modeling problems in situations with ambiguity. Computer technology can be employed to provide clinical decision support and treatment recommendations. The problem of…

Artificial Intelligence · Computer Science 2018-12-06 Ying Shen , Joël Colloc , Armelle Jacquet-Andrieu , Ziyi Guo , Yong Liu

Our work concerns the elucidation of the cancer (epi)genome, transcriptome and proteome to better understand the complex interplay between a cancer cell's molecular state and its response to anti-cancer therapy. To study the problem, we…

Artificial Intelligence · Computer Science 2010-12-09 Matt Holford , James McCusker , Kei Cheung , Michael Krauthammer

Software is a great enabler for a number of projects that otherwise would be impossible to perform. Such projects include Space Exploration, Weather Modeling, Genome Projects, and many others. It is critical that software aiding these…

Software Engineering · Computer Science 2023-02-10 Aedin Pereira , Julia Ding , Zaina Ali , Rodion Podorozhny

Standardisation of healthcare has been the focus of hospital management and clinicians since the 1990's. Electronic health records were already intended to provide clinicians with real-time access to clinical knowledge and care plans while…

Computers and Society · Computer Science 2020-04-13 Scott McLachlan

Background: Philosophers of science including Collins, Feyerabend, Kuhn and Latour have all emphasized the importance of consensus within scientific communities of practice. Consensus is important for maintaining legitimacy with outsiders,…

Software Engineering · Computer Science 2018-02-20 Pontus Johnson , Paul Ralph , Mathias Ekstedt , Iaakov Exman , Michael Goedicke

We propose a new multi-network-based strategy to integrate different layers of genomic information and use them in a coordinate way to identify driving cancer genes. The multi-networks that we consider combine transcription factor…

Molecular Networks · Quantitative Biology 2015-12-10 Laura Cantini , Enzo Medico , Santo Fortunato , Michele Caselle

The presence of detailed clinical information in electronic health record (EHR) systems presents promising prospects for enhancing patient care through automated retrieval techniques. Nevertheless, it is widely acknowledged that accessing…

Information Retrieval · Computer Science 2024-09-13 Abderrahim Oussama Batouche , Eugen Czeizler , Miika Koskinen , Tuomas Mirtti , Antti Sakari Rannikko

The demand of transparency of clinical research results, the need of accelerating the process of transferring innovation in the daily medical practice as well as assuring patient safety and product efficacy make it necessary to extend the…

Software Engineering · Computer Science 2013-01-10 Daniela Luzi , Fabrizio Pecoraro

While developing an information system for the University of Bern, we were faced with two major issues: managing software changes and adapting Business Information Models. Software techniques well-suited to software development teams exist,…

Software Engineering · Computer Science 2008-04-03 Patrick Chénais

Our analysis of recent AI4H publications reveals that, despite a trend toward utilizing open datasets and sharing modeling code, 74% of AI4H papers still rely on private datasets or do not share their code. This is especially concerning in…

Computers and Society · Computer Science 2026-03-05 John Wu , Zhenbang Wu , Jimeng Sun

To interpret the genetic profile present in a patient sample, it is necessary to know which mutations have important roles in the development of the corresponding cancer type. Named entity recognition is a core step in the text mining…

Computation and Language · Computer Science 2021-06-16 Jiarun Cao , Elke M van Veen , Niels Peek , Andrew G Renehan , Sophia Ananiadou