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When a fraction of a population becomes immune to an infectious disease, the population-wide infection risk decreases nonlinearly due to collective protection, known as herd immunity. Some studies based on mean-field models suggest that…

Physics and Society · Physics 2025-09-03 Takayuki Hiraoka , Zahra Ghadiri , Abbas K. Rizi , Mikko Kivelä , Jari Saramäki

Human behaviour strongly influences the spread of infectious diseases: understanding the interplay between epidemic dynamics and adaptive behaviours is essential to improve response strategies to epidemics, with the goal of containing the…

Physics and Society · Physics 2024-08-21 Marco Mancastroppa , Alessandro Vezzani , Vittoria Colizza , Raffaella Burioni

This article reviews quantitative methods to estimate the basic reproduction number of pandemic influenza, a key threshold quantity to help determine the intensity of interventions required to control the disease. Although it is difficult…

Populations and Evolution · Quantitative Biology 2009-11-13 Gerardo Chowell , Hiroshi Nishiura

Two versions of the susceptible-infected-susceptible epidemic model, which have different transmission rules, are analysed. Both models are considered on a weighted network to simulate a mitigation in the connection between the individuals.…

Statistical Mechanics · Physics 2021-02-10 C. Dias , M. O. Hase

In the last decades, the interest to understand the connection between brain and body has grown notably. For example, in psychoneuroimmunology many studies associate stress, arising from many different sources and situations, to changes in…

Quantitative Methods · Quantitative Biology 2022-07-27 Maria Elena Gonzalez Herrero , Christian Kuehn

Epidemic outbreaks pose significant challenges to public health and socio-economic stability, necessitating a comprehensive understanding of disease transmission dynamics and effective control strategies. This article discusses the…

Physics and Society · Physics 2023-10-20 Sourin Chatterjee , Ahad N. Zehmakan , Sujay Rastogi

During an epidemic, such as the COVID-19 pandemic, policy-makers are faced with the decision of implementing effective, yet socioeconomically costly intervention strategies, such as school and workplace closure, physical distancing, etc. In…

Dynamical Systems · Mathematics 2024-07-18 Vasiliki Bitsouni , Nikolaos Gialelis , Vasilis Tsilidis

The Susceptible-Infected-Recovered (SIR) model is the cornerstone of epidemiological models. However, this specification depends on two parameters only, which implies a lack of flexibility and the difficulty to replicate the volatile…

Populations and Evolution · Quantitative Biology 2020-11-17 Christian Gourieroux , Yang Lu

We investigate methods to vaccinate contact networks -- i.e. removing nodes in such a way that disease spreading is hindered as much as possible -- with respect to their cost-efficiency. Any real implementation of such protocols would come…

Populations and Evolution · Quantitative Biology 2017-11-01 Petter Holme , Nelly Litvak

We examine here the effects of recurrent vaccination and waning immunity on the establishment of an endemic equilibrium in a population. An individual-based model that incorporates memory effects for transmission rate during infection and…

Populations and Evolution · Quantitative Biology 2024-11-22 Félix Foutel-Rodier , Arthur Charpentier , Hélène Guérin

This paper investigates the dynamics of infectious diseases with a non-exponentially distributed infectious period. This is achieved by considering a multi-stage infection model on networks. Using pairwise approximation with a standard…

Physics and Society · Physics 2015-11-23 N. Sherborne , K. B. Blyuss , I. Z. Kiss

Aging includes both continuous gradual decline from microscopic mechanisms together with major deficit onset events such as morbidity, disability and ultimately death. These deficit events are stochastic, obscuring the connection between…

Quantitative Methods · Quantitative Biology 2025-12-25 Glen Pridham , Kenneth Rockwood , Andrew Rutenberg

In contrast to the many theoretical studies on the transmission of human-mosquitoes malaria infection, few studies have considered a multiple structure model formulations including (i) the chronological age of humans and mosquitoes…

Analysis of PDEs · Mathematics 2021-01-01 Quentin Richard , Marc Choisy , Thierry Lefèvre , Ramsès Djidjou-Demasse

The threat of avian influenza and the 2004-2005 influenza vaccine supply shortage in the United States has sparked a debate about optimal vaccination strategies to reduce the burden of morbidity and mortality caused by the influenza virus.…

Populations and Evolution · Quantitative Biology 2010-02-10 Shweta Bansal , Babak Pourbohloul , Lauren Ancel Meyers

Understanding how age-specific social contact patterns and susceptibility influence infectious disease transmission is crucial for accurate epidemic modeling. This study presents an eigenvector-based sensitivity analysis framework to…

Populations and Evolution · Quantitative Biology 2025-11-21 Evans Kiptoo Korir , Zsolt Vizi

The time-dependent reproduction number Rt can be used to track pathogen transmission and to assess the efficacy of interventions. This quantity can be estimated by fitting renewal equation models to time series of infectious disease case…

Populations and Evolution · Quantitative Biology 2025-01-30 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

We propose a numerical method for approximating integro-differential equations arising in age-of-infection epidemic models. The method is based on a non-standard finite differences approximation of the integral term appearing in the…

Numerical Analysis · Mathematics 2024-07-22 Eleonora Messina , Mario Pezzella , Antonia Vecchio

We propose an epidemic model for the spread of vector-borne diseases. The model, which is built extending the classical susceptible-infected-susceptible model, accounts for two populations -- humans and vectors -- and for cross-contagion…

Systems and Control · Electrical Eng. & Systems 2025-10-21 Lorenzo Zino , Alessandro Casu , Alessandro Rizzo

We introduce a two-strain model with asymmetric temporary immunity periods and partial cross-immunity. We derive explicit conditions for competitive exclusion and coexistence of the strains depending on the strain-specific basic…

Dynamical Systems · Mathematics 2023-06-28 Matthew D. Johnston , Bruce Pell , David A. Rubel

The COVID-19 pandemic led to widespread interest in epidemiological models. In this context the role of vaccination in influencing the spreading of the disease is of particular interest. There has also been a lot of debate on the role of…

Dynamical Systems · Mathematics 2023-07-25 Aytül Gökçe , Burcu Gürbüz , Alan D. Rendall