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Despite significant progress, large language models (LLMs) still struggle with long contexts due to memory limitations and their inability to tackle complex and long-context tasks. Additionally, LLMs often suffer from a lack of transparency…

Computation and Language · Computer Science 2025-08-29 Zhirui Chen , Wei Shen , Jiashui Huang , Ling Shao

The rapid expansion of publicly-available medical data presents a challenge for clinicians and researchers alike, increasing the gap between the volume of scientific literature and its applications. The steady growth of studies and findings…

Artificial Intelligence · Computer Science 2025-08-06 Taine J. Elliott , Stephen P. Levitt , Ken Nixon , Martin Bekker

Retrieval augmented generation mitigates limitations of large language models in factual consistency and knowledge updating by introducing external knowledge. However, practical applications still suffer from semantic misalignment between…

Computation and Language · Computer Science 2026-03-06 Xin Chen , Saili Uday Gadgil , Jiarong Qiu

Knowledge graphs and large language models (LLMs) are key tools for biomedical knowledge integration and reasoning, facilitating structured organization of scientific articles and discovery of complex semantic relationships. However,…

Computation and Language · Computer Science 2025-04-01 Yichun Feng , Jiawei Wang , Ruikun He , Lu Zhou , Yixue Li

Large Language Models (LLMs) have achieved impressive performance across a wide range of applications. However, they often suffer from hallucinations in knowledge-intensive domains due to their reliance on static pretraining corpora. To…

Information Retrieval · Computer Science 2026-02-10 Lihui Liu , Jiayuan Ding , Subhabrata Mukherjee , Carl J. Yang

Despite the impressive advancements of Large Language Models (LLMs) in generating text, they are often limited by the knowledge contained in the input and prone to producing inaccurate or hallucinated content. To tackle these issues,…

Information Retrieval · Computer Science 2024-05-29 Yu Wang , Nedim Lipka , Ruiyi Zhang , Alexa Siu , Yuying Zhao , Bo Ni , Xin Wang , Ryan Rossi , Tyler Derr

Large Language Models (LLMs) have shown impressive capabilities in generating human-like responses. However, their lack of domain-specific knowledge limits their applicability in healthcare settings, where contextual and comprehensive…

Computation and Language · Computer Science 2024-03-14 Subash Neupane , Shaswata Mitra , Sudip Mittal , Noorbakhsh Amiri Golilarz , Shahram Rahimi , Amin Amirlatifi

Advancements in natural language processing have revolutionized the way we can interact with digital information systems, such as databases, making them more accessible. However, challenges persist, especially when accuracy is critical, as…

Computation and Language · Computer Science 2025-11-12 Larissa Pusch , Tim O. F. Conrad

Generative AI, particularly Large Language Models, increasingly integrates graph-based representations to enhance reasoning, retrieval, and structured decision-making. Despite rapid advances, there remains limited clarity regarding when,…

Artificial Intelligence · Computer Science 2026-04-21 Hamed Jelodar , Samita Bai , Mohammad Meymani , Parisa Hamedi , Roozbeh Razavi-Far , Ali Ghorbani

Language models (LMs), including large language models (such as ChatGPT), have the potential to assist clinicians in generating various clinical notes. However, LMs are prone to produce ``hallucinations'', i.e., generated content that is…

Computation and Language · Computer Science 2024-07-23 Fenglin Liu , Bang Yang , Chenyu You , Xian Wu , Shen Ge , Zhangdaihong Liu , Xu Sun , Yang Yang , David A. Clifton

Materials discovery and design are essential for advancing technology across various industries by enabling the development of application-specific materials. Recent research has leveraged Large Language Models (LLMs) to accelerate this…

Computation and Language · Computer Science 2025-02-11 Shrinidhi Kumbhar , Venkatesh Mishra , Kevin Coutinho , Divij Handa , Ashif Iquebal , Chitta Baral

Graph-structured retrieval-augmented generation (RAG) systems can improve answer quality on multi-hop questions, but many current systems rely on large language models (LLMs) to extract entities, relations, and summaries during indexing.…

Computation and Language · Computer Science 2026-05-20 Roman Prosvirnin , Sergei Kuznetsov , Seungmin Jin

Biomedical knowledge graphs (KGs) are vital for drug discovery and clinical decision support but remain incomplete. Large language models (LLMs) excel at extracting biomedical relations, yet their outputs lack standardization and alignment…

Information Retrieval · Computer Science 2025-12-01 Olawumi Olasunkanmi , Mathew Satusky , Hong Yi , Chris Bizon , Harlin Lee , Stanley Ahalt

Building explainable systems is a critical problem in the field of Natural Language Processing (NLP), since most machine learning models provide no explanations for the predictions. Existing approaches for explainable machine learning…

Computation and Language · Computer Science 2019-06-12 Hui Liu , Qingyu Yin , William Yang Wang

Effective generation of novel hypotheses is instrumental to scientific progress. So far, researchers have been the main powerhouse behind hypothesis generation by painstaking data analysis and thinking (also known as the Eureka moment). In…

Artificial Intelligence · Computer Science 2024-12-20 Yangqiaoyu Zhou , Haokun Liu , Tejes Srivastava , Hongyuan Mei , Chenhao Tan

The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…

Computation and Language · Computer Science 2024-11-18 Diya Li , Asim Kadav , Aijing Gao , Rui Li , Richard Bourgon

Inductive reasoning is a core problem-solving capacity: humans can identify underlying principles from a few examples, which robustly generalize to novel scenarios. Recent work evaluates large language models (LLMs) on inductive reasoning…

Machine Learning · Computer Science 2024-06-03 Ruocheng Wang , Eric Zelikman , Gabriel Poesia , Yewen Pu , Nick Haber , Noah D. Goodman

In Question Answering (QA), Retrieval Augmented Generation (RAG) has revolutionized performance in various domains. However, how to effectively capture multi-document relationships, particularly critical for biomedical tasks, remains an…

Computation and Language · Computer Science 2025-04-03 Lingxiao Guan , Yuanhao Huang , Jie Liu

Large language models (LLMs) have demonstrated their ability to learn in-context, allowing them to perform various tasks based on a few input-output examples. However, the effectiveness of in-context learning is heavily reliant on the…

Computation and Language · Computer Science 2024-01-29 Liang Wang , Nan Yang , Furu Wei

Large language models record impressive performance on many natural language processing tasks. However, their knowledge capacity is limited to the pretraining corpus. Retrieval augmentation offers an effective solution by retrieving context…

Computation and Language · Computer Science 2023-11-22 Sai Munikoti , Anurag Acharya , Sridevi Wagle , Sameera Horawalavithana