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A stepped wedge design is a unidirectional crossover design where clusters are randomized to distinct treatment sequences. While model-based analysis of stepped wedge designs is standard practice to evaluate treatment effects accounting for…

Methodology · Statistics 2024-09-13 Bingkai Wang , Xueqi Wang , Fan Li

We propose a change-point detection method for large scale multiple testing problems with data having clustered signals. Unlike the classic change-point setup, the signals can vary in size within a cluster. The clustering structure on the…

Methodology · Statistics 2021-10-07 Hongyuan Cao , Wei Biao Wu

In this article, we develop methods for sample size and power calculations in four-level intervention studies when intervention assignment is carried out at any level, with a particular focus on cluster randomized trials (CRTs). CRTs…

Methodology · Statistics 2022-09-07 Xueqi Wang , Elizabeth L. Turner , John S. Preisser , Fan Li

There are various cluster validity indices used for evaluating clustering results. One of the main objectives of using these indices is to seek the optimal unknown number of clusters. Some indices work well for clusters with different…

Machine Learning · Statistics 2024-01-09 Nathakhun Wiroonsri

We show how clustering standard errors in one or more dimensions can be justified in M-estimation when there is sampling or assignment uncertainty. Since existing procedures for variance estimation are either conservative or invalid, we…

Econometrics · Economics 2024-11-21 Ruonan Xu , Luther Yap

We address estimation of intervention effects in experimental designs in which (a) interventions are assigned at the cluster level; (b) clusters are selected to form pairs, matched on observed characteristics; and (c) intervention is…

Methodology · Statistics 2014-11-24 Zhenke Wu , Constantine E. Frangakis , Thomas A. Louis , Daniel O. Scharfstein

Missing observations are common in cluster randomised trials. Approaches taken to handling such missing data include: complete case analysis, single-level multiple imputation that ignores the clustering, multiple imputation with a fixed…

Methodology · Statistics 2014-07-18 Karla Diaz-Ordaz , Michael G. Kenward , Manuel Gomes , Richard Grieve

Interference occurs when the potential outcomes of a unit depend on the treatment of others. Interference can be highly heterogeneous, where treating certain individuals might have a larger effect on the population's overall outcome. A…

Methodology · Statistics 2025-04-11 Samantha G Dean , Georgia Papadogeorgou , Laura Forastiere

We introduce a method for validation of results obtained by clustering analysis of data. The method is based on resampling the available data. A figure of merit that measures the stability of clustering solutions against resampling is…

Computational Physics · Physics 2007-05-23 Erel Levine , Eytan Domany

An automatic procedure to perform sub-clustering on large samples is presented. At each iteration, the most diverse cluster is sub-clustered, and the global diversity of the new classification is compared to the previous one. The process…

Instrumentation and Methods for Astrophysics · Physics 2025-05-15 Hugo Chambon , Didier Fraix-Burnet

Cluster-level dynamic treatment regimens can be used to guide sequential, intervention or treatment decision-making at the cluster level in order to improve outcomes at the individual or patient-level. In a cluster-level DTR, the…

Methodology · Statistics 2016-07-15 Timothy NeCamp , Amy Kilbourne , Daniel Almirall

VARCLUST algorithm is proposed for clustering variables under the assumption that variables in a given cluster are linear combinations of a small number of hidden latent variables, corrupted by the random noise. The entire clustering task…

Identifying the number $K$ of clusters in a dataset is one of the most difficult problems in clustering analysis. A choice of $K$ that correctly characterizes the features of the data is essential for building meaningful clusters. In this…

Methodology · Statistics 2019-05-06 Adriano Zanin Zambom , Julian A. Collazos , Ronaldo Dias

The performance (accuracy and robustness) of several clustering algorithms is studied for linearly dependent random variables in the presence of noise. It turns out that the error percentage quickly increases when the number of observations…

Applications · Statistics 2009-11-13 Pamela Minicozzi , Fabio Rapallo , Enrico Scalas , Francesco Dondero

The determination of cluster centers generally depends on the scale that we use to analyze the data to be clustered. Inappropriate scale usually leads to unreasonable cluster centers and thus unreasonable results. In this study, we first…

Machine Learning · Statistics 2016-10-20 Xiurui Geng , Hairong Tang

We consider the problem of the statistical uncertainty of the correlation matrix in the optimization of a financial portfolio. We show that the use of clustering algorithms can improve the reliability of the portfolio in terms of the ratio…

Physics and Society · Physics 2008-12-02 Vincenzo Tola , Fabrizio Lillo , Mauro Gallegati , Rosario N. Mantegna

We address general-shaped clustering problems under very weak parametric assumptions with a two-step hybrid robust clustering algorithm based on trimmed k-means and hierarchical agglomeration. The algorithm has low computational complexity…

Methodology · Statistics 2022-01-19 Luca Insolia , Domenico Perrotta

Clustering methods such as k-means have found widespread use in a variety of applications. This paper proposes a formal testing procedure to determine whether a null hypothesis of a single cluster, indicating homogeneity of the data, can be…

Econometrics · Economics 2019-07-18 Andrew J. Patton , Brian M. Weller

We discuss recently developed methods that quantify the stability and generalizability of statistical findings under distributional changes. In many practical problems, the data is not drawn i.i.d. from the target population. For example,…

Methodology · Statistics 2023-10-05 Dominik Rothenhäusler , Peter Bühlmann

A rank-invariant clustering of variables is introduced that is based on the predictive strength between groups of variables, i.e., two groups are assigned a high similarity if the variables in the first group contain high predictive…

Methodology · Statistics 2023-12-29 Sebastian Fuchs , Yuping Wang
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