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Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

Clinical patient notes are critical for documenting patient interactions, diagnoses, and treatment plans in medical practice. Ensuring accurate evaluation of these notes is essential for medical education and certification. However, manual…

Computation and Language · Computer Science 2024-01-25 Jingyu Xu , Yifeng Jiang , Bin Yuan , Shulin Li , Tianbo Song

Electronic health record (EHR) systems present clinicians with vast repositories of clinical information, creating a significant cognitive burden where critical details are easily overlooked. While Large Language Models (LLMs) offer…

Computation and Language · Computer Science 2026-03-17 Samuel Thio , Matthew Lewis , Spiros Denaxas , Richard JB Dobson

Research on emergency and mass casualty incident (MCI) triage has been limited by the absence of openly usable, reproducible benchmarks. Yet these scenarios demand rapid identification of the patients most in need, where accurate…

Machine Learning · Computer Science 2026-03-31 Joshua Sebastian , Karma Tobden , KMA Solaiman

Extracting structured information from clinical notes requires navigating a dense web of interdependent variables where the value of one attribute logically constrains others. Existing Large Language Model (LLM)-based extraction pipelines…

Large language models (LLMs) have achieved remarkable performance on diverse benchmarks, yet existing evaluation practices largely rely on coarse summary metrics that obscure underlying reasoning abilities. In this work, we propose novel…

Methodology · Statistics 2026-03-17 Jia Liu , Zhiyu Xu , Yuqi Gu

Longitudinal health agents must reason across multi-source trajectories that combine continuous device streams, sparse clinical exams, and episodic life events - yet evaluating them is hard: real-world data cannot be released at scale, and…

Artificial Intelligence · Computer Science 2026-04-06 Chao Li , Cailiang Liu , Ang Gao , Kexin Deng , Shu Zhang , Langping Xu , Xiaotong Shi , Xionghao Ding , Jian Pei , Xun Jiang

A crucial component for clinical risk prediction is developing a reliable prediction model is collecting high-quality time series clinical events. In this work, we release such a dataset that consists of 22,588,586 Clinical Time Series…

Artificial Intelligence · Computer Science 2025-11-19 Jing Wang , Xing Niu , Tong Zhang , Jie Shen , Juyong Kim , Jeremy C. Weiss

Electronic Medical Records (EMRs), while integral to modern healthcare, present challenges for clinical reasoning and diagnosis due to their complexity and information redundancy. To address this, we proposed medIKAL (Integrating Knowledge…

Computation and Language · Computer Science 2025-02-18 Mingyi Jia , Junwen Duan , Yan Song , Jianxin Wang

Accurate clinical coding is essential for healthcare documentation, billing, and decision-making. While prior work shows that off-the-shelf LLMs struggle with this task, evaluations based on exact match metrics often overlook errors where…

Computation and Language · Computer Science 2025-10-10 Zhangdie Yuan , Han-Chin Shing , Mitch Strong , Chaitanya Shivade

Multimodal large language models (MLLMs) have advanced clinical tasks for common conditions, but their performance on rare diseases remains largely untested. In rare-disease scenarios, clinicians often lack prior clinical knowledge, forcing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Junzhi Ning , Jiashi Lin , Yingying Fang , Wei Li , Jiyao Liu , Cheng Tang , Chenglong Ma , Wenhao Tang , Tianbin Li , Ziyan Huang , Guang Yang , Junjun He

An increasing amount of research is being devoted to applying machine learning methods to electronic health record (EHR) data for various clinical purposes. This growing area of research has exposed the challenges of the accessibility of…

Machine Learning · Computer Science 2022-12-22 Mehak Gupta , Brennan Gallamoza , Nicolas Cutrona , Pranjal Dhakal , Raphael Poulain , Rahmatollah Beheshti

Clinical notes in Electronic Health Records (EHRs) capture rich temporal information on events, clinician reasoning, and lifestyle factors often missing from structured data. Leveraging them for predictive modeling can be impactful for…

Computation and Language · Computer Science 2026-05-08 Rochana Chaturvedi , Yue Zhou , Andrew D. Boyd , Brian T. Layden , Mudassir Rashid , Lu Cheng , Ali Cinar , Barbara Di Eugenio

Large Language Models (LLMs) have transformed natural language processing and extended their powerful capabilities to multi-modal domains. As LLMs continue to advance, it is crucial to develop diverse and appropriate metrics for their…

Machine Learning · Computer Science 2024-10-15 Lai Wei , Zhiquan Tan , Chenghai Li , Jindong Wang , Weiran Huang

In semi-supervised learning, methods that rely on confidence learning to generate pseudo-labels have been widely proposed. However, increasing research finds that when faced with noisy and biased data, the model's representation network is…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Yanbiao Ma , Licheng Jiao , Fang Liu , Lingling Li , Shuyuan Yang , Xu Liu

Structured data offers a sophisticated mechanism for the organization of information. Existing methodologies for the text-serialization of structured data in the context of large language models fail to adequately address the heterogeneity…

Computation and Language · Computer Science 2024-02-20 YiQiu Guo , Yuchen Yang , Ya Zhang , Yu Wang , Yanfeng Wang

The Medical Information Mart for Intensive Care (MIMIC) datasets have become the Kernel of Digital Health Research by providing freely accessible, deidentified records from tens of thousands of critical care admissions, enabling a broad…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Afifa Khaled , Mohammed Sabir , Rizwan Qureshi , Camillo Maria Caruso , Valerio Guarrasi , Suncheng Xiang , S Kevin Zhou

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

Computation and Language · Computer Science 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

Augmentation of disease diagnosis and decision-making in healthcare with machine learning algorithms is gaining much impetus in recent years. In particular, in the current epidemiological situation caused by COVID-19 pandemic, swift and…

Computers and Society · Computer Science 2021-02-23 Leopold Franz , Yash Raj Shrestha , Bibek Paudel

Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to evaluate the capabilities of advanced…

Computation and Language · Computer Science 2025-11-10 Chong Shao , Douglas Snyder , Chiran Li , Bowen Gu , Kerry Ngan , Chun-Ting Yang , Jiageng Wu , Richard Wyss , Kueiyu Joshua Lin , Jie Yang
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